- Genetic factors in colorectal cancer
- Cancer-related molecular mechanisms research
- Metabolism, Diabetes, and Cancer
- Immunodeficiency and Autoimmune Disorders
- Cancer, Hypoxia, and Metabolism
- Rheumatoid Arthritis Research and Therapies
- Cancer Cells and Metastasis
- Cancer, Lipids, and Metabolism
- Metastasis and carcinoma case studies
- MicroRNA in disease regulation
- Prostate Cancer Treatment and Research
- Circular RNAs in diseases
- Cancer, Stress, Anesthesia, and Immune Response
- TGF-β signaling in diseases
- T-cell and B-cell Immunology
- Mechanisms of cancer metastasis
- Ferroptosis and cancer prognosis
Huzhou University
2014-2021
Third People's Hospital of Huzhou
2014
Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII, also known as NR2F2) promotes metastasis by functioning in the tumour microenvironment; however, role of COUP-TFII colorectal cancer remains unknown. Human colon adenocarcinoma tissues were collected to test expression. Wound-healing and cell invasion assay used evaluate migration cells. related protein expression was assessed immunostaining, immunoblotting real-time PCR assay. Tamoxifen-inducible knockout mice employed...
Our study aims to investigate the effect of colon cancer-associated transcript-1 (CCAT-1) on cancer cells' activity and metabolism under different glucose environments in vitro vivo.The levels proliferation, migration, glucose, lactic acid, metabolism-related enzymes, apoptosis genes, epithelial-mesenchymal transition (EMT) marker proteins, PI3K/Akt/C-MYC pathway CCAT-1-silenced SW620 cells cultured with were tested. Twenty BALB/C nude mice hyperglycemia or normal blood sugar transplanted...
Abstract Aims: To utilize the bioinformatics to analyze differentially expressed genes (DEGs), interaction proteins, perform gene enrichment analysis, protein-protein network (PPI) and map hub between colorectal cancer(CRC) adenocarcinomas(CA). Methods: We analyzed a microarray dataset (GSE32323 GSE4183) from Gene Expression Omnibus (GEO) database. Differentially (DEGs) in tumor tissues non-cancerous were identified using dplyr Venn diagram packages of R Studio software. Functional...