A5071431302- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Alcoholism and Thiamine Deficiency
- Metabolism and Genetic Disorders
- Diet and metabolism studies
- Receptor Mechanisms and Signaling
- Pharmacological Effects and Toxicity Studies
- Neuroendocrine regulation and behavior
- Pharmacological Receptor Mechanisms and Effects
- Electroconvulsive Therapy Studies
- Alcohol Consumption and Health Effects
- Nitric Oxide and Endothelin Effects
- Epilepsy research and treatment
- Nicotinic Acetylcholine Receptors Study
- Attention Deficit Hyperactivity Disorder
- Sleep and Wakefulness Research
- Autism Spectrum Disorder Research
- Schizophrenia research and treatment
- Biochemical Analysis and Sensing Techniques
- Amino Acid Enzymes and Metabolism
- Treatment of Major Depression
- Neurological and metabolic disorders
- Neuroscience of respiration and sleep
- Peroxisome Proliferator-Activated Receptors
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Üsküdar University
2016-2025
Scientific and Technological Research Council of Turkey
2023
Turkish Armed Forces
2005-2015
Kahramanmaraş Sütçü İmam University
2015
Ankara Sosyal Bilimler Üniversitesi
2015
Military Medical Academy
2002-2012
Gülhane Askerî Tıp Akademisi
2001-2009
Hacettepe University
1993-2004
Ankara University
2002
University of North Texas Health Science Center
1997
Prenatal VPA exposure is used to model ASD-like symptoms. Disrupted empathy frequently observed in individuals with ASD, but empathy-like behaviour not well documented animal models. Pregnant Wistar Albino rats were administered either 400 mg/kg or saline i.p. on E12.5. Empathy-like was assessed at P30 and P60 both female male offspring, who also tested for olfactory discrimination, sociability, locomotor activity, pre-pulse inhibition. significantly impaired behaviour, as measured by the...
Clonidine, an alpha-2 adrenergic agonist, is extremely potent antinociceptive agent. However, the therapeutic utility of systemic clonidine for treatment pain limited by centrally mediated side effects including sedation, hypotension and rebound hypertension. Given that adrenoceptors are expressed on peripheral central terminals nociceptive fibers, we administered topically in order to avoid effects. Here, demonstrate topical administration mice (via tail immersion) elicited antinociception...
The aim of the present study was to evaluate effects phosphodiesterase type 5 (PDE5) inhibitory drugs, sildenafil and tadalafil, in ischemia/reperfusion (I/R)-induced oxidative injury fetal rat brain.Timed pregnant adult Wistar rats were randomly assigned following groups (n = 6 for each group): saline + none I/R (1), (2), (3); (4), tadalafil (5) (6). Fetal ischemia induced by clamping utero-ovarian artery bilaterally. Fetuses delivered 268 decapitated. Malondialdehyde (MDA) levels and,...
Agmatine is a guanidine-amine formed by the enzymatic decarboxylation of arginine. has been proposed to be neuromodulator and its downstream derivatives, polyamines, have suggested responsible for sensory gating deficits seen in schizophrenia. In this study, male Wistar rats underwent treatments with agmatine, vehicle or other agents known alter an experimental paradigm prepulse inhibition (PPI) acoustic startle response. Apomorphine (1 mg/kg s.c.), nonselective dopamine agonist disrupt PPI...