A5016544596- Cardiovascular Conditions and Treatments
- Cardiomyopathy and Myosin Studies
- Congenital Heart Disease Studies
- Congenital heart defects research
- Ocular Surface and Contact Lens
- Human-Animal Interaction Studies
- Veterinary Medicine and Surgery
Ghent University
2019-2022
Hypertrophic cardiomyopathy (HCM) is a common and potentially fatal heart disease in many cat breeds. An intronic variant TNNT2, c.95-108G>A, was recently reported as the cause of HCM Maine Coon. The aim this study to determine variant's allele frequency different populations its possible association with HCM. Based on 160 Coon samples collected Belgium, Italy, Sweden USA, estimated be 0.32. Analysis 99 Lives feline whole genome sequencing database showed that TNNT2 also occurs other breeds,...
Corneal sequestra are ophthalmic lesions that remarkably common in Persian, Himalayan and exotic cats. In this study, the genetic aspects of disease were investigated a population cats originating from single cattery. Odds ratios calculated for parents with affected offspring. The heritability (owner-reported) corneal was estimated Markov chain Monte Carlo procedure. Well-phenotyped cases controls used genome-wide association study. Data 692 cattery, which 61 affected, used. Cats two...