- Chronic Obstructive Pulmonary Disease (COPD) Research
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Autoimmune and Inflammatory Disorders
- Intestinal Malrotation and Obstruction Disorders
- Music Therapy and Health
- Retinal Imaging and Analysis
- Gastrointestinal disorders and treatments
- Protease and Inhibitor Mechanisms
- Voice and Speech Disorders
- Esophageal and GI Pathology
- Microscopic Colitis
- Market Dynamics and Volatility
- Gastroesophageal reflux and treatments
- Cystic Fibrosis Research Advances
- Galectins and Cancer Biology
- Child Nutrition and Feeding Issues
- Hormonal Regulation and Hypertension
- Neonatal Respiratory Health Research
- Celiac Disease Research and Management
- Genetic factors in colorectal cancer
- Dermatological and COVID-19 studies
- Inflammatory Bowel Disease
- Congenital Anomalies and Fetal Surgery
- Peptidase Inhibition and Analysis
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2025
Universidade do Porto
2009-2025
Hospitais da Universidade de Coimbra
2009-2019
University of Coimbra
2018
Hospital Pedro Hispano
2005-2014
<b>Rationale:</b> The relationship between bronchiectasis and alpha1-antitrypsin deficiency (AATD) remains unclear. limited number of studies addressing this issue estimate a prevalence in AATD 16.9%-95%, mainly association with the presence emphysema. <b>Aim:</b> Assess characteristics patients AATD. <b>Methods:</b> Retrospective study outpatient clinic Portuguese Hospital, whom CT scan was obtained. Data obtained from patient files. <b>Results:</b> We included 114 patients, 57.9% males,...
Purpose: To analyze the influence of pre-treatment chronicity signs and post-treatment recurrence events in short long-term structural functional outcomes central serous chorioretinopathy (CSC) patients submitted to half-dose photodynamic therapy (PDT), determine profile that recurred after treatment. Methods: A retrospective, observational study included treatment-naive with CSC PDT. Best corrected visual acuity (BCVA), macular thickness (CMT) using OCT retinal sensitivity (RS) assessed by...
Intermediate Alpha1-Antitrypsin Deficiency (A1ATD) is characterized by A1AT levels >50mg/dL in patients with SZ, MZ, SS and MS phenotypes. Despite many published studies, the risk of pulmonary disease these remains controversial. The seems to be greater factor exposure. <b>Objectives:</b> To evaluate existence characteristics intermediate A1ATD its relation smoking occupational Patients attending Outpatient Clinic at our Hospital were included. Data regarding demographics, symptoms,...
<b>Introduction:</b> Alpha<sub>1</sub>-Antytripsin Deficiency (AATD) is one of the most frequent genetic disorders worldwide, but frequently underdiagnosed. In Portugal, there a high prevalence S allele and medium Z allele. Current guidelines for diagnosis management patients with AATD recommend that all COPD should be screened in order to improve diagnosis. <b>Aims Objectives:</b> To evaluate among portuguese patients. <b>Methods:</b> All clinically stable attending Respiratory...
Alpha<sub>1</sub>-antitrypsin deficiency (AATD) is an under-diagnosed hereditary disease. Early diagnosis and adequate management, with lifestyle changes early institution of treatment, improve quality life expectancy. Family screening effective strategy to increase diagnosis. <b>Aim:</b> Evaluate the yield impact family screening. <b>Methods:</b> Retrospective observational study relatives index case AATD carrying alelle Q<sub>0</sub>Ourém, screened at Coimbra Hospital & University...
Neste artigo estudamos pela primeira vez a anomalia de calendário designada efeito semana do ano no mercado acções português. O foi identificado originalmente por Levy e Yagil (2012) refere-se à verificação rendibilidades significativamente diferentes em algumas semanas ano. A amostra utilizada construída partir uma nova base dados histórica que cobre cerca 120 anos história accionista Verificou-se última geraram mais elevadas as restantes Além disso, análise subamostras revelou o evoluiu...