A5083653692- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Retinal Development and Disorders
- Optical Coherence Tomography Applications
- Cerebral Venous Sinus Thrombosis
- Retinal and Macular Surgery
- Ocular Oncology and Treatments
- Syphilis Diagnosis and Treatment
- Botulinum Toxin and Related Neurological Disorders
- Drug-Induced Ocular Toxicity
- Ophthalmology and Eye Disorders
- Hereditary Neurological Disorders
- Lysosomal Storage Disorders Research
- Genetic Neurodegenerative Diseases
- Intraocular Surgery and Lenses
- Cerebrovascular and Carotid Artery Diseases
- Dermatological and Skeletal Disorders
- Imbalanced Data Classification Techniques
- Vascular Tumors and Angiosarcomas
- Meningioma and schwannoma management
- Digital Imaging for Blood Diseases
- Neurological Complications and Syndromes
Hospital de São João
2015-2024
Universidade do Porto
2014-2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024
Faculdade de Medicina do ABC
2014
Diabetic retinopathy (DR) grading is crucial in determining the adequate treatment and follow up of patients, but screening process can be tiresome prone to errors. Deep learning approaches have shown promising performance as computer-aided diagnosis(CAD) systems, their black-box behaviour hinders clinical application. We propose DR$\vert$GRADUATE, a novel deep learning-based DR CAD system that supports its decision by providing medically interpretable explanation an estimation how uncertain...
Proliferative diabetic retinopathy (PDR) is an advanced stage, characterized by neovascularization, which leads to ocular complications and severe vision loss. However, the available DR-labeled retinal image datasets have a small representation of images severest DR grades, thus there lack PDR cases for training grading models. Additionally, criteria labelling these in publicly not always clear, with some do show typical lesions being labeled as due presence photo-coagulation treatment laser...
Background Spectral-domain optical coherence tomography has been used in several neurological conditions, and peripapillary macular measurements have proposed as potential biomarkers these disorders. The aim of this study was to investigate retinal choroidal changes Huntington's disease evaluate any correlation with the stage disease. Methods A cross-sectional observational compared patients controls. Patients were evaluated using Unified Disease Rating Scale. enhanced depth imaging used,...
Syphilis is an infectious disease that can cause a wide variety of ocular signs. One the rarest manifestations syphilis acute syphilitic posterior placoid chorioretinitis (ASPPC). We report on spectral-domain optical coherence tomography (SD-OCT) features case diagnosed with unilateral ASPPC.A 64-year-old man presented sudden loss visual acuity (VA) in right eye. His only clinical sign was large, geographic, yellow-white lesion centered fovea. Our patient studied SD-OCT presentation and...
This paper introduces RetinaCAD, a system, for the fast, reliable and automatic measurement of Central Retinal Arteriolar Equivalent (CRAE), Venular (CRVE), Arteriolar-to-Venular Ratio (AVR) values, as well several geometrical features retinal vasculature. RetinaCAD identifies important landmarks in retina, such blood vessels optic disc, performs artery/vein classification vessel width measurement. The estimation CRAE, CRVE AVR values on 480 images from 120 subjects has shown significant...
An accurate detection of the macular edema (ME) presence constitutes a crucial ophthalmological issue as it provides useful information for identification, diagnosis and treatment different relevant ocular systemic diseases. Serous Retinal Detachment (SRD) is particular type ME, which characterized by leakage fluid that has propensity being accumulated in region. This paper proposes new methodology automatic identification characterization SRD using Optical Coherence Tomography (OCT) images....
Background: Botulism is a rare but potentially lethal disease in which ophthalmic signs and symptoms are among the very earliest manifestations. The aim of this study was to investigate epidemiological clinical features botulism-infected patients admitted general hospital Porto, Portugal. Methods: We performed retrospective chart review all botulism São João Hospital between January 1998 2003. excerpted data on epidemiology, non-ophthalmic manifestations, treatment. Results: identified 18...
This study describes a novel dataset with retinal image quality annotation, defined by three different experts, and presents an inter-observer analysis for assessment that can be used as gold-standard future studies. A state-of-the-art algorithm is also analysed compared against the specialists performance. Results show that, 71% of images present in dataset, experts agree on given label. The results obtained accuracy, specificity sensitivity when comparing one expert another were ranges...
Purpose: This work aimed to longitudinally assess the peripapillary (PPCT) and subfoveal (SFCT) choroidal thickness (CT), in patients diagnosed with central (CRVO) or branch retinal vein occlusions (BRVO), correlating SFCT macular (CMT) PPCT nerve fiber layer (pRNFL). Patients Methods: was a retrospective longitudinal study of 71 eyes from treatment-naïve occlusion (24 CRVO 40 BRVO). Spectral-domain optical coherence tomography (SD-OCT, Spectralis HRA-OCT, Heidelberg) used measure PPCT,...
The authors describe imagiological findings in idiopathic exudative polymorphous vitelliform maculopathy. A 41-year-old woman complained of bilateral blurry vision. Best-corrected visual acuity was 20/20 bilaterally. Bilateral small serous neurosensory detachments the fovea were seen at fundoscopy and confirmed by spectral-domain optical coherence tomography. Fluorescein angiography unremarkable. Indocyanine green presented discrete hyperfluorescent spots on posterior pole. Later, more...
<b><i>Background:</i></b> Central serous chorioretinopathy (CSCR) is a chorioretinal disorder resulting from choroidal hyperpermeability. Its comorbidities as hypertension, coronary disease, and psychological stress, suggest that it might reflect more generalized vascular dysfunction. <b><i>Objectives:</i></b> The aim of the study was to assess cerebrovascular regulation integrity, using cerebral autoregulation (CA), carbon dioxide...
This paper presents an automatic application that provides several retinal image analysis functionalities, namely vessel segmentation, width estimation, artery/vein classification and optic disc segmentation. A pipeline of these methods allows the computation important related indexes, Central Retinal Arteriolar Equivalent (CRAE), Venular (CRVE) Arteriolar-to-Venular Ratio (AVR), as well various geometrical features associated with bifurcations. The results for AVR estimation were assessed...
We report one case of malignant hypertensive retinopathy as a presenting sign fetal death in utero. Ophthalmic examination (including intravenous fluorescein angiography and optical coherence tomography) obstetric systemic evaluation were performed, providing multidisciplinary approach. A 33-year-old overweight woman (body mass index 47 kg/m(2)) with no or ocular known disease was admitted to our emergency department one-week history bilateral vision loss complaints. On examination, best...
Purpose Persistent diabetic macular edema (DME) remains a problem in clinical practice, with many patients having suboptimal response to the standard of care (SOC). Evidence supports long-term efficacy intravitreal fluocinolone acetonide (FAc) implant (ILUVIEN ® ) that have responded sub-optimally, although there is still scarce data from real-world Portuguese practices. We aimed monitor current SOC selected practices prior FAc implantation and then assess effectiveness safety implant....
Central serous chorioretinopathy is a retinal disease in which there leak of fluid into the subretinal space resulting mild to moderate loss visual acuity. Sequences images from fluorescein angiography exam are most times used for analyzing these leaks. This work presents diagnostic aid method detect and characterize progression area along exam, order provide second opinion increase focus speed analysis ophthalmologists. The based on comparative approach by image subtraction between late...
<b><i>Introduction:</i></b> This study aimed to evaluate the longitudinal changes in retinal layer thickness patients treated with hydroxychloroquine without toxicity. <b><i>Methods:</i></b> is a retrospective of taking followed toxicity screening program tertiary hospital between January 2010 and April 2019. Patients who performed 2 optical coherence tomography (OCT) scans at least 1 year apart were included. All subjects suspected or...
Background: Neurofibromatosis Type 1 (NF-1) is a genetic disease affecting the eye, and ocular findings such as Lisch nodules (LN) or optic pathway gliomas (OPGs) are part of its diagnostic criteria. Recent imaging technologies infrared (IR) optical coherence tomography (OCT) have highlighted visualization choroidal focal abnormalities in these patients, even absence other lesions. This study aimed to establish morphological multimodal evaluation patients with NF-1, correlating them central...
Purpose: To report a rare case of exudative maculopathy in patient with facioscapulohumeral muscular dystrophy (FSHD), and its management.Methods: Observational report.Results: A 62-year-old man genetically confirmed FSHD was referred to our department complaining decreased visual acuity his left eye. At presentation, right eye examination unremarkable best-corrected (BCVA) 20/20. Left BCVA 20/100 it presented dense cataract the evidence macular lipid exudation. Cataract surgery combined...
Introduction: Hunter syndrome or mucopolysaccharidosis type II is a rare progressive multi-systemic disorder, caused by an abnormal storage of glycosaminoglycans (GAGs) in almost every cell type, including most ocular tissues [1,2]. Patients have short life expectancy and manifestations can be present early the course disease Purpose: To report fundus autofluorescence tomographic findings syndrome. Methods: A 18-year-old male patient with nyctalopia was submitted to color photography, blue...