Purpose: To report the long-term functional, anatomical and safety outcomes of 0.2 μg/day fluocinolone acetonide 0.19mg in patients with persistent or recurrent diabetic macular edema (DME). Methods: Retrospective, observational, single-center study DME. All received 0.19mg, data were collected at baseline months 1, 3, 6, 12, 24 36 after implantation. Outcomes measured included best-corrected visual acuity (BCVA), central thickness (CMT), intraocular pressure (IOP), outcomes. Results: A...

To systematically compare the efficacy of transepithelial accelerated corneal collagen crosslinking (TE-ACXL) with conventional (C-CXL) in patients progressive keratoconus.Eyes keratoconus who were treated C-CXL (3 mW/cm2 for 30 minutes) compared those underwent TE-ACXL (6 15 minutes). Best-corrected visual acuity (BCVA), keratometry values, thickness, and topometric indexes before CXL, at 2 months, 6 12 months postoperatively.The study enrolled 26 eyes which 16 had 10 C-CXL. Both groups...

Précis: An Ahmed glaucoma valve (AGV) tube in the ciliary sulcus (CS) is safer for endothelium. At 4 years of follow-up, there was a significant decrease endothelial cell count only with anterior chamber (AC) placement. Purpose: Corneal endothelium (CE) damage one most feared long-term complications that can result from drainage devices. Nonetheless, lack studies evaluating longitudinal changes CE cells. This study aims to compare after AGV implantation eyes AC or CS Materials and Methods:...

In January 2013, a 54-year-old pseudophakic woman was referred to the ocular inflammation clinic with diagnosis of panuveitis, already on oral cyclosporine (100 mg/day) since 2010. She monocular patient, left eye eviscerated due trauma and secondary endophthalmitis in 1995. had experienced similar recurring episodes between 2010 2013. Examination revealed best-corrected visual acuity (BCVA) 20/200. The anterior segment presence flare absence cells. Intraocular pressure (IOP) 11 mmHg. Fundus...

Introduction: Recently, vitamin D has gained importance as a diabetes risk modifier. Our aim was to assess the association between serum levels and prevalence of diabetic retinopathy in patients with type 1 diabetes.Material Methods: Retrospective review population followed Portuguese tertiary center. Patients were included if they had an ophthalmological evaluation 25-hydroxyvitamin level determination within same year. Logistic regression analysis used adjust for possible...

"In-the-bag" placement of an IOL is the Holy Grail for any cataract surgeon. However, in absence capsular integrity, alternative surgical options to place must be sought. We aim report clinical outcomes and safety profile scleral-fixated Akreos AO60 intraocular lens implantation using Gore-Tex suture, combined with pars plana vitrectomy.This a single-center, retrospective case series descriptive study. Electronic records all patients subjected scleral fixation Bausch Lomb vitrectomy, between...

Background To characterize the phenotype and genotype of a syndrome associating posterior microphthalmos (PM), retinitis pigmentosa (RP), foveoschisis, foveal hypoplasia (FH) in consanguineous Portuguese family.Materials methods Three siblings were studied underwent comprehensive eye examinations for best-corrected visual acuity, axial length, refractive error, B-mode ultrasound, electroretinography, retinography, fluorescein angiography (FA), kinetic field (VF), optical coherence tomography...

<b><i>Introduction:</i></b> This study aimed to evaluate the longitudinal changes in retinal layer thickness patients treated with hydroxychloroquine without toxicity. <b><i>Methods:</i></b> is a retrospective of taking followed toxicity screening program tertiary hospital between January 2010 and April 2019. Patients who performed 2 optical coherence tomography (OCT) scans at least 1 year apart were included. All subjects suspected or...

Background: Neurofibromatosis Type 1 (NF-1) is a genetic disease affecting the eye, and ocular findings such as Lisch nodules (LN) or optic pathway gliomas (OPGs) are part of its diagnostic criteria. Recent imaging technologies infrared (IR) optical coherence tomography (OCT) have highlighted visualization choroidal focal abnormalities in these patients, even absence other lesions. This study aimed to establish morphological multimodal evaluation patients with NF-1, correlating them central...

Abstract This is a two-center, case series of three patients with postoperative refractory cystoid macular edema (CME) and disruption the iris–lens diaphragm, submitted to scleral fixation fluocinolone acetonide implant. All achieved successful CME reduction visual acuity improvement. The surgical procedure was uneventful in all cases; however, one patient developed hypotony leakage from tunnel, which successfully resolved reinforcement suture injection viscoelastics anterior chamber. No...

We aim to report a case of middle-aged woman with bilateral idiopathic elevated episcleral venous pressure (IEEVP) and its difficulties in the diagnostic approach. Particularly this case, atypical feature ocular hypertension without glaucomatous optic nerve damage may be misleading. present 66-year-old longstanding "red eyes." Clinical findings included vessel engorgement tortuosity raised intraocular open iridocorneal angles. Despite hypertension, neuropathy was absent confirmed by normal...

We report the clinical phenotype and genetic findings of two variants in PDE6C underlying achromatopsia (ACHM). Four patients with variant c.1670G>A exon 13 gene were identified. Additionally, one had compound heterozygous genotype, gene, a c.2192G>A 18 13. All presented symptomatic triad decreased visual acuity, severe photophobia, colour vision disturbances. SD-OCT showed an absence ellipsoid zone, creating optically empty cavity at fovea three patients. The patient genotype more...

Introduction: Lamellar Keratoplasty (LK) allows the selective replacement of altered corneal layers. It is associated with fewer complications, lower rejection rate and better functional results, when compared penetrant keratoplasty (PK). LK started to be performed in Centro Hospitalar Sao Joao (CHSJ) 2009, significant evolution number techniques recently. The objective this study was evaluate surgical main indications for transplantation CHSJ last 8 years.   Material...

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The aim of this study was to evaluate whether the coronavirus disease 19 (COVID-19) pandemic resulted in undertreatment and subsequent loss visual acuity (VA) patients with macular neovascularization (MNV) or retinal vein occlusion (RVO) regularly treated intravitreal antivascular endothelial growth factor injections.Single-center, retrospective scheduled for treatment between March June 1, 2020, national mandatory quarantine period. Patients' demographics, VA, during period were reviewed...