A5075549584- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Retinal Development and Disorders
- Optical Coherence Tomography Applications
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Ocular Oncology and Treatments
- Ophthalmology and Eye Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Dermatological and Skeletal Disorders
- Vascular Malformations Diagnosis and Treatment
- Breastfeeding Practices and Influences
- Actinomycetales infections and treatment
- Infectious Diseases and Mycology
- Autoimmune Neurological Disorders and Treatments
- Insects and Parasite Interactions
- Cellular Mechanics and Interactions
- Laser-Plasma Interactions and Diagnostics
- Neurosurgical Procedures and Complications
- Acne and Rosacea Treatments and Effects
- Cerebrovascular and genetic disorders
- Angiogenesis and VEGF in Cancer
Universidade Nova de Lisboa
2018-2025
Hospital Garcia de Orta
2023-2025
Câmara Municipal de Almada
2024-2025
Vitreous Retina Macula Consultants of New York
2020-2025
University of Coimbra
2024
New York University
2022-2023
Centre Ophtalmologique d'Imagerie et de Laser
2018-2020
Clínica e Instituto de Oftalmologia Ivo Corrêa Meyer
2018-2020
Nova Medical (United States)
2020
This study aims to characterize the clinical spectrum and genetic landscape of IRDs in Portugal. Multicentre, cross-sectional, cohort comprising consecutive patients with a diagnosis IRD available results, enroled IRD-PT registry (retina.com.pt). Among 1369 from 1125 families, most frequently observed phenotype was non-syndromic retinitis pigmentosa (40.8%). A genetically confirmed achieved 72.3% families. Consanguinity one-fifth cases, contributing higher frequency homozygous variants...
To evaluate on optical coherence tomography angiography (OCT-A), the predictive role of different qualitative findings choroidal neovascularisations (CNV) in assessing status exudative age-related macular degeneration (eAMD) and to develop a potential model predict CNV activity.Retrospective review multimodal imaging records patients with eAMD obtained during treatment for type 1 or 2 CNV. The analysis CNVs OCT angiograms assessed presence absence tiny branching vessels, loops, peripheral...
To characterize quantitative optical coherence tomography angiography (OCT-A) parameters in active neovascular age-related macular degeneration (nAMD) patients under treatment and remission nAMD patients.Retrospective, cross-sectional study.One hundred four of whom 72 were Group 1 (active nAMD) 32 2 (remission based on SD-OCT (Spectral Domain OCT) qualitative morphology.This study was conducted at the Centre Ophtalmologique de l'Odeon between June 2016 December 2017. Eyes analyzed using...
To investigate intraretinal neovascularization and microvascular anomalies by correlating in vivo multimodal imaging with corresponding ex histology a single patient.A case study comprising clinical from community-based practice, histologic analysis at university-based research laboratory (clinicopathologic correlation).A White woman her 90s treated numerous intravitreal anti-VEGF injections for bilateral type 3 macular (MNV) secondary to age-related degeneration (AMD).Clinical comprised...
Purpose: The purpose of this study was to identify a precise location deep capillary plexus (DCP) injury in acute macular neuroretinopathy (AMN) lesions using multimodal imaging. Methods: En face structural optical coherence tomography (OCT) images were manually segmented delineate outer retinal AMN involving the ellipsoid zone and interdigitation zone. lesion centroid calculated, image distortion applied correct for Henle fiber layer (HFL) length orientation. resulting registered with...
By validating optical coherence tomography angiography (OCTA) in the analysis of type 3 macular neovascularization secondary to age-related degeneration, overall value clinical OCTA for disease observation, diagnosis, and staging is increased.
Purpose: To characterize macular blood flow connectivity in vivo using high-resolution optical coherence tomography (HighRes OCT). Methods: Cross-sectional, observational study. Dense (6-µm interscan distance) perifoveal HighRes OCT raster scans were performed on healthy participants. mitigate the limitations of projection-resolved OCT-angiography, and structural data used to observe vascular structures superficial complex (SVC) deep complex. Vascular segmentation rendering Imaris 9.5...
To evaluate the long-term progression of quiescent type 1 choroidal neovascularisation (CNV) associated with age-related macular degeneration (AMD) or pachychoroid disease.All cases CNV a minimum follow-up 12 months seen at Department Ophthalmology University Paris Est, Creteil and Centre Ophtalmologique de l'Odeon, Paris, between June 2009 December 2018 were retrospectively reviewed. Optical coherence tomography angiography (OCT-A) eyes not showing activation during 24 was evaluated for...
To investigate genotype-phenotype correlations in ABCA4-associated retinopathy and further validate a recently proposed correlation model. Multicentric, cross-sectional cohort study. Consecutive patients with genetically confirmed from three Portuguese centres were included. Patients categorized into distinct phenotype groups according to the degree of hypoautofluorescence retinal background appearance ultra-widefield fundus autofluorescence (UW-FAF) imaging. Genotype classification was...
Purpose: To assess the long-term evolution of treatment-naive quiescent choroidal neovascularization (CNV), in age-related macular degeneration (AMD), to identify predictive activation biomarkers. Methods: Patients with CNV underwent a comprehensive ophthalmological examination, including fluorescein and indocyanine green angiographies, structural optical coherence tomography (OCT), OCT angiography. Qualitative quantitative analyses angiography images were performed during study period. At...
To study the association between assessment of central macular vascular layers by optical coherence tomography angiography (OCT-A) and peripheral nonperfusion evaluated fluorescein (FA) in patients with retinal venous occlusion (RVO).Retrospective review RVO without edema. Patients underwent a comprehensive ophthalmic examination including FA, spectral-domain OCT, OCT-A. Significant ischemia was defined as areas superior or equal to equivalent one quadrant on FA. Vascular density (VD) foveal...
To compare optical coherence tomography-angiography (OCT-A) performed during physical exercise (stress OCT-A) to the basal examination (rest in imaging of choroidal neovascularization (CNV) patients with chronic central serous chorioretinopathy (CSCR).Prospective, cohort study.This multicenter study included 29 consecutive CSCR and flat irregular pigment epithelium detachments (FIPEDs). All underwent rest stress OCT-A (i.e., hand-grip test [HGT]). Systemic hemodynamic data were recorded...
Purpose: To characterize macular blood flow connectivity using volume rendering of dense B-scan (DB) optical coherence tomography angiography (OCTA) data. Methods: This was a prospective, cross-sectional, observational study. DB OCTA perifoveal scans were performed on healthy subjects the Spectralis HRA+OCT2. A volumetric projection artifact removal algorithm and customized filters applied to raw voxel Volume workflow Imaris 9.5 software. Vascular graphs obtained from angiographic data...
To compare quantitative optical coherence tomography angiography parameters between treatment-naïve quiescent macular neovascularizations (MNVs) and previously treated nonexudative Type 1 MNVs, in patients with age-related degeneration.The eyes included the study were analyzed by fluorescein angiography, indocyanine green spectral-domain tomography, angiography. According to their medical history multimodal imaging evaluation, MNVs divided into 2 groups: 1) MNVs; 2) MNVs. Quantitative...
In this paper, we evaluate the different thresholding strategies that have been used for quantification of choriocapillaris (CC) and explore their repeatability interchangeability measurements resulting from its application.