Pedro Gutiérrez‐Castrellón

ORCID: 0000-0002-9885-9635
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About
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Research Areas
  • Infant Health and Development
  • Viral gastroenteritis research and epidemiology
  • Clinical Nutrition and Gastroenterology
  • Respiratory and Cough-Related Research
  • Gut microbiota and health
  • Child Nutrition and Feeding Issues
  • Parasitic Infections and Diagnostics
  • Infant Nutrition and Health
  • Pediatric health and respiratory diseases
  • COVID-19 Clinical Research Studies
  • Erythrocyte Function and Pathophysiology
  • Biochemical and Molecular Research
  • Health and Medical Education
  • Streptococcal Infections and Treatments
  • Child and Adolescent Health
  • Clostridium difficile and Clostridium perfringens research
  • Obesity, Physical Activity, Diet
  • Neonatal and Maternal Infections
  • Long-Term Effects of COVID-19
  • Toxoplasma gondii Research Studies
  • Ethics and bioethics in healthcare
  • Breastfeeding Practices and Influences
  • Helicobacter pylori-related gastroenterology studies
  • Digestive system and related health
  • Pneumocystis jirovecii pneumonia detection and treatment

Universidad Juárez del Estado de Durango
2025

Hospital General Dr. Manuel Gea Gonzalez
2014-2023

GEDI Gruppo Editoriale (Italy)
2023

Secretaria de Salud
2003-2020

Hospital Materno-Infantil
2020

Mexican Academy of Sciences
2020

Technological University of Mexico
2016-2018

Institute of Child and Mother Health
2017

Instituto Nacional de Perinatología
2012-2014

Universidad La Salle
2014

Intestinal bacteria may influence lung homeostasis via the gut-lung axis. We conducted a single-center, quadruple-blinded, randomized trial in adult symptomatic Coronavirus Disease 2019 (Covid19) outpatients. Subjects were allocated 1:1 to probiotic formula (strains Lactiplantibacillus plantarum KABP022, KABP023, and KAPB033, plus strain Pediococcus acidilactici KABP021, totaling 2 × 109 colony-forming units (CFU)) or placebo, for 30 days. Co-primary endpoints included: i) proportion of...

10.1080/19490976.2021.2018899 article EN cc-by-nc Gut Microbes 2022-01-11

Mexico City children are chronically exposed to significant concentrations of air pollutants and exhibit chronic respiratory-tract inflammation. Epidemiological, controlled human exposures, laboratory-based animal models, in vitro/in vivo studies have shown that inflammatory, endothelial dysfunction, damage mediators upregulated upon exposure particulate matter (PM). Endothelial dysfunction is a critical event cardiovascular disease. The focus this work was investigate whether ambient...

10.1080/08958370701864797 article EN Inhalation Toxicology 2008-01-01

To evaluate whether daily administration of Lactobacillus reuteri DSM 17938 reduces the frequency and duration diarrheal episodes other health outcomes in day school children Mexico.Healthy (born at term, aged 6-36 months) attending care centers were enrolled this randomized, double-blind, placebo-controlled trial. They received L (dose 10(8) colony-forming unit; n = 168) or identical placebo (n by mouth, for 3 months, after which they followed-up a further months without...

10.1542/peds.2013-0652 article EN PEDIATRICS 2014-03-18

The recent advisory issued by the United States Food and Drug Administration, cautioning against routine administration of probiotics in preterm neonates, has sparked a lively debate within scientific community. This commentary presents perspective from members Special Interest Group on Gut Microbiota Modifications European Society for Paediatric Gastroenterology, Hepatology Nutrition (ESPGHAN) other authors who contributed to ESPGHAN position paper infants, as well representatives...

10.1002/jpn3.12204 article EN cc-by-nc-nd Journal of Pediatric Gastroenterology and Nutrition 2024-04-04

Necrotizing fasciitis (NF) is a severe, life-threatening soft tissue infection. General features and risk factors for fatal outcome in children are not well known.To characterize the of NF outcome.Retrospective, comparative, observational, longitudinal trial.Dermatology department tertiary care pediatric hospital.All patients with clinical and/or histopathological diagnosis seen from January 1, 1971, through December 31, 2000.Incidence, age, sex, number location lesions, preexisting...

10.1001/archderm.138.7.893 article EN Archives of Dermatology 2002-07-01

ABSTRACT Objective To characterize the clinical features, response to therapy, evolution and prognosis of cutaneous mastocytosis in children. Background Mastocytosis children, instead being induced by a potentially oncogenic c‐kit mutation is probably clonal disease with benign prognosis. Methods The clinicopathological treatment were analysed 71 children mastocytosis. Results There 53 (75%) cases urticaria pigmentosa, 12 (17%) mastocytoma, six (8%) diffuse In 92% onset was first year life....

10.1111/j.1468-3083.2004.00830.x article EN Journal of the European Academy of Dermatology and Venereology 2004-04-15

Background. Skin diseases among pediatric patients differ from those in adults. Epidemiological studies are scarce, and performed Mexican population date back thirty years. It is likely that these might have changed their frequency. Material Methods. Retrospective study first-time referred to a dermatology service between January 1994 December 2003. Demographics diagnosis were recorded compared with the results of previous same institution. Results. We included 5250 (52.55% female, 47.47%...

10.5402/2012/351603 article EN ISRN Dermatology 2012-10-14

Abstract Giardiasis, the most prevalent intestinal parasitosis in humans, is caused by Giardia lamblia . Current drug therapies have adverse effects on host, and resistant strains against these drugs been reported, demonstrating an urgent need to design more specific antigiardiasic drugs. ATP production G. depends mainly glycolysis; therefore, all enzymes of this pathway proposed as potential targets. We previously demonstrated that glycolytic enzyme triosephosphate isomerase from (GlTIM),...

10.1002/prot.23100 article EN Proteins Structure Function and Bioinformatics 2011-06-17

Giardiasis is highly prevalent in the developing world, and treatment failures with standard drugs are common. This work deals proposal of omeprazole as a novel antigiardial drug, focusing on giardial glycolytic enzyme used to follow cytotoxic effect at molecular level. We recombinant technology inactivation demonstrate capacity inactivate triosephosphate isomerase, no adverse effects its human counterpart. To establish specific target enzyme, we single mutants every cysteine residue...

10.1128/aac.02900-14 article EN Antimicrobial Agents and Chemotherapy 2014-09-16

Background: The importance of prebiotics consumption is increasing all over the world due to their beneficial effects on health. Production better from endemic plants raises possibilities enhance nutritional in vulnerable population groups. Fructans derived Agave Plant have demonstrated safety and efficacy as animal models. Recently, humans two fructans obtained tequilana (Metlin® Metlos®) was demonstrated. Methods: This study aimed demonstrate Metlin® Metlos® newborns a randomized, double...

10.3390/nu7115442 article EN Nutrients 2015-10-29

Synbiotics are a mixture comprising of live microorganisms and substrate(s) selectively utilized by host that confers health benefit on the host. There is an increasing number studies investigating their role in different diseases disorders.The purpose this article to provide recommendations for use synbiotics management pediatric gastrointestinal disorders. The developed ESPGHAN Special Interest Group Gut Microbiota Modifications.From existing literature databases, we searched appraised all...

10.1097/mpg.0000000000003568 article EN Journal of Pediatric Gastroenterology and Nutrition 2022-07-28

OBJECTIVES: Across guidelines, protein dosing for critically ill patients with obesity varies considerably. The objective of this analysis was to evaluate whether population would benefit from higher doses protein. DESIGN: A post hoc subgroup the effect in high nutritional risk (EFFORT Protein): an international, multicenter, pragmatic, registry-based randomized trial. SETTING: Eighty-five adult ICUs across 16 countries. PATIENTS: Patients defined as a body mass index (BMI) greater than or...

10.1097/ccm.0000000000006117 article EN Critical Care Medicine 2023-11-06

Background Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder in adults. Systematic reviews with meta-analyses have demonstrated the efficacy and safety of probiotics improving symptoms IBS. Aim The aim study was to demonstrate Limosilactobacillus reuteri ( L. ) DSM 17938 combined ATCC PTA 6475 regarding associated IBS Methods A randomized, double-blind, placebo-controlled clinical trial conducted 140 adults aged 18 years 65 diagnosis (based on Rome IV criteria)....

10.3389/fgstr.2023.1296048 article EN cc-by Frontiers in Gastroenterology 2024-01-04

Among 27 pediatric patients with a clinicopathologic diagnosis of discoid lupus erythematosus (DLE), 15 had localized cutaneous lesions and 12 disseminated lesions. During mean follow-up period 36 months, seven (26%) developed systemic (SLE). Four these were less than 10 years age. No correlation was found between evolution to SLE. Three four positive family history for rheumatoid disease SLE (p < 0.05). Hyperpigmentation significantly more frequent 0.04) in children There female...

10.1046/j.1525-1470.2003.20201.x article EN Pediatric Dermatology 2003-03-01

Dermatitis artefacta is a factitious disorder in which there deliberate conscious production of skin lesions. There are only few reports that evaluate instances dermatitis the pediatric population. The aim this retrospective study was to assess characteristics patients with who were seen at National Institute Pediatrics Mexico City. records all diagnosed from January 1980 December 1999 analyzed. 29 (25 females, 4 males). upper limbs and face most commonly involved areas. Superficial erosions...

10.1111/j.0736-8046.2004.21303.x article EN Pediatric Dermatology 2004-05-01
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