- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
- Systemic Lupus Erythematosus Research
- Immune cells in cancer
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Immune Cell Function and Interaction
- Graphene and Nanomaterials Applications
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Extracellular vesicles in disease
- Atherosclerosis and Cardiovascular Diseases
- Galectins and Cancer Biology
- Helicobacter pylori-related gastroenterology studies
- Pregnancy and preeclampsia studies
- Peripheral Artery Disease Management
- Pediatric Urology and Nephrology Studies
- Curcumin's Biomedical Applications
- Inflammation biomarkers and pathways
- Adolescent Sexual and Reproductive Health
- Consumer Attitudes and Food Labeling
- Adipokines, Inflammation, and Metabolic Diseases
- Selenium in Biological Systems
- Berberine and alkaloids research
Mashhad University of Medical Sciences
2014-2024
Shiraz University of Medical Sciences
2016
Abstract Systemic lupus erythematosus (SLE) is known as an autoimmune disorder that characterized by the breakdown of self‐tolerance, resulting in disease onset and progression. Macrophages have been implicated a factor development SLE through faulty phagocytosis dead cells or imbalanced M1/M2 ratio. The study aimed to investigate immunomodulatory effects Lactobacillus delbrueckii rhamnosus on M1 M2 macrophages new case patients. For this purpose, blood monocytes were collected from patients...
Abstract Smart scaffolds have a great role in the damaged tissue reconstruction. The aim of this study was developing scaffold that addition to its fiber's topography has also content micro‐RNAs (miRNAs), which play regulatory during osteogenesis. In study, we inserted two important miRNAs, including miR‐22 and miR‐126 electrospun polycaprolactone (PCL) nanofibers after characterization, osteoinductivity fabricated investigated by evaluating osteogenic differentiation potential induced...
Repairing the lost or damaged mandible is very difficult and time-consuming, so there a great hope for tissue engineering to accelerate it. At present study, electrospinning was applied fabricate polyvinylidene fluoride (PVDF) PVDF-polyaniline (PANI) composite scaffolds. In addition, extremely low frequency pulsed electromagnetic field (PEMF) treating stem cells derived from dental pulp (DPSCs) when cultured on nanofibrous Osteoinductive property of fabricated PVDF, PVDF-PANI scaffold at...
Today, composite scaffolds fabricated by natural and synthetic polymers have attracted a lot of attention among researchers in the field tissue engineering, given their combined properties that can play very useful role repairing damaged tissues. In current study, aloe vera-derived gel-blended poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofibrous scaffold was electrospinning, then, PHBV gel characterized scanning electron microscope, protein adsorption, cell attachment, tensile...
Abstract In recent decades, tissue engineering has been the most contributor for introducing 2D and 3D biocompatible osteoinductive scaffolds as bone implants. Polyvinylidene fluoride (PVDF), due to unique mechanical strength piezoelectric properties, can be a good choice making bioimplant. present study, PVDF nanofibers film were fabricated scaffolds, then, osteogenic differentiation potential of human induced pluripotent stem cells (iPSCs) was investigated when grown on by evaluating...
Systemic lupus erythematosus (SLE) is a complex autoimmune disease recognized by elevated activity of cells, loss tolerance, and decreased regulatory T cells producing inhibitory cytokines. Despite many efforts, the definitive treatment for has not been fully understood. Curcumin (CUR) berberine (BBR) have significant immunomodulatory roles anti-inflammatory properties that demonstrated in various studies. This study aimed to investigate CUR BBR on human monocyte-derived dendritic (DCs) with...
Preeclampsia is the most common serious disorder during pregnancy and studies show several immune-related processes in its pathophysiology. The role of cytokines their expression remains controversial this field. One interest recent has been TNF-α, which shown to have a higher level maternal plasma preeclamptic women.This study was designed evaluate TNF-α polymorphism at position -238 risk developing preeclampsia pregnancy.One hundred fifty three cases 140 healthy pregnant women were...
Abstract Background and Aim In recent years, vitamin D deficiency has become a major worldwide problem that can exert harmful effects. The aim of the present study was to evaluate sex‐ age‐related prevalence in people from Mashhad, northeastern Iran. Methods this cross‐sectional conducted over period 1 year (2015‐2016), 7504 subjects who referred Mashhad medical centers were randomly enrolled study. population divided into four groups based on sex age, as following: group 1, 6 18 years; 2,...
Numerous bioactive growth factors and cytokines in platelet-rich plasma (PRP) have recently made it an attractive biomaterial for therapeutic purposes. These the potential to regenerate injured tissues. The aim of this study was investigate effects PRP hepatotoxic animal model. Hepatotoxicity induced rats by oral administration 4 mL/kg/week CCl4 diluted 1:1 corn oil 10 weeks. To confirm hepatotoxicity, 24 h after last administration, blood samples were collected via cardiac puncture assess...