A5027836824- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Radiation Detection and Scintillator Technologies
- Ultrasound and Hyperthermia Applications
- Advanced MRI Techniques and Applications
German Cancer Research Center
2022-2023
Heidelberg University
2022
Heidelberger Institut für Radioonkologie
2022
Purpose. Improvements in image-guided radiotherapy (IGRT) enable accurate and precise treatment of moving tumors the abdomen while simultaneously sparing healthy tissue. However, lack validation tools for newly developed MR-guided hybrid devices such as MR-Linac is an open issue. This study presents a custom abdominal phantom with respiratory organ motion multimodal imaging contrast to perform end-to-end tests IGRT planning scenarios.Methods. The contains deformable anatomically shaped liver...
Objective. Carbon ion radiotherapy is a promising radiation technique for malignancies like pancreatic cancer. However, organs' motion imposes challenges achieving homogeneous dose delivery. In this study, an anthropomorphicPancreasPhantom forIon-beamTherapy (PPIeT) was developed to simulate breathing and gastrointestinal during radiotherapy.Approach. The phantom contains pancreas, two kidneys, duodenum, spine spinal cord. shell of the organs 3D printed filled with agarose-based mixtures....
Over recent decades, stereotactic body radiotherapy has garnered increasing popularity. Unfortunately, conventional preclinical 2D in vitro models are often insufficient for studying effects. Therefore, this study, we developed a novel anthropomorphic liver phantom, which simulates the relevant hepatocellular carcinoma (HCC) tumor microenvironment and spatial organization. The phantom was 3D printed, filled with tissue-mimicking agarose mixture, designed to fit ten microfluidic chips (MCs),...