A5011464627- Traumatic Brain Injury and Neurovascular Disturbances
- Cellular Mechanics and Interactions
- Renal cell carcinoma treatment
- Renal and Vascular Pathologies
- Topic Modeling
- Soft Robotics and Applications
- 3D Printing in Biomedical Research
- Machine Learning in Healthcare
- Natural Language Processing Techniques
- Traumatic Brain Injury Research
- S100 Proteins and Annexins
- Pancreatic and Hepatic Oncology Research
- Radiation Dose and Imaging
- Radiology practices and education
- Thyroid and Parathyroid Surgery
- Modular Robots and Swarm Intelligence
- Robot Manipulation and Learning
- Robotic Locomotion and Control
- Tissue Engineering and Regenerative Medicine
- Urinary and Genital Oncology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Teleoperation and Haptic Systems
- Cellular transport and secretion
- Sarcoidosis and Beryllium Toxicity Research
- Robotics and Automated Systems
Brigham and Women's Hospital
2019-2025
Harvard University
2011-2025
Wyss Institute for Biologically Inspired Engineering
2012-2015
California Institute of Technology
2006
Jet Propulsion Laboratory
2005
Vasospasm of the cerebrovasculature is a common manifestation blast-induced traumatic brain injury (bTBI) reported among combat casualties in conflicts Afghanistan and Iraq. Cerebral vasospasm occurs more frequently, with earlier onset, bTBI patients than other TBI modes, such as blunt force trauma. Though usually associated presence subarachnoid hemorrhage (SAH), SAH not required for bTBI, which suggests that unique mechanics blast could potentiate accounting increased incidence. Here,...
In vitro models of ischemia have not historically recapitulated the cellular interactions and gradients molecules that occur in a 3D tissue. This work demonstrates paper-based culture system mimics some among populations cells heart during ischemia. Multiple layers paper containing cells, suspended hydrogels, are stacked to form layered model Mass transport oxygen glucose into this can be modulated induce an ischemic environment bottom stack. stress induces cardiomyocytes at stack secrete...
Over the past decade, investigators have attempted to establish pathophysiological mechanisms by which non-penetrating injuries damage brain. Several studies implicated either membrane poration or ion channel dysfunction pursuant neuronal cell death as primary mechanism of injury. We hypothesized that traumatic stimulation integrins may be an important etiological contributor mild Traumatic Brain Injury. In order study effects forces at cellular level, we utilized two hierarchical, in vitro...
Abstract Although pathological changes in axonal morphology have emerged as important features of traumatic brain injury (TBI), the mechanical vulnerability microcompartment relative to cell body is not well understood. We hypothesized that soma and neurite microcompartments exhibit distinct behaviors, rendering axons more sensitive a injury. In order test this assumption, we combined protein micropatterns with magnetic tweezer rheology probe viscoelastic properties neuronal...
Background Adrenal masses are common, but radiology reporting and recommendations for management can be variable. Purpose To create a machine learning algorithm to segment adrenal glands on contrast-enhanced CT images classify as normal or mass-containing assess performance. Materials Methods This retrospective study included two groups of abdominal examinations (development data set secondary test set). in the development were manually segmented by radiologists. Images both classified...
Purpose Introduces the Lemur IIb robot which allows investigation of technical hurdles associated with free climbing in steep terrain. These include controlling distribution contact forces during motion to ensure holds remain intact and enable mobility through over‐hangs. Efforts also can be applied further in‐situ characterization terrain, such as testing strength developing models individual a terrain map. Design/methodology/approach A system was designed integrated. Climbing end‐effector...
Abstract A 68-year-old woman presented with chest pain and shortness of breath. Imaging revealed a left hilar mass biopsy-proven as small cell cancer. Concurrently, macroscopic fat-containing renal lesion consistent an angiomyolipoma was observed. Systemic therapy achieved stability in the lungs bones, palliative radiation targeted hilum. However, progressive lung disease brain metastases necessitated stereotactic radiosurgery for lesions. Notably, exhibited increased soft tissue component...
Electronic Health Records (EHRs) provide vital contextual information to radiologists and other physicians when making a diagnosis. Unfortunately, because given patient's record may contain hundreds of notes reports, identifying relevant within these in the short time typically allotted case is very difficult. We propose evaluate models that extract text snippets from patient records rough summary intended aid considering one or more diagnoses. This hard direct supervision (i.e., physician...
Future NASA's missions include the search for past and existing life in Universe evidence on how planets Solar system formed evolved. In order to fulfill these goals sampling systems that meet stringent requirements of various environments are required be developed. To support objectives an ultrasonic/sonic driller/corer (USDC) device has been developed at Jet Propulsion Laboratory (JPL) allow drilling coring rocks in-situ planetary analysis [Bar-Cohen et al, 2001]. The site location method...
Intercostal Brown Adipose Tissue on FDG PET/CTBorna E. Dabiri, MD, PhD1 and Heather A. Jacene, MD12Audio Available | Share