- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Radiation Dose and Imaging
- MRI in cancer diagnosis
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Liver Disease Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Radiology practices and education
- Advanced X-ray and CT Imaging
- Pleural and Pulmonary Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal and related cancers
- Inflammatory Bowel Disease
- Liver Disease and Transplantation
- Adrenal and Paraganglionic Tumors
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Microscopic Colitis
- Gallbladder and Bile Duct Disorders
Brigham and Women's Hospital
2015-2024
Harvard University
2015-2024
Harvard Affiliated Emergency Medicine Residency
2021
Lemuel Shattuck Hospital
2017-2021
IGI Technologies (United States)
2021
Chestnut Hill College
2016-2020
Dana-Farber Cancer Institute
2018
Beth Israel Deaconess Medical Center
2012
Harvard University Press
2010
University of California San Francisco Medical Center
1992
Clinically relevant subtypes exist for pancreatic ductal adenocarcinoma (PDAC), but molecular characterization is not yet standard in clinical care. We implemented a biopsy protocol to perform time-sensitive whole-exome sequencing and RNA patients with advanced PDAC. Therapeutically genomic alterations were identified 48% (34/71) pathogenic/likely pathogenic germline 18% (13/71) of patients. Overall, 30% (21/71) enrolled experienced change management as result data. Twenty-six had and/or...
To determine the sensitivity and specificity of magnetic resonance (MR) imaging for depicting pancreatic small, functional islet cell tumors minimum number sequences expedient diagnosis.Twenty-eight patients clinically suspected to have underwent T1- T2-weighted spin-echo (SE) MR with without fat suppression, fast SE imaging, spoiled gradient-echo (GRE) before after injection gadopentetate dimeglumine. Sensitivity, specificity, best definitive diagnosis were determined.MR images depicted...
To establish the feasibility of performing combined positron emission tomography (PET)/computed (CT)-guided biopsy abdominal masses by using previously acquired PET/CT images registered with intraprocedural CT images.In this HIPAA-compliant institutional review board-approved study, 14 patients underwent clinically indicated percutaneous (mean size, 3.3 cm; range, 1.2-5.0 cm) in liver (n = 6), presacral soft tissue 3), retroperitoneal lymph nodes 2), spleen and pancreas 1). obtained no more...
Percutaneous Image-Guided Cryoablation of Hepatic Tumors: Single-Center Experience With Intermediate to Long-Term OutcomesDaniel I. Glazer1, Servet Tatli2, Paul B. Shyn1, Mark G. Vangel3, Kemal Tuncali1 and Stuart Silverman1Audio Available | Share
Lung ultrasound (LUS) is an important imaging modality used by emergency physicians to assess pulmonary congestion at the patient bedside. B-line artifacts in LUS videos are key findings associated with congestion. Not only can interpretation of be challenging for novice operators, but visual quantification B-lines remains subject observer variability. In this work, we investigate strengths and weaknesses multiple deep learning approaches automated detection localization videos. We curate...
The purpose of this study was to determine which MRI features observed 24 hours after technically successful percutaneous cryoablation liver tumors predict subsequent local tumor progression and describe the evolution imaging findings cryoablation.Thirty-nine adult patients underwent imaging-guided 54 (hepatocellular carcinoma, 8; metastases, 46). pertaining tumor, ablation margin, surrounding treatment were assessed independently by two readers. Fisher exact or Wilcoxon rank sum tests...
Purpose: Advancements in and adoption of consumer virtual reality (VR) are currently being propelled by numerous upcoming devices such as the Oculus Rift. Although applications growing around entertainment field, wide-spread VR opens up potential for other that may have been unfeasible with past implementations VR. A environment provide an equal or larger screen area than what is provided use multiple conventional displays while remaining comparatively cheaper more portable making it...
Background Percutaneous ablation for cT1 renal cell carcinoma (RCC) remains underused, partially because of heterogeneous and limited long-term outcomes data assessing recent cryoablation methods. Purpose To report intermediate- to image-guided percutaneous RCC compare CT versus MRI guidance. Materials Methods This HIPAA-compliant retrospective single-institution study assessed patients who underwent solitary pathology-proven between August 2000 July 2017. Tumors (cT1a, n = 282; cT1b, 25;...
BACKGROUND. To our knowledge, outcomes between percutaneous microwave ablation (MWA) and cryoablation of sarcoma lung metastases have not been compared. OBJECTIVE. The purpose this study was to compare technical success, complications, local tumor control, overall survival (OS) after MWA versus metastases. METHODS. This retrospective cohort included 27 patients (16 women, 11 men; median age, 64 years; Eastern Cooperative Oncology Group performance score, 0-2) who, from 2009 2021, underwent...
The purpose of this study was to evaluate the diagnostic efficacy low-dose, combined <sup>18</sup>F-FDG PET/CT enterography (PET/CTE), compared with CT (CTE) alone, in assessment patients Crohn disease. <b>Methods:</b> Thirteen disease were prospectively enrolled pilot and underwent abdominal–pelvic PET/CTE using neutral oral intravenous contrast medium. effective dose from 17.7 mSv for first 4 8.31 last 9 patients. Six surgical resection bowel, 7 colonoscopy biopsies within 27 d (mean, 12...