- Pneumonia and Respiratory Infections
- Emergency and Acute Care Studies
- Respiratory viral infections research
- Healthcare Policy and Management
- Neonatal Respiratory Health Research
- Neonatal Health and Biochemistry
- Electrolyte and hormonal disorders
- Bacterial Infections and Vaccines
- Streptococcal Infections and Treatments
- Child and Adolescent Health
- Adolescent and Pediatric Healthcare
- Hospital Admissions and Outcomes
- Healthcare cost, quality, practices
- Neonatal and Maternal Infections
- Childhood Cancer Survivors' Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Herpesvirus Infections and Treatments
- Ultrasound in Clinical Applications
- Nosocomial Infections in ICU
- Pediatric Urology and Nephrology Studies
- Sepsis Diagnosis and Treatment
- Orthopedic Infections and Treatments
- Antibiotic Use and Resistance
- Pharmaceutical studies and practices
University of Cincinnati Medical Center
2016-2025
Cincinnati Children's Hospital Medical Center
2016-2025
University of Cincinnati
2016-2025
Global Hospitals
2014-2025
Office of Infectious Diseases
2003-2024
Florida College
2024
University of Florida
2023-2024
Children's Medical Center
2020-2024
The Research Council
2024
Community Eye Care Foundation
2024
Evidenced-based guidelines for management of infants and children with community-acquired pneumonia (CAP) were prepared by an expert panel comprising clinicians investigators representing community pediatrics, public health, the pediatric specialties critical care, emergency medicine, hospital infectious diseases, pulmonology, surgery. These are intended use primary care subspecialty providers responsible otherwise healthy CAP in both outpatient inpatient settings. Site-of-care management,...
<h3>Importance</h3> In the US, states enacted nonpharmaceutical interventions, including school closure, to reduce spread of coronavirus disease 2019 (COVID-19). All 50 closed schools in March 2020 despite uncertainty if closure would be effective. <h3>Objective</h3> To determine and its timing were associated with decreased COVID-19 incidence mortality. <h3>Design, Setting, Participants</h3> US population–based observational study conducted between 9, 2020, May 7, using interrupted time...
Antibiotics are commonly prescribed for children with conditions which they provide no benefit, including viral respiratory infections. Broad-spectrum antibiotic use is increasing, adds unnecessary cost and promotes the development of resistance.To a nationally representative analysis prescribing in ambulatory pediatrics according to classes diagnostic categories identify factors associated broad-spectrum prescribing.We used National Ambulatory Hospital Medical Care surveys from 2006 2008,...
Objectives: To compare the prevalence, resource utilization, and mortality for pediatric severe sepsis identified using two established identification strategies. Design: Observational cohort study from 2004 to 2012. Setting: Forty-four hospitals contributing data Pediatric Health Information Systems database. Patients: Children 18 years old or younger. Measurements Main Results: We patients with septic shock by International Classification of Diseases, 9th edition, Clinical...
ABSTRACT Objectives: Variation in the prevalence of eosinophilic gastrointestinal diseases different geographical regions has not been extensively studied. The aim present study was to define regional and national diseases, differences practice approaches. Patients Methods: We administered a survey electronically members American College Gastroenterology, Academy Allergy, Asthma, Immunology, North Society Pediatric Hepatology, Nutrition. Questions pertained number proportion patients seen...
Abstract Evidenced-based guidelines for management of infants and children with community-acquired pneumonia (CAP) were prepared by an expert panel comprising clinicians investigators representing community pediatrics, public health, the pediatric specialties critical care, emergency medicine, hospital infectious diseases, pulmonology, surgery. These are intended use primary care subspecialty providers responsible otherwise healthy CAP in both outpatient inpatient settings. Site-of-care...
Variation in patient care or outcomes may indicate an opportunity to improve quality of care. We evaluated the variation testing, treatment, hospitalization rates, and febrile young infants US pediatric emergency departments (EDs).Retrospective cohort study <90 days age with a diagnosis code fever who were 1 37 EDs between July 1, 2011 June 30, 2013. assessed patient- hospital-level disposition for patients 3 distinct groups: ≤28, 29 56, 57 89 days. also compared interhospital 3-day revisits...
Postdischarge treatment of acute osteomyelitis in children requires weeks antibiotic therapy, which can be administered orally or intravenously via a peripherally inserted central catheter (PICC). The catheters carry risk for serious complications, but limited evidence exists on the effectiveness oral therapy.To compare and adverse outcomes postdischarge therapy PICC route.We performed retrospective cohort study comparing osteomyelitis. Among hospitalized from January 1, 2009, through...
Abstract This clinical practice guideline for the diagnosis and treatment of acute hematogenous osteomyelitis (AHO) in children was developed by a multidisciplinary panel representing Pediatric Infectious Diseases Society (PIDS) America (IDSA). is intended use healthcare professionals who care with AHO, including specialists pediatric infectious diseases, orthopedics, emergency physicians, hospitalists, any clinicians providers caring these patients. The panel’s recommendations AHO are based...
Vaccines have led to a significant decrease in rates of vaccine-preventable diseases and made impact on the health children. However, some parents express concerns about vaccine safety necessity vaccines. The range from hesitancy immunizations refusal all This clinical report provides information scope problem, facts surrounding common vaccination concerns, latest evidence regarding effective communication techniques for conversation. After reading this report, readers can expect to:...
To describe the magnitude of off-label drug use, to identify drugs most commonly used off-label, and factors associated with use in children hospitalized United States.Retrospective cohort study.Administrative database containing inpatient resource utilization data from January 1 December 31, 2004, 31 tertiary care pediatric hospitals States.Hospitalized patients 18 years or younger.Institution patient characteristics.Off-label was defined as a specific younger than Food Drug...
Occlusive vascular disease is a widespread abnormality leading to lethal or debilitating outcomes such as myocardial infarction and stroke. It part of atherosclerosis evoked by clinical procedures including angioplasty grafting saphenous vein in bypass surgery. A causative factor the switch smooth muscle cells an invasive proliferative mode, neointimal hyperplasia. Here we reveal importance this process TRPC1, homolog Drosophila transient receptor potential. Using 2 different vivo models...
To determine current rates of and trends in hospitalizations for community-acquired pneumonia (CAP) CAP-associated complications among children.We performed a cross-sectional, retrospective, cohort study by using the 1997, 2000, 2003, 2006 Kids' Inpatient Database. National estimates CAP local systemic complication were calculated children < or =18 years age. Patients with comorbid conditions in-hospital birth status excluded. Percentage changes 1997 (before heptavalent pneumococcal...
Children with complex chronic conditions depend on both their families and systems of pediatric health care, social services, financing. Investigations into the workings this ecology care would be advanced by more accurate methods population-level predictions likelihood for future hospitalization.This was a retrospective cohort study. Hospital administrative data were collected from 38 children's hospitals in United States years 2003-2005. Participants included patients between 2 18 age...
OBJECTIVE: Cerebrospinal fluid (CSF) white blood cell (WBC) counts for neonates and young infants are usually interpreted on the basis of values reported in reference texts or handbooks; however, current either present normal CSF parameters without citation cite studies with significant limitations. The objective this study was to determine accurate, age-specific WBC a large population infants. METHODS: This cross-sectional included patients who were aged ≤56 days had lumbar puncture...
<h3>Importance</h3> Medical errors and adverse events (AEs) are common among hospitalized children. While clinician reports the foundation of operational hospital safety surveillance a key component multifaceted research surveillance, patient family not routinely gathered. We hypothesized that novel family-reporting mechanism would improve incident detection. <h3>Objective</h3> To compare error AE rates (1) gathered systematically with vs without reporting, (2) reported by families...
Abstract BACKGROUND: Although chest radiography is commonly used to establish the diagnosis of pneumonia in children, reliability radiographic findings among radiologists not well described. OBJECTIVE: We sought evaluate inter‐rater and intra‐rater features described by childhood pneumonia. METHODS: Prospective case‐based study. One hundred ten radiographs children evaluated a pediatric emergency department for suspicion were interpreted six at two academic children's hospitals. Radiologists...
OBJECTIVE: To describe the variability across hospitals in diagnostic test utilization for children diagnosed with community-acquired pneumonia (CAP) during emergency department (ED) evaluation and to determine if is associated hospitalization ED revisits. METHODS: We conducted a retrospective cohort study of aged 2 months 18 years visits resulting CAP diagnoses from 2007 2010 who were seen at 36 contributing data Pediatric Health Information System. Children complex chronic conditions,...
Streptococcal toxic shock syndrome (TSS) is a rare and severe manifestation of group A streptococcal infection. The role intravenous immunoglobulin (IVIG) for TSS in children controversial. This study aims to describe the epidemiology determine whether adjunctive therapy with IVIG associated improved outcomes.A multicenter, retrospective cohort from 1 January 2003 through 31 December 2007 was conducted. Propensity scores were used each child's likelihood receiving IVIG. Differences primary...
Children undergoing congenital heart surgery often receive corticosteroids with the aim of reducing inflammatory response after cardiopulmonary bypass; however, value this approach is unclear.