A5068632203- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Drug-Induced Hepatotoxicity and Protection
- Organ Transplantation Techniques and Outcomes
- Alcohol Consumption and Health Effects
- Gallbladder and Bile Duct Disorders
- Diet, Metabolism, and Disease
- Pediatric Hepatobiliary Diseases and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Mechanisms and Therapy
- SARS-CoV-2 and COVID-19 Research
- Optimism, Hope, and Well-being
- Pancreatitis Pathology and Treatment
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Hepatitis C virus research
- Diet and metabolism studies
- Amoebic Infections and Treatments
- Pancreatic and Hepatic Oncology Research
- Genetic and Kidney Cyst Diseases
- Hemoglobinopathies and Related Disorders
- Research on Leishmaniasis Studies
- Colorectal Cancer Screening and Detection
- Parasites and Host Interactions
- Pesticide Exposure and Toxicity
Global Hospitals
2019-2025
Apollo Gleneagles Hospitals
2024
Institute of Liver and Biliary Sciences
2014-2021
All India Institute of Medical Sciences Rishikesh
2021
Sri Ramachandra Institute of Higher Education and Research
2019-2021
All India Institute of Medical Sciences
2014-2021
World Health Organization Regional Office for South-East Asia
2021
All India Institute of Medical Sciences Raipur
2021
Kasturba Medical College, Manipal
2020
Christian Medical College & Hospital
2014
Carvedilol is effective in the primary prophylaxis for large oesophageal varices. We investigated its use preventing progression of small to varices.Consecutive cirrhotics with varices were prospectively randomised either carvedilol (n=70) or placebo and followed up a minimum 24 months. Endoscopy was done at baseline six monthly intervals. Hepatic vein pressure gradient (HVPG) measured 12 The endpoint development varices.Baseline characteristics two groups comparable. predominant aetiology...
The choice of vasopressor for treating cirrhosis with septic shock is unclear. While noradrenaline in general the preferred vasopressor, terlipressin improves microcirculation addition to action non-cirrhotics. We compared efficacy and safety cirrhotics shock.Cirrhotics underwent open label randomization receive either (n=42) or infusion at a titrated dose. primary outcome was mean arterial pressure (MAP) >65 mm Hg 48 h.Baseline characteristics were comparable between groups.SBP pneumonia...
The presence of dermatologic reaction as an adverse event to sorafenib treatment in patients with unresectable hepatocellular carcinoma has been indicated a prognostic factor for survival recent prospective analysis. To date, this is the only clinical predictor response, which can be evaluated earlier and, therefore, contribute better and more individualized patient management.This retrospective study included 127 treated under real-life practice conditions two hepatology reference centers...
OBJECTIVES: Acute insults from viruses, infections, or alcohol are established causes of decompensation leading to acute-on-chronic liver failure (ACLF). Information regarding drugs as triggers ACLF is lacking. We examined data producing and analyzed clinical features, laboratory characteristics, outcome, predictors mortality in patients with drug-induced ACLF. METHODS: identified precipitants among prospective cohort the Asian Pacific Association Study Liver (APASL) Research Consortium...
Abstract Background and Aim There is limited data on predictors of acute kidney injury in chronic liver failure. We developed a PIRO model (Predisposition, Injury, Response, Organ failure) for predicting multicentric cohort failure patients. Patients Methods Data 2360 patients from APASL ‐ ACLF Research Consortium ( AARC ) was analysed. Multivariate logistic regression score) derivation (n=1363) which validated another prospective (n=997). Results Factors significant P component were serum...
Abstract Background Exogenous growth factor‐mobilized bone marrow ( BM ) stem cells have shown a differential response in the management of decompensated cirrhosis DC ). This study was designed to evaluate potential clinical benefit adding Erythropoietin EPO granulocyte‐colony stimulating factor (G‐ CSF )‐mobilized cell therapy, possible mechanisms regeneration and predictive factors regenerative response. Methods Sixty consecutive patients received either G‐ with (Group A; n = 30) or...
Abstract Background & Aims Familial aggregation of metabolic traits with fatty liver disease is well documented. However, there scarcity data regarding such association non‐alcoholic steatohepatitis ( NASH )‐related cirrhosis. This study was aimed to explore the family history severity Methods In a cross‐sectional study, all consecutive patients ‐related cirrhosis presenting our tertiary care centre were included. Family history, personal demographic characteristics, medical...
INTRODUCTION: The prevalence of metabolic dysfunction–associated fatty liver disease (MAFLD) and its complication, MAFLD-related acute-on-chronic failure (MAFLD-ACLF), is rising. Yet, factors determining patient outcomes in MAFLD-ACLF remain understudied. METHODS: Patients with were recruited from the Asian Pacific Association for Study Liver-ACLF Research Consortium (AARC registry). diagnosis was made when treating unit had identified etiology chronic as MAFLD (or previous nomenclature such...
Acute-on-chronic liver failure (ACLF) is characterized by acute decompensation of chronic disease associated with organ failures. Anemia diverse etiology common in patients ACLF. Spur cell anemia (SCA) a form acquired hemolytic that occurs rarely such due to dysregulated lipids metabolism. cells are large erythrocytes spike-like projections, which predispose them for sequestration and destruction splenic canaliculi. There paucity data on SCA Here we report series five ACLF who had severe...
Familial aggregation of metabolic traits in NAFLD is well documented. However, relevance these alcoholic cirrhosis not studied. We aimed to explore the association family history with age at diagnosis, severity and complications cirrhosis.In a cross-sectional study, all consecutive patients presenting our tertiary care centre were included. Family personal history, demographic characteristics, medical anthropometric measurements laboratory data recorded. The amount duration alcohol...