A5045640684- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Organ Transplantation Techniques and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Nutrition and Health in Aging
- Antifungal resistance and susceptibility
- Hepatitis Viruses Studies and Epidemiology
- Alcohol Consumption and Health Effects
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- Electrolyte and hormonal disorders
- COVID-19 Clinical Research Studies
- Frailty in Older Adults
- Clinical Nutrition and Gastroenterology
- HIV/AIDS drug development and treatment
- Diet, Metabolism, and Disease
- Nosocomial Infections in ICU
- Cystic Fibrosis Research Advances
- Artificial Intelligence in Healthcare
- Gastroesophageal reflux and treatments
- COVID-19 and healthcare impacts
- Liver physiology and pathology
- Diagnosis and treatment of tuberculosis
- Case Reports on Hematomas
Post Graduate Institute of Medical Education and Research
2016-2025
Public Works Department Buildings and Roads
2023
Amrita Institute of Medical Sciences and Research Centre
2023
Aster Medcity
2023
Chandigarh University
2019
New York Proton Center
2013
Abstract Aims To study the prevalence, risk factors, role of serum biomarkers for diagnosis and impact invasive fungal infections (IFIs) in patients with acute‐on‐chronic liver failure (ACLF). Methods An analysis IFI ACLF (EASL criteria) was conducted retrospectively. The clinically suspected based on EORTC/MSG criteria. demographical, clinical, laboratory details outcomes were analysed. Results Out 264 ACLF, 54 (20.4%) suspicion evaluated diagnosed 39 (14.7%). Invasive candidiasis...
Background & Aims: Treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI), with terlipressin and albumin, provides survival benefit, but may be associated cardiopulmonary complications. We analysed the predictors response mortality using point-of-care echocardiography (POC-Echo), cardiac renal biomarkers. Approach: Between December 2021 January 2023, patients HRS-AKI were assessed POC-Echo lung ultrasound within 6h admission, at time starting terlipressin(48h), 72h. Volume expansion...
Summary Background The precise estimation of cases with significant fibrosis (SF) is an unmet goal in non‐alcoholic fatty liver disease (NAFLD/MASLD). Aims We evaluated the performance machine learning (ML) and non‐patented scores for ruling out SF among NAFLD/MASLD patients. Methods Twenty‐one ML models were trained ( N = 1153), tested 283), validated 220) on clinical biochemical parameters histologically‐proven patients 1656) collected across 14 centres 8 Asian countries. Their detecting...
The relationship between ammonia and liver-related complications (LRCs) in acute-on-chronic liver failure (ACLF) patients is not clearly established. This study aimed to evaluate the association levels LRCs with ACLF. also evaluated ability of predicting mortality progression LRCs. prospectively recruited ACLF based on APASL definition from Research Consortium (AARC) 2009 2019. were a composite endpoint bacterial infection, overt hepatic encephalopathy (HE), ascites. A total 3871 cases...
Myokines are the muscle-derived hormones orchestrating muscle and systemic health. Their role in progression of alcohol-associated liver disease (ALD) remains elusive.
Decompensated cirrhosis (DC) carries a high mortality. Liver transplantation (LT) is the treatment of choice; however, limited availability donor organs has resulted in waitlist The present study investigated impact multiple courses granulocyte-colony stimulating factor (G-CSF) with or without growth hormone (GH) these patients. Sixty-five patients DC were randomized to standard medical therapy (SMT) plus G-CSF 3 monthly GH daily (group A; n = 23) SMT B; 21) alone C; 21). primary outcome was...
The reported burden of multidrug-resistant organism (MDRO) infections is highest in patients with cirrhosis from India. We evaluated whether colonisation at multiple barriers predisposes to such and poor outcomes cirrhosis.We prospectively performed swab cultures, antimicrobial susceptibility testing (AST), genotype for MDROs various sites (rectum, nose, composite-skin, central-line) (2020-2021) on admission follow-up a tertiary institute. analysed clinical data, risk factors MDROs, patient...
Abstract Background and Aim The majority of patients with decompensated cirrhosis suffer from malnutrition, a potentially modifiable contributor to frailty sarcopenia. present study investigated the impact 6‐month dietician‐supported home‐based intensive nutrition therapy (HINT) intervention on objective sarcopenia metrics in cirrhosis. Methods One hundred adult cirrhosis, frailty, at baseline were randomized 1:1 receive standard medical (SMT) plus HINT (intervention) versus SMT (control)...
Steatotic liver disease (SLD) is the most common cause of globally, with an ever-increasing burden. The two primary components SLD are metabolic dysfunction-associated steatotic (MASLD) and Alcohol-Associated Liver Disease (ALD). Both entities have important knowledge gaps in differentiation, diagnosis, risk stratification, prognosis. Given enormous burden both MASLD ALD their diverse presentation, they form ideal ground for application artificial intelligence (AI) machine learning (ML)...