Arka De

ORCID: 0000-0002-8567-1676
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Hepatitis C virus research
  • Nutrition and Health in Aging
  • Diet, Metabolism, and Disease
  • Organ Transplantation Techniques and Outcomes
  • Hepatitis B Virus Studies
  • Drug-Induced Hepatotoxicity and Protection
  • Alcohol Consumption and Health Effects
  • Hepatitis Viruses Studies and Epidemiology
  • Liver Diseases and Immunity
  • Clinical Nutrition and Gastroenterology
  • HIV/AIDS drug development and treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Diet and metabolism studies
  • Frailty in Older Adults
  • Gastroesophageal reflux and treatments
  • COVID-19 Clinical Research Studies
  • Diagnosis and treatment of tuberculosis
  • Gastrointestinal disorders and treatments
  • Folate and B Vitamins Research
  • Acute Kidney Injury Research
  • Electrolyte and hormonal disorders
  • Endoplasmic Reticulum Stress and Disease
  • Iron Metabolism and Disorders

Post Graduate Institute of Medical Education and Research
2016-2025

All India Institute of Medical Sciences Bhubaneswar
2024

Institute of Post Graduate Medical Education and Research
2024

Vellore Institute of Technology University
2023-2024

Chinese University of Hong Kong
2022

Leipzig University
2021

Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital
2016-2017

Bose Institute
2013

Kawasaki Hospital
2001

National Institute of Cholera and Enteric Diseases
2000

Background & Aims: Treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI), with terlipressin and albumin, provides survival benefit, but may be associated cardiopulmonary complications. We analysed the predictors response mortality using point-of-care echocardiography (POC-Echo), cardiac renal biomarkers. Approach: Between December 2021 January 2023, patients HRS-AKI were assessed POC-Echo lung ultrasound within 6h admission, at time starting terlipressin(48h), 72h. Volume expansion...

10.1097/hep.0000000000000691 article EN Hepatology 2023-11-16

Summary Background The precise estimation of cases with significant fibrosis (SF) is an unmet goal in non‐alcoholic fatty liver disease (NAFLD/MASLD). Aims We evaluated the performance machine learning (ML) and non‐patented scores for ruling out SF among NAFLD/MASLD patients. Methods Twenty‐one ML models were trained ( N = 1153), tested 283), validated 220) on clinical biochemical parameters histologically‐proven patients 1656) collected across 14 centres 8 Asian countries. Their detecting...

10.1111/apt.17891 article EN Alimentary Pharmacology & Therapeutics 2024-02-01

Myokines are the muscle-derived hormones orchestrating muscle and systemic health. Their role in progression of alcohol-associated liver disease (ALD) remains elusive.

10.1111/apt.18202 article EN Alimentary Pharmacology & Therapeutics 2024-08-12

Decompensated cirrhosis (DC) carries a high mortality. Liver transplantation (LT) is the treatment of choice; however, limited availability donor organs has resulted in waitlist The present study investigated impact multiple courses granulocyte-colony stimulating factor (G-CSF) with or without growth hormone (GH) these patients. Sixty-five patients DC were randomized to standard medical therapy (SMT) plus G-CSF 3 monthly GH daily (group A; n = 23) SMT B; 21) alone C; 21). primary outcome was...

10.1002/hep.29763 article EN Hepatology 2017-12-26

The reported burden of multidrug-resistant organism (MDRO) infections is highest in patients with cirrhosis from India. We evaluated whether colonisation at multiple barriers predisposes to such and poor outcomes cirrhosis.We prospectively performed swab cultures, antimicrobial susceptibility testing (AST), genotype for MDROs various sites (rectum, nose, composite-skin, central-line) (2020-2021) on admission follow-up a tertiary institute. analysed clinical data, risk factors MDROs, patient...

10.1016/j.jhepr.2023.100788 article EN cc-by JHEP Reports 2023-05-11

Abstract Background and Aim The majority of patients with decompensated cirrhosis suffer from malnutrition, a potentially modifiable contributor to frailty sarcopenia. present study investigated the impact 6‐month dietician‐supported home‐based intensive nutrition therapy (HINT) intervention on objective sarcopenia metrics in cirrhosis. Methods One hundred adult cirrhosis, frailty, at baseline were randomized 1:1 receive standard medical (SMT) plus HINT (intervention) versus SMT (control)...

10.1111/jgh.16035 article EN Journal of Gastroenterology and Hepatology 2022-10-21
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