- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Hepatitis C virus research
- Organ Transplantation Techniques and Outcomes
- Nutrition and Health in Aging
- Hepatitis Viruses Studies and Epidemiology
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- Liver Diseases and Immunity
- COVID-19 Clinical Research Studies
- Clinical Nutrition and Gastroenterology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Alcohol Consumption and Health Effects
- Pediatric Hepatobiliary Diseases and Treatments
- Folate and B Vitamins Research
- SARS-CoV-2 and COVID-19 Research
- Sexual function and dysfunction studies
- Gallbladder and Bile Duct Disorders
- HIV/AIDS drug development and treatment
- Frailty in Older Adults
- Antifungal resistance and susceptibility
- Diet and metabolism studies
- Hemodynamic Monitoring and Therapy
- Pharmacological Effects and Toxicity Studies
Post Graduate Institute of Medical Education and Research
2016-2025
Institute of Post Graduate Medical Education and Research
2024
All India Institute of Medical Sciences Bhubaneswar
2024
Yashoda Hospital
2017-2023
Institute of Liver and Biliary Sciences
2021
Vancouver General Hospital
2019-2020
Mahatma Gandhi Institute of Medical Sciences
2020
St. Johns Hospital
2020
All India Institute of Medical Sciences Rishikesh
2020
University of British Columbia
2020
More than a billion Indians currently stand at the precipice of massive increase in cases coronavirus disease 2019 (COVID-19). India had shown staggered course severe acute respiratory syndrome 2 (SARS-CoV-2) transmission, with 1397 diagnosed between Jan 31, and April 1, 2020. However, there has been recent surge cases, numbers rising to 5194 as 8.1Our World DataTotal daily confirmed COVID-19 India.https://ourworldindata.org/grapher/total-and-daily-cases-covid-19?country=INDDate: 2020Date...
India's current COVID-19 surge is an unprecedented public health crisis.With exponential growth in the number of daily cases since March, 2021, India reported more than 400 000 new on May 1, 2021. 1 This likely to be underestimate true burden cases, given reports backlogs test results, poor access testing, and many people not getting tested due fear stigma. 2,3Without mitigation, estimates suggest could reach million per day with over cumulative deaths by Aug 4 The Indian Government...
ABSTRACT Background and Aims We assessed clinical, procoagulant genetic risk factors clinical outcomes in dabigatran‐treated patients with non‐tumoural acute acute‐on‐chronic portal vein thrombosis (PVT). Methods Patients a new diagnosis of PVT between January 2021 2024 (aged ≥ 18 years) those without/with cirrhosis (Child‐Pugh (CP)‐A/B/C ≤ 10) were started on dabigatran followed compared vitamin K antagonist (VKA) untreated individuals. Results Dabigatran was prescribed 119 type 1 (61,...
Background & Aims: Treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI), with terlipressin and albumin, provides survival benefit, but may be associated cardiopulmonary complications. We analysed the predictors response mortality using point-of-care echocardiography (POC-Echo), cardiac renal biomarkers. Approach: Between December 2021 January 2023, patients HRS-AKI were assessed POC-Echo lung ultrasound within 6h admission, at time starting terlipressin(48h), 72h. Volume expansion...
Myokines are the muscle-derived hormones orchestrating muscle and systemic health. Their role in progression of alcohol-associated liver disease (ALD) remains elusive.
The reported burden of multidrug-resistant organism (MDRO) infections is highest in patients with cirrhosis from India. We evaluated whether colonisation at multiple barriers predisposes to such and poor outcomes cirrhosis.We prospectively performed swab cultures, antimicrobial susceptibility testing (AST), genotype for MDROs various sites (rectum, nose, composite-skin, central-line) (2020-2021) on admission follow-up a tertiary institute. analysed clinical data, risk factors MDROs, patient...
Patients with cirrhosis are susceptible to decompensation events, including ascites, variceal bleeding (VB), hepatic encephalopathy, or death after COVID-19 infection. may experience post-COVID condition (PCC) multisystem involvement that persists for at least 2 months. Hospitalized patients and between January 2021 2023 were assessed events mortality compared a propensity-matched cohort of non-COVID-19 sepsis. Both groups followed outcomes over 1 year. Of 252 Cirrhosis+ (73% men, aged 48.9...
Occlusion of spontaneous portosystemic shunts (SPSSs) in patients with cirrhosis may be required recurrent or refractory hepatic encephalopathy. We describe a novel method for occlusion SPSS using endoscopic ultrasound (EUS).EUS-guided transgastric shunt obliteration was performed by injecting glue and coils directly into SPSS.EUS-guided 7 9 sessions. Complete cessation Doppler flow achieved 6/7 cases. Adequate clinical response observed patients. No procedure-related severe adverse events...
Summary Background Point‐of‐care echocardiography (POC‐Echo) is an essential intensive care hemodynamic monitoring tool. Aims To assess POC‐Echo parameters [ i.e ., cardiac index (CI), systemic vascular resistance (SVRI) and cirrhotic cardiomyopathy (CCM) markers] serum biomarkers in predicting circulatory failure (need for vasopressors) mortality patients with acute‐on‐chronic liver (ACLF) having sepsis‐induced hypotension. Methods We performed serial within 6 hours (h) of presentation...
Machine learning (ML) can identify the hidden patterns without hypothesis in heterogeneous diseases like acute-on-chronic live failure (ACLF). We employed ML to describe and predict yet unknown clusters ACLF.
Acetaminophen is one of the most commonly consumed analgesics world wide. Generally perceived as a safe medication, it common cause acute liver failure in United States with inadvertent hepatotoxicity half all cases. We therefore conducted survey on public perceptions acetaminophen patients attending outpatient clinic Vancouver, Canada. Among 928 who were asked, 765 completed questionnaire. The majority respondents female (59%), Caucasian (61%), and educated beyond secondary school level...