Sahaj Rathi

ORCID: 0000-0001-6529-9080
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About
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Research Areas
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Drug-Induced Hepatotoxicity and Protection
  • Hepatitis C virus research
  • Organ Transplantation Techniques and Outcomes
  • Nutrition and Health in Aging
  • Hepatitis Viruses Studies and Epidemiology
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Hepatitis B Virus Studies
  • Liver Diseases and Immunity
  • COVID-19 Clinical Research Studies
  • Clinical Nutrition and Gastroenterology
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Alcohol Consumption and Health Effects
  • Pediatric Hepatobiliary Diseases and Treatments
  • Folate and B Vitamins Research
  • SARS-CoV-2 and COVID-19 Research
  • Sexual function and dysfunction studies
  • Gallbladder and Bile Duct Disorders
  • HIV/AIDS drug development and treatment
  • Frailty in Older Adults
  • Antifungal resistance and susceptibility
  • Diet and metabolism studies
  • Hemodynamic Monitoring and Therapy
  • Pharmacological Effects and Toxicity Studies

Post Graduate Institute of Medical Education and Research
2016-2025

Institute of Post Graduate Medical Education and Research
2024

All India Institute of Medical Sciences Bhubaneswar
2024

Yashoda Hospital
2017-2023

Institute of Liver and Biliary Sciences
2021

Vancouver General Hospital
2019-2020

Mahatma Gandhi Institute of Medical Sciences
2020

St. Johns Hospital
2020

All India Institute of Medical Sciences Rishikesh
2020

University of British Columbia
2020

More than a billion Indians currently stand at the precipice of massive increase in cases coronavirus disease 2019 (COVID-19). India had shown staggered course severe acute respiratory syndrome 2 (SARS-CoV-2) transmission, with 1397 diagnosed between Jan 31, and April 1, 2020. However, there has been recent surge cases, numbers rising to 5194 as 8.1Our World DataTotal daily confirmed COVID-19 India.https://ourworldindata.org/grapher/total-and-daily-cases-covid-19?country=INDDate: 2020Date...

10.1016/s1473-3099(20)30313-3 article EN other-oa The Lancet Infectious Diseases 2020-04-17

India's current COVID-19 surge is an unprecedented public health crisis.With exponential growth in the number of daily cases since March, 2021, India reported more than 400 000 new on May 1, 2021. 1 This likely to be underestimate true burden cases, given reports backlogs test results, poor access testing, and many people not getting tested due fear stigma. 2,3Without mitigation, estimates suggest could reach million per day with over cumulative deaths by Aug 4 The Indian Government...

10.1016/s0140-6736(21)01121-1 article EN other-oa The Lancet 2021-05-14

ABSTRACT Background and Aims We assessed clinical, procoagulant genetic risk factors clinical outcomes in dabigatran‐treated patients with non‐tumoural acute acute‐on‐chronic portal vein thrombosis (PVT). Methods Patients a new diagnosis of PVT between January 2021 2024 (aged ≥ 18 years) those without/with cirrhosis (Child‐Pugh (CP)‐A/B/C ≤ 10) were started on dabigatran followed compared vitamin K antagonist (VKA) untreated individuals. Results Dabigatran was prescribed 119 type 1 (61,...

10.1111/apt.18474 article EN Alimentary Pharmacology & Therapeutics 2025-01-03

Background & Aims: Treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI), with terlipressin and albumin, provides survival benefit, but may be associated cardiopulmonary complications. We analysed the predictors response mortality using point-of-care echocardiography (POC-Echo), cardiac renal biomarkers. Approach: Between December 2021 January 2023, patients HRS-AKI were assessed POC-Echo lung ultrasound within 6h admission, at time starting terlipressin(48h), 72h. Volume expansion...

10.1097/hep.0000000000000691 article EN Hepatology 2023-11-16

Myokines are the muscle-derived hormones orchestrating muscle and systemic health. Their role in progression of alcohol-associated liver disease (ALD) remains elusive.

10.1111/apt.18202 article EN Alimentary Pharmacology & Therapeutics 2024-08-12

The reported burden of multidrug-resistant organism (MDRO) infections is highest in patients with cirrhosis from India. We evaluated whether colonisation at multiple barriers predisposes to such and poor outcomes cirrhosis.We prospectively performed swab cultures, antimicrobial susceptibility testing (AST), genotype for MDROs various sites (rectum, nose, composite-skin, central-line) (2020-2021) on admission follow-up a tertiary institute. analysed clinical data, risk factors MDROs, patient...

10.1016/j.jhepr.2023.100788 article EN cc-by JHEP Reports 2023-05-11

Patients with cirrhosis are susceptible to decompensation events, including ascites, variceal bleeding (VB), hepatic encephalopathy, or death after COVID-19 infection. may experience post-COVID condition (PCC) multisystem involvement that persists for at least 2 months. Hospitalized patients and between January 2021 2023 were assessed events mortality compared a propensity-matched cohort of non-COVID-19 sepsis. Both groups followed outcomes over 1 year. Of 252 Cirrhosis+ (73% men, aged 48.9...

10.1002/jgh3.70142 article EN cc-by-nc JGH Open 2025-03-01

Occlusion of spontaneous portosystemic shunts (SPSSs) in patients with cirrhosis may be required recurrent or refractory hepatic encephalopathy. We describe a novel method for occlusion SPSS using endoscopic ultrasound (EUS).EUS-guided transgastric shunt obliteration was performed by injecting glue and coils directly into SPSS.EUS-guided 7 9 sessions. Complete cessation Doppler flow achieved 6/7 cases. Adequate clinical response observed patients. No procedure-related severe adverse events...

10.14309/ajg.0000000000002477 article EN The American Journal of Gastroenterology 2023-08-17

Summary Background Point‐of‐care echocardiography (POC‐Echo) is an essential intensive care hemodynamic monitoring tool. Aims To assess POC‐Echo parameters [ i.e ., cardiac index (CI), systemic vascular resistance (SVRI) and cirrhotic cardiomyopathy (CCM) markers] serum biomarkers in predicting circulatory failure (need for vasopressors) mortality patients with acute‐on‐chronic liver (ACLF) having sepsis‐induced hypotension. Methods We performed serial within 6 hours (h) of presentation...

10.1111/apt.17695 article EN Alimentary Pharmacology & Therapeutics 2023-09-09

Machine learning (ML) can identify the hidden patterns without hypothesis in heterogeneous diseases like acute-on-chronic live failure (ACLF). We employed ML to describe and predict yet unknown clusters ACLF.

10.1111/apt.18274 article EN Alimentary Pharmacology & Therapeutics 2024-09-23

Acetaminophen is one of the most commonly consumed analgesics world wide. Generally perceived as a safe medication, it common cause acute liver failure in United States with inadvertent hepatotoxicity half all cases. We therefore conducted survey on public perceptions acetaminophen patients attending outpatient clinic Vancouver, Canada. Among 928 who were asked, 765 completed questionnaire. The majority respondents female (59%), Caucasian (61%), and educated beyond secondary school level...

10.1371/journal.pone.0229070 article EN cc-by PLoS ONE 2020-03-04
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