Philip Abraham

ORCID: 0000-0002-0604-3306
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About
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Research Areas
  • Inflammatory Bowel Disease
  • Liver Disease and Transplantation
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal motility and disorders
  • Microscopic Colitis
  • Liver Disease Diagnosis and Treatment
  • Diagnosis and treatment of tuberculosis
  • Gastroesophageal reflux and treatments
  • Eosinophilic Esophagitis
  • Clinical Nutrition and Gastroenterology
  • Tuberculosis Research and Epidemiology
  • Organ Transplantation Techniques and Outcomes
  • Pancreatitis Pathology and Treatment
  • Esophageal and GI Pathology
  • Neurotransmitter Receptor Influence on Behavior
  • Gallbladder and Bile Duct Disorders
  • Colorectal Cancer Screening and Detection
  • Abdominal vascular conditions and treatments
  • Pediatric Hepatobiliary Diseases and Treatments
  • Diverticular Disease and Complications
  • Nutrition and Health in Aging
  • Therapeutic Uses of Natural Elements
  • Crystallization and Solubility Studies
  • Gastrointestinal disorders and treatments
  • Congenital gastrointestinal and neural anomalies

P. D. Hinduja Hospital and Medical Research Centre
2016-2025

National Hospital
2005-2024

National Institute of Diabetes and Digestive and Kidney Diseases
2020

ProQuest (United States)
2020

Hudson Institute
2020

Post Graduate Institute of Medical Education and Research
2013-2017

Fortis Hospital
2017

Sir Ganga Ram Hospital
2017

Yashoda Hospital
2017

Fortis Memorial Research Institute
2017

Abstract To explore the natural microbial community of any ecosystems by high-resolution molecular approaches including next generation sequencing, it is extremely important to develop a sensitive and reproducible DNA extraction method that facilitate isolation sufficient purity quantity from culturable uncultured species living in environment. Proper lysis heterogeneous cells without damaging their genomes major challenge. In this study, we have developed an improved for different...

10.1038/srep26775 article EN cc-by Scientific Reports 2016-05-31

Campylobacter pylori has been implicated as a causative factor in acid-peptic disease. Lactobacillus acidophilus is known to inhibit the growth of pathogens human gastrointestinal tract. We recovered C. from gastric antral biopsies seven patients with disease; isolates were then cultured brucella broth. The effect L. (cultured DeMan-Rogosa-Sharpe broth) on was tested by mixed culture technique. inhibited all vitro. All these also supernatant (brucella blood agar cup technique) obtained at or...

10.1128/jcm.27.10.2328-2330.1989 article EN Journal of Clinical Microbiology 1989-10-01

Chronic constipation (CC) may impact on quality of life. There is substantial patient dissatisfaction; possible reasons are failure to recognize underlying constipation, inappropriate dietary advice and inadequate treatment. The aim these practical guidelines intended for primary care physicians, which based Asian perspectives, provide an approach CC that relevant the existing health-care infrastructure. Physicians should not rely infrequent bowel movements diagnose as many patients have one...

10.5056/jnm.2013.19.2.149 article EN cc-by-nc Journal of Neurogastroenterology and Motility 2013-04-26

Background/AimsSarcopenia is implicated in inflammatory bowel disease (IBD) complications and surgical outcomes. This study aimed to investigate the prevalence follow-up of sarcopenia patients with IBD. MethodsConsecutive consenting IBD aged > 18 years were included. Patients associated sarcopenic diseases excluded. All had measurements anthropometry, body mass index (BMI), mid-arm muscle circumference, strength, physical performance, (on computed tomography scan). They followed up for 12...

10.5217/ir.2024.00096 article EN cc-by-nc Intestinal Research 2025-01-23

The gastric microbiome is suspected to have a role in the causation of diseases by Helicobacter pylori. Reports on their relative abundance vis-à-vis H. pylori are available from various ethnic and geographic groups, but little known about interaction patterns. Endoscopic mucosal biopsy samples antrum corpus 39 patients with infection were collected microbiomes analyzed 16S rDNA profiling. Four groups identified, which harbored as well diverse group bacteria including Lactobacillus,...

10.1038/s41598-017-15510-6 article EN cc-by Scientific Reports 2017-11-07

The Indian Motility and Functional Diseases Association the Society of Gastroenterology developed this evidence-based practice guideline for management chronic constipation. A modified Delphi process was used to develop consensus containing 29 statements, which were generated by electronic voting iteration as well face meeting review supporting literature primarily from India. These statements include 9 on epidemiology, clinical presentation, diagnostic criteria; 8 pathophysiology; remaining...

10.1007/s12664-018-0894-1 article EN cc-by Indian Journal of Gastroenterology 2018-11-01

Abstract Introduction These Asian Working Group guidelines on diet in inflammatory bowel disease (IBD) present a multidisciplinary focus clinical nutrition IBD countries. Methodology The are based evidence from existing published literature; however, if objective data were lacking or inconclusive, expert opinion was considered. conclusions and 38 recommendations have been subject to full peer review Delphi process which uniformly positive responses (agree strongly agree) required. Results...

10.1007/s12664-019-00976-1 article EN cc-by Indian Journal of Gastroenterology 2019-06-01

The Indian Neurogastroenterology and Motility Association (INMA), earlier named the Functional Diseases developed this evidence-based practice guidelines for management of irritable bowel syndrome (IBS). A modified Delphi process was used to develop consensus containing 28 statements, which were concerning diagnostic criteria, epidemiology, etiopathogenesis comorbidities, investigations, lifestyle modifications treatments. Owing Coronavirus disease-19 (COVID-19) pandemic, lockdowns mobility...

10.1007/s12664-022-01333-5 article EN cc-by Indian Journal of Gastroenterology 2023-03-24

Abstract Background Physician and patient acceptance of the T2T approach is not universal.1,2 We prospectively studied (a) proportion patients with IBD achieving response (STRIDE II consensus); (b) patient-, disease- physician-related factors affecting feasibility approach. Methods Patients were followed up for clinical, biomarker, endoscopic, radiologic histologic response, as defined in revised guidelines.3 In whom it was achieved, possible responsible studied. Results 160 enrolled –...

10.1093/ecco-jcc/jjae190.0772 article EN Journal of Crohn s and Colitis 2025-01-01

Twenty six patients with portal hypertension of different aetiologies were studied for endoscopic evidence congestive gastroduodenopathy and histological gastropathy jejunopathy. Per oral biopsies jejunum taken by Watson9s capsule. Normal biopsy tissues obtained from the antrum (26), fundus (10), (26) used as controls. Endoscopy showed changes in (17 cases), (17), duodenum (4). Duodenopathy correlated but not fundus. Histology an increase size number vessels jejunal villi (9congestive...

10.1136/gut.34.5.694 article EN Gut 1993-05-01

Abstract [ 123 I]RTI‐55, an iodinated derivative of the cocaine analog 3β‐phenyltropane‐2β‐carboxylic acid methyl ester, was evaluated as agent for in vivo labeling serotonin transporter. Labeling precursor RTI‐55 with I‐123 efficient and yielded a high specific activity product. After intravenous injection I]RTI‐55 into rats, tracer accumulated regions densities dopamine uptake sites. The distribution binding areas rich sites correlated 3 H]serotonin measured vitro same regions. Specific to...

10.1002/syn.890110206 article EN Synapse 1992-06-01
Séverine Vermeire Péter L. Lakatos Timothy E. Ritter Stephen B. Hanauer Brian Bressler and 95 more Reena Khanna Kim L. Isaacs Saumin Shah Alysha Kadva Helen E.J. Tyrrell Young S. Oh Swati Tole Akiko Chai Jennifer Pulley Christopher Eden Wenhui Zhang Brian G. Feagan Philip Abraham Mauro Acir Crippa Júnior Humberto Aguilar Tasneem Ahmed I Altorjay Vibeke Andersen Ronen Arai Hays Arnold Karlee Ausk Jeffrey Axler Kamran Ayub Avinash Balekuduru Guerino Barbalaco Neto Isaac Bassan Brian W. Behm Pradeep Bekal Shobna Bhatia Barnabás Bod Carlos Eduardo Brandão‐Mello Julia Brandeburova Johannes Breedt Brian Bressler Ivan V. Chopey Michael Connor Richard Corlin Carlos Alejandro Cortez Hernandez Arijit De Alexander de Sá Rolim Sandra Di Felice Boratto Tyler Dixon D. Poli D Dresner George Aaron Du Vall Matthias Ebert Robert Ehehalt Atilla Ertan R Valencia Jason Etzel Jan Fallingborg Brian G. Feagan Miroslav Fedurco Enrique Castro Valéria Ferreira de Almeida e Borges Mark Finklestein Andreas Fischer Mark R. Fleisher Angel Ricardo Flores Rendon Ronald Fogel Osvaldo Franceschi Curtis Freedland David Gatof Kanwar R. Gill Henning Glerup Vardaraj Gokak Eran Goldin Hector Alejandro Gomez Jaramillo Nitin Gupta Z Gurzó Olga Gyrina Mohammed Aejaz Habeeb Stephen Hanauer Robert Hardi William R. Harlan Ammar Hemaidan Melvin Heyman Péter Hoffmann William Holderman Frank Holtkamp-Endemann Gyula Horvat Kim L. Isaacs Eran Israeli Sender Jankiel Miszputen Søren Kejser Jensen Kenneth P. Johnson Jennifer Jones Osvaldo Da Silva Júnior Barbora Kadleckova Mukesh Kalla Zsuzsanna Kallo N C Karyotakis Lior H. Katz Leo Katz Nirmal Kaur

10.1016/s2468-1253(21)00295-8 article EN ˜The œLancet. Gastroenterology & hepatology 2021-11-17

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTN-Modified analogs of cocaine: synthesis and inhibition binding to the cocaine receptorPhilip Abraham, J. Bruce Pitner, Anita H. Lewin, John W. Boja, Michael Kuhar, F. Ivy CarrollCite this: Med. Chem. 1992, 35, 1, 141–144Publication Date (Print):January 1992Publication History Published online1 May 2002Published inissue 1 January 1992https://pubs.acs.org/doi/10.1021/jm00079a018https://doi.org/10.1021/jm00079a018research-articleACS...

10.1021/jm00079a018 article EN Journal of Medicinal Chemistry 1992-01-01
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