Valéria Ferreira de Almeida e Borges
A5082675199- Liver Diseases and Immunity
- Liver Disease Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Liver Disease and Transplantation
- Inflammatory Bowel Disease
- Diet, Metabolism, and Disease
- Microscopic Colitis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Systemic Lupus Erythematosus Research
- Biliary and Gastrointestinal Fistulas
- Hepatitis C virus research
- Lipid metabolism and disorders
- Eosinophilic Esophagitis
- Tracheal and airway disorders
- Drug Transport and Resistance Mechanisms
- Dysphagia Assessment and Management
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Helicobacter pylori-related gastroenterology studies
- Alkaline Phosphatase Research Studies
Universidade Federal de Uberlândia
2000-2025
Universidade Federal da Bahia
2024
Universidade Federal de Minas Gerais
2024
Instituto de Gastroenterología
2024
Abstract Purpose. To evaluate the accuracy of sonographic hepatorenal ratio (HRR) in diagnosis and grading nonalcoholic steatosis, using biopsy as reference. Methods. Ultrasound (US) liver were performed 42 patients with fatty disease. Forty healthy volunteers without steatosis at US risk factors for disease also studied. The HRR was obtained by dividing mean brightness level region‐of‐interest pixels hepatic parenchyma that renal parenchyma. Needle samples (hematoxylin‐eosin stained)...
Abstract Background Biological therapy has revolutionized the treatment of inflammatory bowel disease (IBD); however, a subset patients still requires optimization to achieve therapeutic goals. This study aimed identify who underwent biological (TO) and compare their characteristics with those did not require such adjustments. Methods A retrospective was conducted using data from national patient registry GEDIIB (Brazilian Crohn's Colitis Organization). total 1,660 (CD) 530 ulcerative...
Aim: Up to 40% of patients with primary biliary cholangitis (PBC) will have a suboptimal biochemical response ursodeoxycholic acid (UDCA), which can be improved by the addition fibrates. This exploratory study aims evaluate long-term real-life different fibrates, including ciprofibrate, in subjects UDCA-unresponsive PBC. Methods: The Brazilian Cholestasis Study Group multicenter database was reviewed assess rates UDCA plus fibrates PBC 1 and 2 years after treatment initiation validated...
Background Ursodeoxycholic acid (UDCA) is the standard treatment for primary biliary cholangitis (PBC), but a significant proportion of patients do not respond adequately, leading to increased risk adverse outcomes. This study aims develop new and straightforward predictive score identify PBC likely achieve complete response UDCA. Methods A logistic regression analysis was conducted using derivation cohort pre-treatment variables associated with led development ALP-A score, calculated as:...
ABSTRACT Background and Aim Primary sclerosing cholangitis (PSC) has been shown to recur after liver transplantation (LT). Some studies have identified certain clinical laboratory variables associated with an increased risk for recurrent PSC (rPSC) in Caucasians. Furthermore, de novo cholangiocarcinoma (CCA) reported anecdotally patients rPSC. This study aims assess the prevalence of rPSC, identify its factors, investigate occurrence CCA a highly admixed population from Brazil. Methods All...
Little is known about primary biliary cholangitis (PBC) in non-whites. The purpose of this study was to evaluate clinical features and outcomes PBC a highly admixed population. Brazilian Cholestasis Study Group multicentre database reviewed assess demographics, treatment patients with PBC. 562 (95% females, mean age 51 ± 11 years) were included. Concurrent autoimmune diseases overlap hepatitis (AIH) occurred, respectively, 18.9% 14%. After follow-up 6.2 5.3 years, 32% had cirrhosis, 7%...
CONTEXT: Hepatitis C is an important cause of chronic liver disease worldwide. The grading hepatic fibrosis in hepatitis for better clinical management. However, until now, biopsy the only test accepted this purpose, despite their contraindications and complications. New methods non-invasive assessment are under investigation. One proposal Doppler ultrasound, as a non-invasive, widely available inexpensive. OBJECTIVE: To compare parameters portal vein patients with healthy control group to...
OBJETIVO: Avaliar a correlação entre dopplerfluxometria da veia hepática direita e o grau de esteatose, inflamação fibrose à biópsia na doença gordurosa não alcoólica. MATERIAIS E MÉTODOS: Foi realizada ultrassonografia com Doppler em 80 pacientes, sendo 40 portadores alcoólica, também submetidos biópsia. Quarenta controles normais saudáveis, sem fatores risco para alcoólica foram Doppler. O padrão ao foi classificado trifásico, bifásico monofásico. Os espécimes classificados conforme...
Primary sclerosing cholangitis (PSC) is associated with a broad phenotypic spectrum in different populations from diverse ethnic and racial backgrounds. This study aimed to describe the clinical characteristics outcomes of PSC multicenter cohort patients Brazil.Data Brazilian Cholestasis Study Group were retrospectively reviewed assess demographic information PSC, as well outcomes, such transplantation-free survival.This included 210 patients. After excluding 33 (15.7%) overlap syndrome...
Primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH) PBC overlap syndrome (AIH/PBC) have been associated with a higher risk of hepatocellular carcinoma (HCC) extra-hepatic malignancy (EHM). This study aims to assess potential factors cancer development in AIH/PBC.The Brazilian Cholestasis Study Group database was reviewed compare clinical laboratory features patients HCC EHM those without cancer.Among the 752 enrolled, 64 them AIH/PBC, 87 cancers were identified 72 patients,...
Abstract Background: Cholangiopathy has been described in survivors of severe COVID-19, presenting significant clinical parallels to the pre-pandemic condition secondary sclerosing cholangitis critically ill patients (SSC-CIP). Aim: Herein, we examined liver histopathology individuals with persistent cholestasis following COVID-19. Methods: Post-COVID-19 samples were subjected routine staining techniques and cytokeratin 7 immunostaining, portal parenchymal changes semi-quantitatively...
Cholangiopathy has been described in survivors of severe COVID-19, presenting significant clinical parallels to the pre-pandemic condition secondary sclerosing cholangitis critically ill patients (SSC-CIP). We aimed examine liver histopathology individuals with persistent cholestasis after COVID-19.
Little is known about primary biliary cholangitis (PBC) in Latin America, where this disease thought to be rare. To analyze clinical and biochemical features of Brazilian PBC patients. The Cholestasis Study Group multicentre database was reviewed assess demographics, laboratory from 562 patients with were included; 80 (14.2%) had overlapping syndrome autoimmune hepatitis excluded. Most subjects middle-aged women (95%; mean age 51 ± 11 years) classical symptoms pruritus and/or fatigue (65%)...