A5078686319- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Women's cancer prevention and management
- Biosimilars and Bioanalytical Methods
- Healthcare Systems and Reforms
- Liver Diseases and Immunity
- Pregnancy and Medication Impact
- Diverticular Disease and Complications
- Mineral Processing and Grinding
- Pancreatic and Hepatic Oncology Research
- Nutrition and Health in Aging
- Colorectal and Anal Carcinomas
- Hedgehog Signaling Pathway Studies
- Biliary and Gastrointestinal Fistulas
- Tuberculosis Research and Epidemiology
- Nonmelanoma Skin Cancer Studies
- Autoimmune and Inflammatory Disorders
- Spectroscopy Techniques in Biomedical and Chemical Research
- Healthcare cost, quality, practices
- Stoma care and complications
- Public Health in Brazil
- COVID-19 and healthcare impacts
- Colorectal Cancer Screening and Detection
- Science and Education Research
Hospital Ortopédico de Passo Fundo
2020-2025
Hospital de Clínicas
2023-2025
Hospital São Vicente
2019-2024
Hospital São Paulo
2024
Takeda (United States)
2023
Pfizer (United States)
2023
Janssen (Belgium)
2023
Pfizer (United Kingdom)
2023
Universidade Estadual Paulista (Unesp)
2023
Hospital Universitário de Santa Maria
2023
Abstract Background Biological therapy has revolutionized the treatment of inflammatory bowel disease (IBD); however, a subset patients still requires optimization to achieve therapeutic goals. This study aimed identify who underwent biological (TO) and compare their characteristics with those did not require such adjustments. Methods A retrospective was conducted using data from national patient registry GEDIIB (Brazilian Crohn's Colitis Organization). total 1,660 (CD) 530 ulcerative...
Abstract Background This study aimed to evaluate the real-world, long-term effectiveness and safety of tofacitinib in a large cohort patients with refractory or difficult-to-treat ulcerative colitis (UC). Methods A multicentre, retrospective, observational was conducted, including moderately severely active UC who received for at least 8 weeks. Outcomes assessed included clinical remission response, endoscopic response remission, biochemical steroid-free primary secondary loss drug...
To assess the real-life, long-term effectiveness and safety of tofacitinib in a large cohort patients with refractory or difficult-to-treat ulcerative colitis (UC). This multicenter, retrospective, observational study included moderately to severely active UC who received for at least 8 weeks. Clinical remission response, endoscopic response remission, biochemical steroid-free clinical primary secondary loss drug discontinuation, need dose optimization, colectomy, adverse events were...
Malnourished patients with gastrointestinal tumours are at risk for postoperative complications and death. The aim of this study was to determine which nutritional assessment method better predicts outcome. Seventy-four patients, 45 men 29 women; mean (SD) age 63 (102) yr (range = 34 83), undergoing surgical resections esophageal (n 19) gastric 43) pancreatic 12) tumors were preoperatively assessed by Patient Generated Subjective Global Assessment, anthropometry, laboratory sampling....
Abstract Background Real-world data on the effectiveness and safety of ustekinumab (UST) in ulcerative colitis (UC) are lacking Latin America. In this study, we aimed to describe UST a real-world multicenter cohort Brazilian patients with UC. Methods We conducted retrospective observational including moderate-to-severe UC (total Mayo score 6–12, an endoscopic subscore 2 or 3) who received UST. The co-primary endpoints were clinical remission, defined as total ≤2 at 1 year, combined rectal...
Approximately 25% of patients with inflammatory bowel disease (IBD) develop the during childhood or adolescence and treatment aims to control active symptoms prevent long-term complications. The management Crohn's (CD) ulcerative colitis (UC) can be especially challenging in children adolescents, related particularities that may affect growth, development, puberty.This consensus provide guidance on most effective medical surgical pediatric CD UC.Experts Pediatric IBD representing Brazilian...
ABSTRACT BACKGROUND: Inflammatory bowel diseases (IBD) are chronic inflammatory affections of recurrent nature whose incidence and prevalence rates have increased, including in Brazil. In long term, they responsible for structural damage that impacts quality life, morbidity mortality patients. OBJECTIVE: To describe the profile physicians who treat IBD patients as well characteristics care, unmet demands difficulties. METHODS: A questionnaire containing 17 items was prepared sent to 286 from...
Background: Despite optimized medical therapy, contemporary risk of surgery in inflammatory bowel diseases (IBD) after 10 years diagnosis is 9.2% patients with ulcerative colitis (UC) and 26.2% Crohn’s disease, (CD) the biological era. Objective: This consensus aims to detail guidance most appropriate surgical procedures different IBD scenarios. In addition, it details indications perioperative management adult CD UC. Methods: Our was developed by colorectal surgeons gastroenterologists...
This is the first study on epidemiology of inflammatory bowel diseases (IBDs) in Rio Grande do Sul (RS), southernmost state Brazil with country's fifth largest population. Crohn's disease (CD) and ulcerative colitis (UC) are collectively termed IBDs. They have high incidence prevalence rates high-income countries, although recent years there has been a change classic geographical distribution IBDs, growing traditionally low-incidence regions.To estimate IBDs RS state, Brazil, between 2014...
Abstract Background Real-world data on the effectiveness and safety of ustekinumab (UST) in ulcerative colitis (UC) are lacking Latin America. In this study, we aimed to describe UST a real-world multicentre cohort Brazilian patients with UC. Methods We conducted retrospective observational including moderate severe UC (Total Mayo score 6-12, an endoscopic subscore 2 or 3) who received UST. The co-primary endpoints were clinical remission, defined as total ≤2 at 1 year, combined rectal...
Abstract Objective To describe the profile of surgeons who treat patients with inflammatory bowel disease as well characteristics care, unmet demands, and difficulties. Methods The research participants answered a Google Forms questionnaire. Results Of 99 participated in survey, 84.5% were coloproctologists, 40% from southeastern region Brazil, 77.7% male had been working for more than 19 years. Regarding healthcare sector, 63.6% worked both public private clinics, most clinically cared up...
Abstract Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions affecting the digestive tract. This study examines 188 IBD patients in a private healthcare service Canoas/RS, Brazil, aiming to understand their clinical profiles. Most were young adults, primarily white, with more women affected. Both CD UC commonly experienced diarrhea, but blood stools was prevalent UC. mostly affected small intestine, while involved...
Spectroscopic methods have already been used as effective tools in several studies involving the detection of cancer. Fourier transform infrared spectroscopy (FTIR) has applied discrimination cancer cells and tissues or blood patients with disease, observing that this technique requires use chemometric algorithms to obtain such results. The aim study was employ a partial least squares discriminant analysis (PLS-DA) FTIR data plasma samples from colorectal (RCC) healthy individuals....
Abstract Objective The present study describes the epidemiological profile of patients with colorectal cancer (CRC) from Hospital de Clínicas Passo Fundo, RS, Brazil, between January 1, 2007 and December 31, 2016. Method Retrospective analysis secondary data 1,001 Cancer Registry. Results Most subjects were Caucasian males, a mean age 63.68 years old. majority had incomplete elementary education married. In addition, 44.5% family history cancer. positive past or current alcohol intake...
Abstract Paget's disease most commonly affects the breast. Extramammary involvement is rare, and affected sites are vulva, anus, perianal region, axilla. The may progress to invasive adenocarcinoma or synchronous cancers. Due lack of distinctive features nonspecific presenting symptoms, be misdiagnosed as other conditions, thus delaying correct diagnosis. We report a case extramammary in region that initially presented an irregular, circumferential, scaling lesion with eczematous eruptions....
Abstract Background Anti-TNF therapy represented a landmark in medical treatment of ulcerative colitis (UC). There is lack data on the efficacy and safety these agents Brazilian patients. The present study aimed to analyze rates clinical endoscopic remission comparatively, between adalimumab (ADA) infliximab (IFX), patients with UC, evaluate factors associated after 1 year treatment. Methods A national retrospective multicenter (24 centers) was performed including UC treated anti-TNF...
Abstract Background There are few data on the quality-of-care for inflammatory bowel disease (IBD) in public, private or mixed hospitals, especially Latin America. The aim of study was to evaluated clinic and quality parameters their association with need ICU death Brazilian hospitals. Methods This a multicentre carried out 26 Four hundred eighty-eight admissions patients IBD were analysed between June 2021 October 2022. Results median stay length 6 days (0–121). age 38 years (16–87), 265...
Abstract Objective To evaluate the application of proactive pro-drug therapy (TDM) at week six in users infliximab ulcerative colitis patients and to analyze need for further disease optimization. Method This is a retrospective analysis that will be carried out simultaneously Hospital de Clínicas Passo Fundo Endoclin Diagnostic Center city Fundo, with secondary data collection between January 2020 May 2022. The sample included from both sexes, regardless age, who are being followed up...