A5070482925- Inflammatory Bowel Disease
- Microscopic Colitis
- Stoma care and complications
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Colorectal Cancer Surgical Treatments
- Cancer Genomics and Diagnostics
- Anorectal Disease Treatments and Outcomes
- Colorectal and Anal Carcinomas
- Piperaceae Chemical and Biological Studies
- Digestive system and related health
- Curcumin's Biomedical Applications
- Nutrition and Health in Aging
- Gut microbiota and health
- Women's cancer prevention and management
- Autoimmune and Inflammatory Disorders
- COVID-19 and healthcare impacts
- Urinary Tract Infections Management
- Antibiotic Resistance in Bacteria
- Gastroesophageal reflux and treatments
- Healthcare Systems and Reforms
- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Ginger and Zingiberaceae research
- Cancer-related Molecular Pathways
Universidade Federal de Alagoas
2012-2025
Hospital Universitario de Neiva
2008
The development and course of inflammatory bowel disease (IBD) are significantly influenced by inflammation oxidative stress. Antioxidant therapy is a promising therapeutic option to enhance the clinical results these individuals in this particular scenario. purpose study assess impact curcumin, with or without piperine, on cytokines, fecal calprotectin (CalF), stress enzymatic non-enzymatic indicators patients IBD.
Inflammatory bowel disease (IBD), comprising Crohn's (CD) and ulcerative colitis (UC), lacks a known etiology. Although clinical symptoms, imaging, colonoscopy are common diagnostic tools, fecal calprotectin (FC) serves as widely used biomarker to track activity. Metabolomics, within the omics sciences, holds promise for identifying progression biomarkers. This approach involves studying metabolites in biological media uncover pathological factors. The purpose of this study was explore...
Abstract The relationship between hypovitaminosis D and the development of inflammatory bowel disease (IBD) is well established in countries with high prevalence incidence IBD low exposure to solar ultraviolet radiation. However, only some studies included emerging countries, which have an increasing diverse climate social conditions. This cross-sectional study's purpose evaluate its activity patients treated at a reference service country. study analyzed medical records 113 from June 2022...
The aim of this study was to report circulating cell-free DNA using ALU247 and ALU247/ALU115 biomarkers in serum operated non-operated patients with colorectal cancer (CRC).To undertake this, 90 blood samples were collected, including 30 from healthy volunteers; 27 CRC 33 CRC-operated patients. Circulating verified through quantitative real-time PCR (qPCR) ALU115 primers.With regard the ALU115-qPCR biomarker, increased levels significant when compared control (p<0.05). Moreover, ALU247-qPCR...
Abstract Introduction Several clinical conditions imply the realization of a bowel ostomy, as treatment option. However, presence stoma is an important limitation in quality life ostomized patient. Aim To define epidemiological profile patients enrolled Ostomy Program from two reference services city Maceió, Alagoas, regarding gender, age, classification (as permanent or temporary), type ostomy with respect to segment used, and causes. Method This was descriptive cross-sectional study whose...
ABSTRACT BACKGROUND: Crohn’s disease and ulcerative colitis are the primary inflammatory bowel diseases (IBD), its pathogenesis is related to genetic environmental factors. Currently, diagnosis of IBD results in a multidisciplinary approach with significant disadvantages, such as invasive nature, time spent, fact that 10% patients remain without diagnostic classification. However, new methodologies analysis have emerged allowed expansion knowledge about IBD, metabolomics, study metabolites....
Abstract Introduction Inflammatory Bowel Diseases (IBD), represented by Crohn's disease (CD) and ulcerative colitis (UC) are chronic idiopathic inflammatory conditions involving the gastrointestinal tract. There several epidemiological studies that have shown an increased incidence of IBD worldwide. Objective To analyze profile patients with under biologic therapy, treated in a coloproctology outpatient clinic, Hospital Universitario Professor Alberto Antunes, Alagoas. Methods Retrospective...
Abstract Objective the aim of this study was to identify prevalence constipation in diabetic patients treated at endocrinology outpatient clinic Hospital Universitário Professor Alberto Antunes and PAM Salgadinho, from April August 2013. Methods a descriptive cross-sectional study, carried out through questionnaire using Rome III criteria 372 clinic. Results evaluated, frequency found 31.2% among patients. Females predominated sample (72.8%) as well for (80.2%). The incidence type II...
OBJETIVOS: Diagnosticar a presença do HPV anorretal em portadoras dessa afecção no trato genital inferior, através exame coloproctológico com anuscopia de alta resolução. MÉTODOS: Estudo observacional e transversal realizado um protocolo pesquisa, Hospital Universitário da UFAL Fevereiro Julho 2008, analisando 57 mulheres diagnóstico prévio infecção por submetendo-as uma avaliação RESULTADOS: A idade média variou 31,2 anos, seis pacientes eram gestantes, 59,6% cursaram apenas o 1º grau,...
Ultra-low-dose Spinal Anesthesia (SA) is the practice of employing minimal doses intrathecal agents so that only roots supply a specific area are anesthetized. The aim this study was to compare effectiveness and safety ultra-low-dose spinal anesthesia with Perineal Blocks (PB).A two-arm, parallel, double-blind randomized controlled trial comparing two anesthetic techniques (SA PB) for hemorrhoidectomy anal fistula surgery performed. primary outcomes were postoperative pain, complementation...
Abstract Background Anti-TNF therapy represented a landmark in medical treatment of ulcerative colitis (UC). There is lack data on the efficacy and safety these agents Brazilian patients. The present study aimed to analyze rates clinical endoscopic remission comparatively, between adalimumab (ADA) infliximab (IFX), patients with UC, evaluate factors associated after 1 year treatment. Methods A national retrospective multicenter (24 centers) was performed including UC treated anti-TNF...
Background and Objective: Healthcare-associated infections (HAIs) are the main cause of death in hospitalized individuals worldwide, related with preexisting disease invasive procedures. The present study aimed to identify microorganisms a immunosuppressed patient their antimicrobial resistance profile. Case report: A 33-year-old man Crohn's was admitted hospital for an enterostomy cholecystectomy, postoperative fever gastrointestinal bleeding. Infections urinary tract, into bloodstream...
Abstract Inflammatory bowel disease (IBD) is a problem that directly affects the quality of life patients suffering from this condition. Monitoring serum level infliximab (IFX) (TDM) an important tool for guiding therapeutic decisions in IBD patients. The purpose study was to determine significance quantitatively measuring IFX and antibody (ATI). Methods materials: Prospective observational involving 40 on therapy, including 14 Proactive (week 06 induction phase) 26 Reactive (maintenance...
Background: There are few data on the quality-of-care for inflammatory bowel disease (IBD) in public, private or mixed hospitals. Aim: To evaluated clinic and quality parameters their association with need ICU death Brazilian Methods: Multicentre study carried out 26 hospitals including 488 admissions of patients IBD were analyzed between June 2021 October 2022. Results: The median stay length was 6 days (0–121). age 38 years (16–87), 265 (54.6%) female; 339 (69.5%) had Crohn’s (CD) 149...
Colorectal neoplasm is one of the most common cancers in developed countries and its incidence has grown progressively. The currently used attempts to prognostic assessment are limited, since they restricted observation tumor morphology, such as TNM staging. quantification free DNA peripheral blood aims find a way relate it clinical status patients with cancer. OBJECTIVE: To evaluate prognosis colorectal cancer ALU247 fragments METHODS: We evaluated 79 following groups: Operated,...
A expressão de marcadores tumorais que se correlacionam com a agressividade dos cânceres vem sendo investigada vigor. Tendo o câncer colorretal significativa incidência, biomarcadores possam avaliá-lo quanto esse aspecto, não são exceção nesta investigação. OBJETIVO: estabelecer relação entre do acordo os estadiamentos TNM e Astler-Coller da Mucina1 (MUC1) em uma determinada amostra tumores. METODOLOGIA: foram examinados 36 colorretais ressecados pelos coloproctologistas Hospital...
ABSTRACT Background: Colorectal cancer (CRC) is the third most incident in world and second leading cause of death. Significant decreases incidence mortality can be achieved by reducing risk factors adhering to healthy lifestyle recommendations, as well screening for disease. Objective: To evaluate clinical nutritional profile individuals at medium screened CRC residing city Piranhas/Alagoas. Methods: Cross-sectional study conducted from September October 2020, with CRC, both sexes aged...
Abstract Background The surgery with total mesorectal excision recommended by R. J. Heald in 1982 is the gold standard. Rectal cancer (RC) has a morbidity rate ranging from 6 to 35%, and it can cause functional issues such as sexual, urinary, bowel dysfunction long term. Neoadjuvant chemoradiotherapy (CRT) been gaining ground patients lesions middle lower rectum. aim of present study experience reference service treatment RC. Patients Methods A retrospective involving 53 diagnosed RC between...
Caso Clínico Paciente do sexo masculino, de 2 anos e 8 meses, internado no serviço pediatria Hospital Universitário Professor Alberto Antunes, da Universidade Federal Alagoas (HUPAA–UFAL), com relato diarreia crônica havia mucossanguinolenta líquida, associada a sangue vivo. Negava vômitos, prurido, lesão pele, dor ou distensão abdominal, apresenta seletividade alimentar importante, desde tentativa introdução aos 6 meses diagnóstico autismo 1 ano idade. Após o início dos sintomas, genitora...
As doenças inflamatórias intestinais (DIIs) representam um problema que interfere diretamente na vida social e produtiva dos pacientes. O monitoramento terapêutico (TDM) do infliximab (IFX) é uma ferramenta importante para orientar a decisão terapêutica nos pacientes com DII.
Apresentação do Caso Um paciente de 35 anos, portador lesão cística retrorretal, foi submetido a abordagem cirúrgica por acesso posterior. No transoperatório, houve uma pequena violação reto distal cautério durante hemostasia, que rafiada utilizando-se fio absorvível monofilamentar. O recebeu alta no primeiro dia pós-operatório. Após três dias, relatou débito secreção com aspecto fecaloide pela ferida, e confirmada fístula pelo teste azul metileno. Indicou-se internamento hospitalar,...