A5028041992- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Stoma care and complications
- Tuberculosis Research and Epidemiology
- Gastrointestinal disorders and treatments
- Autoimmune and Inflammatory Disorders
- Celiac Disease Research and Management
- Natural product bioactivities and synthesis
- Pregnancy and Medication Impact
- Toxin Mechanisms and Immunotoxins
- Liver Diseases and Immunity
- Colorectal Cancer Screening and Detection
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Regulation
- Healthcare during COVID-19 Pandemic
- Parasitic Diseases Research and Treatment
- Biliary and Gastrointestinal Fistulas
- Health, Nursing, Elderly Care
- Diverticular Disease and Complications
- Biosimilars and Bioanalytical Methods
- Clinical Nutrition and Gastroenterology
- Trace Elements in Health
- Gastroesophageal reflux and treatments
Universidade Federal do Piauí
2015-2025
Universidade Estadual de Campinas (UNICAMP)
2006-2024
Ghent University
2023
Hospital Universitário da Universidade de São Paulo
2018-2019
AstraZeneca (United Kingdom)
2019
University of Waterloo
2019
University of Minho
2019
Universidade Federal Fluminense
2018
Universidade Estadual do Piau
2015
Chestnut Hill College
2014
ABSTRACT Significant progress has been obtained since the III Brazilian Consensus Conference on H. pylori infection held in 2012, Bento Gonçalves, Brazil, and justify a fourth meeting to establish updated guidelines current management of infection. Therefore, Núcleo Brasileiro para Estudo do Helicobacter e Microbiota (NBEHPM), association linked Federation Gastroenterology (FBG) its again RS, August 25-27, 2017. Twenty-six delegates, including gastroenterologists, endoscopists, pathologists...
To evaluate the demographic characteristics and clinical phenotypes of inflammatory bowel disease (IBD) in a geographic area Northeastern Brazil.This retrospective study was conducted at Hospital Federal University Piauí Brazil. Demographic IBD were analyzed relation to time diagnostic confirmation, which defined as date onset. Data collected between January 2011 December 2012 included all census patients 18 years age or older during that period for whom there confirmation Crohn's (CD),...
BACKGROUNDInflammatory bowel diseases (IBD) have been associated with a low quality of life (QoL) and negative impact on work productivity compared to the general population.Information about disease control, patient-reported outcomes (PROs), treatment patterns use healthcare resources is relevant optimizing IBD management. AIMTo describe QoL activity impairment (WPAI), among patients in Brazil.
Fifteen compounds, isolated from plants reputed as snake venom antidotes, belonging to different classes of natural products, were shown protect mice a significant degree against the lethal action Bothrops jararaca snakes. Administration was by oral route, one hour prior envenomation. The substances are nitrogen-free, low-molecular-weight compounds for which some kind biodynamic activity has previously been reported. fact that they mostly trivial, naturally-occurring should explain why used...
Abstract Background Biological therapy has revolutionized the treatment of inflammatory bowel disease (IBD); however, a subset patients still requires optimization to achieve therapeutic goals. This study aimed identify who underwent biological (TO) and compare their characteristics with those did not require such adjustments. Methods A retrospective was conducted using data from national patient registry GEDIIB (Brazilian Crohn's Colitis Organization). total 1,660 (CD) 530 ulcerative...
Abstract Background Vedolizumab (VDZ) is an α4β7 integrin antibody used to treat moderate-to-severe ulcerative colitis (UC) and Crohn’s disease (CD). We aimed assess the real-life long-term effectiveness safety of VDZ as a first- or second-line biological therapy identify predictors efficacy in large cohort patients with refractory difficult-to-treat UC. Methods This was multicenter, retrospective observational study including moderately-to-severely active UC who received for at least 12...
Abstract Background Ustekinumab (UST), an antibody targeting the p40 subunit of interleukin-12/23, has demonstrated efficacy in patients with Crohn’s disease (CD). However, comparative real-world data regarding positioning biologic therapies, particularly UST versus anti-tumour necrosis factor (TNF) agents, remain limited. This study aimed to compare effectiveness and safety anti-TNF agents biologic-naïve biologic-failure CD patients. Methods A multicentre retrospective cohort was conducted,...
Abstract Background Ulcerative Colitis (UC) and Primary Sclerosing Cholangitis (PSC) are interrelated chronic inflammatory diseases. Patients with both conditions at an elevated risk of colectomy, predominantly due to a higher incidence dysplasia colorectal cancer. Identify which patients colectomy can be crucial personalize their management. The primary objective was develop predictive model that accurately forecast risk. Methods A cross-sectional study conducted from multiple tertiary...
Objetivo: Avaliar casos possíveis ou prováveis de ansiedade e depressão em pacientes com Doenças Inflamatórias Intestinais acompanhamento ambulatorial um hospital universitário no nordeste brasileiro. Métodos: Estudo observacional transversal, realizado uma coorte Retocolite Ulcerativa (RCU) Doença Crohn (DC) do Brasil. Para avaliar nesses pacientes, foi utilizada a Escala Hospitalar Ansiedade Depressão (HADS). Resultados: Foram incluídos 148 58,1% DC 41,9% RCU, sendo 87 (58,8%) sexo...
Objetivos: Avaliar o tempo para diagnóstico das Doenças Inflamatórias Intestinais (DII) em um centro no nordeste do Brasil. Métodos: Estudo observacional, retrospectivo e transversal. Foram coletados dados nos prontuários eletrônicos hospital, incluindo pacientes acima de 18 anos atendidos 2013 a 2021 com confirmado Doença Crohn (DC) ou Retocolite Ulcerativa (RCU). Resultados: incluídos 678 pacientes, dos quais 346 tinham RCU 332 DC. O DII teve média 24,8 meses mediana 9,0 (variação 1 mês...
This survey was designed to evaluate the prevalence of Helicobacter pylori infection in asymptomatic children from families low and high socioeconomic status living two neighboring communities Teresina northeastern Brazil. The study included 303 children, 163 (53.8%) males 140 (46.2%) females, ranging age 6 months 12 years. determined by H. stool antigens test, which sensitivity specificity values for Brazilian were 96.9% 100%, respectively. rates 55.0% (93 169) 16.4% (22 134) status,...
Significant progress has been obtained since the Second Brazilian Consensus Conference on Helicobacter pylori Infection held in 2004, São Paulo, SP, Brazil, and justify a third meeting to establish updated guidelines current management of H. infection. The Third H was organized by Nucleus for Study Helicobacter, Department Federation Gastroenterology took place April 12-15, 2011, Bento Gonçalves, RS, Brazil. Thirty-one delegates coming from five regions one international guest, including...
Changes in dietary habits including increased intake of refined sugars and fats decreased fiber have been suggested as potential risk factors for the development inflammatory bowel diseases (IBD). Bioelectrical impedance analysis-derived phase angle (PhA) has gaining attention clinical evaluation nutritional status. In this study, we first time investigated relationship PhA ultra-processed food with oxidative stress, body composition biochemical parameters adult patients IBD.Body were...
Two alkamides, deca-2E,4E-dienoic acid isobutylamide (1) and octa-2E,4E-dienoic (2), were isolated from the roots of Cissampelos glaberrima (Menispermaceae). Their structures established by spectral physical methods. Traces two new decen-2-oic (3) decanoic (4), identified mass spectrometry.
The etiology of inflammatory bowel disease (IBD) is unknown, but it believed to be multifactorial. hygiene hypothesis proposes that better conditions would lead less infectious during childhood and favor the development immune-mediated diseases.To test in IBD by assessing environmental risk factors associated with different regions Brazil diverse socioeconomic indices.A multicenter case-control study was carried out 548 Crohn's (CD) 492 ulcerative colitis (UC) outpatients 416 healthy...
ABSTRACT BACKGROUND: Inflammatory bowel diseases (IBD) are chronic inflammatory affections of recurrent nature whose incidence and prevalence rates have increased, including in Brazil. In long term, they responsible for structural damage that impacts quality life, morbidity mortality patients. OBJECTIVE: To describe the profile physicians who treat IBD patients as well characteristics care, unmet demands difficulties. METHODS: A questionnaire containing 17 items was prepared sent to 286 from...
Understanding the treatment landscape of inflammatory bowel diseases (IBD) is essential for improving disease management and patient outcomes. Brazil largest Latin American country, it presents socioeconomic health care differences across its geographical regions. This country has highest increase in IBD incidence prevalence America, but information about clinical characteristics scarce.
Objetivo: determinar a frequência de infecção pelo Helicobacter pylori em pacientes com queixas dispépticas e avaliar concordância entre resultado do teste da urease exame histopatológico no diagnóstico infecção. Métodos: estudo observacional, transversal descritivo, realizado partir urease, laudo endoscópico submetidos à endoscopia digestiva alta (EDA) hospital universitário na cidade Teresina, Piauí. Resultados: amostra foi composta por 300 pacientes, sua maioria mulheres, média idade...