A5088334671- Inflammatory Bowel Disease
- Microscopic Colitis
- Colorectal Cancer Screening and Detection
- Autoimmune and Inflammatory Disorders
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Immunodeficiency and Autoimmune Disorders
- Endometriosis Research and Treatment
- Colorectal Cancer Surgical Treatments
- Tuberculosis Research and Epidemiology
- Cancer-related molecular mechanisms research
- Extracellular vesicles in disease
- Esophageal and GI Pathology
- Genetic factors in colorectal cancer
- Hematopoietic Stem Cell Transplantation
- Intraperitoneal and Appendiceal Malignancies
- Cytomegalovirus and herpesvirus research
- Bariatric Surgery and Outcomes
- Pulmonary Hypertension Research and Treatments
- Mycobacterium research and diagnosis
- Pregnancy and Medication Impact
- Women's cancer prevention and management
- Health Systems, Economic Evaluations, Quality of Life
- Diverticular Disease and Complications
- Medical Device Sterilization and Disinfection
Faculdade Ceres
2023-2025
Hospital de Base
2021
Beneficência Portuguesa de São Paulo
2015-2018
BACKGROUNDInflammatory bowel diseases (IBD) have been associated with a low quality of life (QoL) and negative impact on work productivity compared to the general population.Information about disease control, patient-reported outcomes (PROs), treatment patterns use healthcare resources is relevant optimizing IBD management. AIMTo describe QoL activity impairment (WPAI), among patients in Brazil.
Introduction: One of the problems that affects female population childbearing age or post-menopause is endometriosis, which a chronic condition between 2 and 17% women reproductive age. Objective: This study was conducted to verify knowledge participants, from private practices health insurance Unified Health System (SUS), have about aiming obtain data can support educational actions in public policies. Methods: followed prospective observational cross-sectional model, following STROBE...
Abstract Objective The incidence of adverse events in myeloablative transplant protocols is high refractory Crohn’s disease; this study used low doses cyclophosphamide. Fourteen patients were submitted to non-myeloablative autologous hematopoietic stem cell transplantation. Results average number days anemia (hemoglobin < 10 g/dL) was 5.4 ± 4.2 and 14 2.4 the mobilization conditioning phases, respectively. mean neutropenia (neutrophils 0.5 × 9 /L) phase 1.7 1.5 while it 7.6 1.4 phase....
Understanding the treatment landscape of inflammatory bowel diseases (IBD) is essential for improving disease management and patient outcomes. Brazil largest Latin American country, it presents socioeconomic health care differences across its geographical regions. This country has highest increase in IBD incidence prevalence America, but information about clinical characteristics scarce.
Abstract The Brazilian Organization for Crohn's Disease and Colitis (GEDIIB) established a national registry of inflammatory bowel disease (IBD). aim the study was to identify clinical factors associated with severity in IBD patients Brazil. A population-based risk model aimed at stratifying based on previous hospitalization, use biologics, need surgery ulcerative colitis (UC) Crohn’s (CD) complications CD. total 1179 (34.4 ± 14.7y; females 59%) were included: 46.6% UC, 44.2% CD, 0.9%...
The Cronkhite-Canada syndrome (CCS) was first reported in 1955, since then more than 500 cases have been reported, indicating an estimated incidence of one case per 1 million inhabitants. occurs predominantly male, with a ratio three males to two females. Because the rarity syndrome, there are no evidence-based therapies and treatments described include combination therapies, but none is consistently effective. Surgery usually reserved for treatment complications. Herein, we present...
The etiology of CD is unknown, but several proven riskfactors exist such as family history, smoking, oral contra-ceptives, diet and ethnicity. combination risk factors,and aberrant autoimmune response in the intestinal mucosawith endothelial dysfunction lead to digestive tract malfunc-tioning. Disease manifestations are heterogeneous mostpatients present with abdominal pain, diarrhea sometimeswith blood, weight loss, fever perianal lesions. Up 30%of
In real-world experience, the number of patients using vedolizumab as first-line biological therapy was low. We aimed to evaluate effectiveness and safety in mild-to-moderate Crohn's disease (CD) biologic-naïve patients.We performed a retrospective multicentric cohort study with who had clinical activity scores (Harvey-Bradshaw Index [HBI]) measured at baseline weeks 12, 26, 52, well last follow-up. Clinical response defined reduction ≥3 HBI, whereas remission HBI ≤4. Mucosal healing...
ABSTRACT Background: Fifty-five percent of Americans aged 50-65 are submitted to colonoscopy. For over 65-year, this number increases 64%. In Brazil, it is forecast that the population colonoscopy will grow, even though inadequate preparation still a major problem. Aim: To analyze quality new intestinal technique, Aquanet EC-2000®, compared oral Mannitol solution. Methods: This prospective longitudinal study enrolled 200 patients with indication for The sample was randomly allocated two...
Background Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBDs) with a remission-relapsing presentation symptomatic exacerbations that have detrimental impacts on patient quality of life associated high cost burden, especially in patients moderate-to-severe disease. The Real-world Data Moderate-to-Severe Inflammatory Bowel Disease Brazil (RISE BR) study was noninterventional designed to evaluate control, treatment patterns, burden health-related active IBD....
Colonoscopy procedures are commonly performed and have high success rates. However, poor or inadequate bowel preparation is one of the most common reasons for a repeated failed colonoscopy. We therefore an observational study followed by propensity score modeling to evaluate compare quality with use Aquanet cleansing devices (BCDs) versus oral sodium picosulfate solution.We prospective cross-sectional pre-endoscopic using BCD solution. Our major outcome interest was as measured through...
Abstract Background Treatment with high doses chemotherapy followed by autologous haematopoietic stem cell transplantation is promising for refractory Crohn’s disease patients no therapeutic option and at imminent risk of further surgeries. Objectives To evaluate the feasibility efficacy progenitor mobilization in a group preparing unselected single institution. This first study to disease. Methods Patients were selected according criteria European Bone Marrow Transplant Society. Results All...
Introdução A endometriose é uma doença que afeta a mulher em idade reprodutiva, e caracterizada por implante crescimento de tecido endometrial (glândulas e/ou estroma) fora da cavidade uterina. Os objetivos principais cirurgia pacientes com são retirar maior quantidade possível restabelecer anatomia normal pelve. Nos casos infiltrativa profunda, seja ela septo retovaginal, intestinal ou vesical, o benefício do tratamento cirúrgico muito grande.
Introdução A doença de Crohn pode afetar qualquer parte do trato digestivo, desde a boca até o ânus, e processo inflamatório da envolve toda espessura parede intestinal. As sequelas importantes incluem estenose, obstrução, fístula formação abscesso. intervenção cirúrgica é geralmente reservada pacientes com complicações relacionadas ou cuja refratária ao tratamento clínico.