- Sleep and related disorders
- Blood Pressure and Hypertension Studies
- Pharmaceutical Practices and Patient Outcomes
- Cardiac pacing and defibrillation studies
- Global Public Health Policies and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Systemic Lupus Erythematosus Research
- Medication Adherence and Compliance
- Telemedicine and Telehealth Implementation
- Global Maternal and Child Health
- Renal and Vascular Pathologies
- Antibiotic Use and Resistance
- Sleep and Wakefulness Research
- Healthcare Systems and Practices
- Migration, Health and Trauma
- Salivary Gland Disorders and Functions
- HIV-related health complications and treatments
- Chronic Disease Management Strategies
- Treatment of Major Depression
- HIV/AIDS Research and Interventions
- Ocular Diseases and Behçet’s Syndrome
- T-cell and B-cell Immunology
- Healthcare Policy and Management
- Spinal Fractures and Fixation Techniques
- Thermoregulation and physiological responses
Clinical Trial and Consulting
2019-2025
University of Lisbon
2004-2022
Hospital do Servidor Público Estadual
2021
Santa Paula Hospital
2021
Instituto de Saúde
2019
National Legal Medicine Institute
2013
BACKGROUNDInflammatory bowel diseases (IBD) have been associated with a low quality of life (QoL) and negative impact on work productivity compared to the general population.Information about disease control, patient-reported outcomes (PROs), treatment patterns use healthcare resources is relevant optimizing IBD management. AIMTo describe QoL activity impairment (WPAI), among patients in Brazil.
Hypoglycemia affects patient safety and glycemic control during insulin treatment of both type 1 (T1DM) 2 diabetes mellitus (T2DM). The Assessment Tool study in Brazil aimed to determine the proportion patients experiencing hypoglycemic events characterize awareness fear about hypoglycemia, among insulin-treated T1DM or T2DM patients.This was a non-interventional, multicenter study, with 6-month retrospective 4-week prospective evaluation events. Patients completed questionnaire at baseline...
In 2015, Portugal was the OECD country with highest reported consumption of BZD. Physician's perceptions and attitudes regarding BZD are main determinants related prescription habits. This study aimed to characterize beliefs Portuguese physicians prescription, management challenges, benefits, risks withdrawal effects A cross-sectional, observational online data collection through anonymous self-administered questionnaire. Physicians registered Medical Association were invited participate...
Background: Eventual relationships between the vascular function and transepidermal water loss (TEWL), in vivo , have not been entirely explored. By promoting local perfusion alterations through a well‐known challenge test, ‘tourniquet‐cuff occlusion’ manoeuvre, present study searches for other dynamical factors influencing cutaneous barrier, further exploring applicability of these flow‐related variables dermatological research. Methods: applying tourniquet‐cuff manoeuvre to group healthy...
Abstract Background Chronic benzodiazepine use is a challenge in primary care practice. Protocols to support safe discontinuation are still needed, especially countries with high utilization rates. Objectives To evaluate the feasibility, effectiveness, and safety of protocol setting. Methods Nonrandomized, single-arm interventional study, at units. Family physicians (FPs) recruited patients (18–85 years-old) dependence chronic daily ≥3 months. Patients dosages ≥30 mg diazepam-equivalent,...
Guidance about treatment-resistant depression (TRD) in Portugal is very limited, even though prevalence among the highest European countries. A questionnaire was conducted, followed by two advisory boards with seven Portuguese psychiatry experts, to characterize and discuss MDD TRD epidemiology, diagnosis, patient journey, treatment options, unmet clinical needs. Consensus reached on main issues. In daily practice, can be defined as moderate severe episodes insufficient improvement after...
With expanding indications for cardiac implantable electronic devices (CIEDs) capable of treating bradycardias, complex tachyarrhythmias and heart failure, the number patients requiring regular long-term specialized care is growing rapidly. Currently, routine face-to-face follow-up consultations with CIEDs are a significant burden on hospital services. Remote telemonitoring appears to offer safe effective alternative conventional in this area. The Medtronic CareLink Network enables remote...
Meningiomas account for 2.2% to 2.5% of all cerebral tumors, which only 2% are located in the foramen magnum. Foramen magnum meningiomas (FMMs) commonly found women, with a mean age at onset 52 years old. They generally behave more aggressively than other meningiomas.We performed epidemiological, anatomical and surgical analyses 20 patients diagnosed FMMs who underwent treatment from 1999 2019 Santa Paula Hospital Sao Paulo. This case series was compared previously published ones better...
The chronic use of benzodiazepine anxiolytics and hypnotics is a controversial issue it envisaged by most family physicians as health problem. Although benzodiazepines act rapidly are well tolerated, its prevalent raising clinical concerns. A narrative review was conducted to summarize indications, adverse effects risks associated with overuse. Available strategies discontinue these drugs at primary care setting also explored.Benzodiazepines main indications anxiety insomnia, when the...
Introdução: Em Portugal, a percentagem de hipertensos tratados e controlados é relativamente baixa. Desconhece-se relação dos determinantes socioeconómicos com o controlo tensional, particularmente nos imigrantes africanos. Objetivo: Comparar frequência identificar características associadas à hipertensão tratada não controlada, entre nativos portugueses (caucasianos) PALOP (negros).Material Métodos: Estudo transversal tratados, 40-80 anos, aleatorizados Cuidados Saúde Primários da região...
Introdução: A infeção do trato urinário é a complicação infeciosa mais comum no período pós transplante renal, estando sua frequência pouco caracterizada na população portuguesa. Este trabalho teve como objetivo determinar incidência de infeções e recorrentes em transplantados renais.Material Métodos: Tratou-se um estudo observacional coorte retrospetiva, com consulta dos processos clínicos doentes entre Janeiro 2004 Dezembro 2005, Hospital Santa Cruz, seguimento durante cinco anos ou até à...
Remote monitoring (RM) is a safe and effective alternative to in-office conventional follow-up. We aimed evaluate patient satisfaction with RM its impact on healthcare resources in population cardiac implantable electronic devices. Randomized, pragmatic, open-label controlled trial, adult wearers of cardioverter-defibrillator (ICD) or resynchronization therapy ICD (CRT-D), eligible for the CareLink® system. Patients newly implanted previous follow-up were randomized (control), followed 12...
With expanding indications for cardiac implantable electronic devices (CIEDs) capable of treating bradycardias, complex tachyarrhythmias and heart failure, the number patients requiring regular long-term specialized care is growing rapidly. Currently, routine face-to-face follow-up consultations with CIEDs are a significant burden on hospital services. Remote telemonitoring appears to offer safe effective alternative conventional in this area. The Medtronic CareLink Network enables remote...
Background: Late hospital presentation after acute stroke is one of the main reasons for low rates intravenous thrombolysis. This study aimed to investigate factors associated with delays an stroke. Methods: A cross-sectional consecutive patients from a Brazilian public university Stroke Center assisted May 2018 August 2019. Patients were interviewed structured questionnaire involving sociodemographic data, clinical history, context in which occurred and knowledge about disease. Results: Of...
Systemischer Lupus erythematodes (SLE), das Antiphospholipid-Syndrom (APS) und Sjögren-Syndrom (SS) sind heterogene Autoimmunerkrankungen. Schwere Ausprägungen sowie Therapieresistenz bzw. -unverträglichkeit gegenüber herkömmlichen Immunsuppressiva erfordern andere Behandlungsoptionen, d.h. biologische Arzneimittel kleine Moleküle. Unser Ziel war es, evidenz- praxisbasierte Leitlinien für die zulassungsüberschreitende Anwendung von Biologika bei SLE, APS SS zu definieren. Die Empfehlungen...
Introdução: Perdas de peso melhoram o controlo da tensão arterial em indivíduos hipertensos. As intervenções comportamentais para a perda parecem ser menos eficazes nos imigrantes origem africana (IOA). Os principais objetivos foram avaliar os efeitos no uma intervenção alimentar hipertensos nativos portugueses (NOP) e IOA; identificar fatores sucesso na peso; evolução dos conhecimentos adesão às recomendações alimentares.Material Métodos: Foram selecionados aleatoriamente medicados seguidos...