A5005050185- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- T-cell and Retrovirus Studies
- Veterinary Oncology Research
- Vector-Borne Animal Diseases
- Leptospirosis research and findings
- Brucella: diagnosis, epidemiology, treatment
- Probiotics and Fermented Foods
- Parasites and Host Interactions
- Animal health and immunology
- Virus-based gene therapy research
- Viral Infections and Vectors
- Inflammatory Bowel Disease
- Microbial infections and disease research
- Trace Elements in Health
- Animal Nutrition and Physiology
- Hematological disorders and diagnostics
- Vitamin D Research Studies
- Listeria monocytogenes in Food Safety
- Veterinary Medicine and Surgery
- Milk Quality and Mastitis in Dairy Cows
- Humic Substances and Bio-Organic Studies
- Dermatological diseases and infestations
- Menstrual Health and Disorders
- Veterinary Orthopedics and Neurology
Universidade Federal da Bahia
2018-2024
Hospital Ana Nery
2019-2023
Universidade Federal do Piauí
2010-2021
Universidade Estadual do Piau
2021
Brazilian Agricultural Research Corporation
2020
Universidade de São Paulo
2013-2019
Universidade Estadual de Londrina
2017-2019
Instituto de Medicina Avançada
2018-2019
Fundação de Amparo à Pesquisa do Estado do Piauí
2018
Instituto de Medicina Tropical
2013
Zoonotic leishmaniasis caused by Leishmania infantum is a disease of One Health concern since human and animal cases environmental damage are interconnected. L. has complex epidemiological cycle with multiple hosts, including mammals—humans, domestic, wild animals—and arthropod vectors. Knowledge on mammal infections in endemic areas crucial for developing control strategies. This work aimed to detect characterize infection domestic cats from where canine occur. No feline (FeL) had been...
Fifteen symptomatic and seven asymptomatic dogs infected naturally with Leishmania chagasi were examined in order to identify the presence of parasites changes heart lung. Histopathological, cytological, immunohistochemical analyses performed on samples lung tissues. An inflammatory reaction characterized by mononuclear, perivascular intermuscular infiltrates was observed both animals histopathological analysis heart. In lung, there thickening alveolar septa due congestion, edema,...
An infected host's Leishmania infantum load in blood is considered to be an estimate of his or her total parasite burden. Therefore, the measurement burden important identification factors involved control.Quantitative polymerase chain reaction was performed on samples from 625 patients with kala-azar consecutively admitted a reference hospital Teresina, Brazil. Primers were used amplify segment kDNA using TaqMan system. Non-parametric statistical tests applied.The median 499.2 amastigote...
Canine visceral leishmaniasis (CVL) diagnosis is still a challenge in endemic areas with limited diagnostic resources. This study proposes score the potential to distinguish positive CVL cases from negative ones. We studied 265 dogs that tested for on ELISA and parasitological tests. A ranging between 0 19 was recorded basis of clinical signs. Dogs had an overall higher positivity majority signs than did without or ehrlichiosis. Clinical such as enlarged lymph nodes (83.93%), muzzle/ear...
Leishmania RNA virus 1 (LRV1) is commonly found in South American parasites belonging to the subgenus Viannia, whereas 2 (LRV2) was previously thought be restricted Old-World pathogens of Leishmania.In this study, we investigated presence LRV2 strains (L.) infantum, causative agent visceral leishmaniasis (VL), originating from different hosts, clinical forms, and geographical regions.A total seventy-one isolates were screened for using semi-nested reverse transcription-polymerase chain...
Human visceral leishmaniasis, a parasitic disease of major public health importance in developing countries, is characterized by variable degrees severity anemia, but the mechanisms underlying this change peripheral blood have not been thoroughly explored. Here, we used an experimental model leishmaniasis C57BL/6 mice to explore basis anemia following infection with Leishmania donovani. 28 days post infection, showed bone marrow dyserythropoiesis myelogram, reduction TER119+ CD71-/+...
There is little evidence that current control strategies for canine leishmaniosis (CanL), the veterinary disease caused by L. infantum infection, are having a positive impact. This of critical importance because dogs primary reservoir and significant source parasite transmission to humans. Drugs intended primarily human use prohibited treatment CanL concerns over propagation resistant parasites. Although allopurinol effectively decreases burden in needs be maintained life. We hypothesized...
BACKGROUND Dogs are the main peridomiciliary reservoir of Leishmania infantum thus correct diagnosis infection is essential for control transmission and treatment as well. However, based on serological assays that not fully effective. OBJECTIVE We aimed to establish an effective assay L. infected dogs using Leishmania-derived recombinant antigens. METHODS derived rK39-, rK28-, rKR95-based enzyme-linked immunosorbent (ELISA) was standardized symptomatic asymptomatic infantum-infected dogs....
Abstract Efforts to control a zoonotic disease such as visceral leishmaniasis (VL) caused by Leishmania infantum can be successful if they rely on comprehensive data animal infection. In Bahia state, Brazil, human VL is endemic, yet some areas have no epidemiological canine L. infection and (CanL) date. We aimed perform an study describing the spatial distribution characterizing in two districts of municipality Muritiba, where cases occurred. Brazilian official serodiagnostic protocol (ELISA...
Prediction parameters of possible outcomes canine leishmaniasis (CanL) therapy might help with therapeutic decisions and animal health care. Here, we aimed to develop a diagnostic method predictive value by analyzing two groups dogs CanL, those that exhibited decrease in parasite load upon antiparasitic treatment (group: responders) maintained high despite the non-responders). The analyzed were parasitic determined q-PCR, hemogram, serum biochemistry immune system-related gene expression...
Evidence suggests that polymorphisms in the gene encoding a vitamin D receptor might affect blood pressure. The objective of this systematic review was to investigate association between hypertension and (Fok I) polymorphism. A literature search performed according PRISMA guidelines using MEDLINE®/PubMed, Scopus, Cochrane Library CENTRAL, SciELO, LILACS databases. quality case-control or cohort studies based on cross-sectional methodology evaluated Newcastle-Ottawa Scale protocol Loney...
Soro e rim de 75 suínos mestiços sem raça definida, criados em sistema extensivo abatidos Timon (MA) Teresina (Piauí), Brasil, duas cidades separadas pelo Rio Parnaíba um criação confinamento, filhos Landrace, Large White e/ou Duroc foram utilizados neste estudo. Das 150 amostras analisadas pela prova Soroaglutinação Microscópica (SAM), sete reagentes o sorovar Icterohaemorrhagiae (42,86%) foi mais frequente. Uma comparação entre os dois sistemas para examinar uma predisposição infecção...
Lipophosphoglycan (LPG) is the major surface glycoconjugate of Leishmania protozoan and has an important biological role in host-parasite interactions both midgut epithelium sand fly vector vertebrate macrophages. Canine leishmaniasis (CanL) a chronic infectious disease predominantly caused by infantum. An early accurate immunodiagnosis crucial for veterinary clinical practice control. In this work, we evaluated L. infantum LPG as antigen indirect enzyme-linked immunosorbent assay (ELISA)...
The objective of this study was to verify the occurrence ovine brucellosis using Agar Gel Immunodiffusion (AGID) and Polymerase Chain Reaction (PCR) techniques, as well identify main risk factors associated with infection in sheep flocks belonging municipalities microregion from Teresina, PI, Brazil.A total 100 urine blood samples were collected aged 6 months or older.The submitted conventional PCR examined by AGID technique.Of samples, 17 (17%) reactive test.In six (6%) positive.Risk B....