A5076884137- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Intestinal and Peritoneal Adhesions
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Diagnosis and treatment of tuberculosis
- Gut microbiota and health
- Nutrition and Health in Aging
- Body Composition Measurement Techniques
- Abdominal Surgery and Complications
- Agricultural and Food Sciences
- Stoma care and complications
- Colorectal Cancer Treatments and Studies
- Healthcare Systems and Reforms
- Fungal Infections and Studies
- Esophageal and GI Pathology
- Peptidase Inhibition and Analysis
- Psoriasis: Treatment and Pathogenesis
- Venous Thromboembolism Diagnosis and Management
- Vascular Tumors and Angiosarcomas
- Pregnancy and Medication Impact
- Autoimmune and Inflammatory Disorders
- Electrical and Bioimpedance Tomography
Universidade Estadual de Campinas (UNICAMP)
2018-2025
Abstract Background Vedolizumab (VDZ) is an α4β7 integrin antibody used to treat moderate-to-severe ulcerative colitis (UC) and Crohn’s disease (CD). We aimed assess the real-life long-term effectiveness safety of VDZ as a first- or second-line biological therapy identify predictors efficacy in large cohort patients with refractory difficult-to-treat UC. Methods This was multicenter, retrospective observational study including moderately-to-severely active UC who received for at least 12...
ABSTRACT Background: The most efficient way to prevent complications from inflammatory bowel disease (IBD) is provide patients with optimized care. Nonetheless, in Brazil, there no validated methodology for evaluating health services recognized as comprehensive care units (CCU), making it difficult assess the quality of provided. Objective: To understand current scenario, map distribution centers and identify strengths weaknesses, considering local regional characteristics. Methods: study...
Abstract Background Real-world data on the effectiveness and safety of ustekinumab (UST) in ulcerative colitis (UC) are lacking Latin America. In this study, we aimed to describe UST a real-world multicenter cohort Brazilian patients with UC. Methods We conducted retrospective observational including moderate-to-severe UC (total Mayo score 6–12, an endoscopic subscore 2 or 3) who received UST. The co-primary endpoints were clinical remission, defined as total ≤2 at 1 year, combined rectal...
Approximately 25% of patients with inflammatory bowel disease (IBD) develop the during childhood or adolescence and treatment aims to control active symptoms prevent long-term complications. The management Crohn's (CD) ulcerative colitis (UC) can be especially challenging in children adolescents, related particularities that may affect growth, development, puberty.This consensus provide guidance on most effective medical surgical pediatric CD UC.Experts Pediatric IBD representing Brazilian...
Background: Despite optimized medical therapy, contemporary risk of surgery in inflammatory bowel diseases (IBD) after 10 years diagnosis is 9.2% patients with ulcerative colitis (UC) and 26.2% Crohn’s disease, (CD) the biological era. Objective: This consensus aims to detail guidance most appropriate surgical procedures different IBD scenarios. In addition, it details indications perioperative management adult CD UC. Methods: Our was developed by colorectal surgeons gastroenterologists...
The EncephalApp Stroop Test was developed to more easily diagnose minimal hepatic encephalopathy (MHE). A cut-off of >274.9sec (ONtime+OFFtime) reached a 78% sensitivity and 90% specificity in the validation study, but it has been poorly studied Brazil. We aim analyze usefulness this diagnostic method describe value screen MHE Brazil.In cross-sectional single-center three positive psychometric tests defined diagnosis as gold standard. evaluated gender, age, education, familiarity with...
Bacterial infection is present in up to 30% of hospitalized cirrhotic patients. It can lead, even after its resolution, organ dysfunction and acute-on-chronic liver failure (ACLF). the precipitating factor ACLF one third cases main cause mortality patients with cirrhosis.The aim this study was evaluate prevalence identify early risk factors for severe death cirrhosis bacterial infection.This a prospective observational study. Hospitalized were included. Clinical laboratory data their...
Malnutrition among inflammatory bowel disease (IBD) subjects is well documented in literature and may emerge from factors including inadequate dietary intake, malabsorption activity. The aim of this study was to complete a comprehensive nutrition assessment explore what possibilities help bring better quality life for IBD subjects.
Background/Aims Inflammatory bowel disease (IBD) are chronic entities characterized by local and systemic inflammation may be associated with thrombosis. The aim of this study was to identify the prevalence thromboembolic events (TEE) in hospitalized IBD patients risk factors for their occurrence. Methods This retrospective, single-center included treated at a Brazilian referral unit between 2004 2014. Patients more than 48 hours due active who did not receive prophylaxis TEE during...
Abstract Background In Brazil there is no methodology for evaluating health services recognized as Comprehensive Care Units (CCU), making it difficult to assess the quality of care provided IBD patients. Aims: Map distribution this units and identify strengths weaknesses, considering local regional characteristics with a view proposing ranking system Brazilian centers. Methods The study was carried out in three phases. First, GEDIIB developed 22 questions characterize CCU Brazil. questionary...
Abstract Background Real-world data on the effectiveness and safety of ustekinumab (UST) in ulcerative colitis (UC) are lacking Latin America. In this study, we aimed to describe UST a real-world multicentre cohort Brazilian patients with UC. Methods We conducted retrospective observational including moderate severe UC (Total Mayo score 6-12, an endoscopic subscore 2 or 3) who received UST. The co-primary endpoints were clinical remission, defined as total ≤2 at 1 year, combined rectal...
Abstract Introduction and Objectives Certolizumab Pegol (CZP) is an anti-TNF agent approved in Brazil for Crohn's disease (CD). There a lack of data Latin America detailing real-world experiences with CZP. The primary objective was clinical remission weeks 26 54. secondary endpoints were response 54, endoscopic remission, biological switch rates, rates CD-related surgery, persistence treatment over time, adverse events. Remission defined as HBI ≤4 ≥3 points reduction HBI, respectively....
The differential diagnosis of hepatic focal lesions is challenging because the etiology can be inflammatory, infectious, and even neoplastic. A rare cause metastatic liver nodules cardiac angiosarcoma. We report a case this tumor, which was diagnosed only after autopsy. 26-year-old Caucasian man admitted for progressive dyspnea cough over past 3 weeks. Physical examination showed hypophonetic heart sounds. Laboratory analysis demonstrated anemia elevated inflammatory markers, despite normal...
Phase angle through electrical bioimpedance as a predictor of cellularity in inflammatory bowel disease