A5069491929- Inflammatory Bowel Disease
- Microscopic Colitis
- Adolescent and Pediatric Healthcare
- Diagnosis and treatment of tuberculosis
- Tuberculosis Research and Epidemiology
- Gastrointestinal disorders and treatments
- Liver Diseases and Immunity
- Mycobacterium research and diagnosis
- Childhood Cancer Survivors' Quality of Life
- COVID-19 and healthcare impacts
- Gastrointestinal Bleeding Diagnosis and Treatment
- COVID-19 and Mental Health
- Chronic Lymphocytic Leukemia Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pediatric Pain Management Techniques
- Immunodeficiency and Autoimmune Disorders
- Abdominal Surgery and Complications
- Lipid metabolism and disorders
- Aortic Disease and Treatment Approaches
- COVID-19 Clinical Research Studies
- Autoimmune and Inflammatory Disorders
- Eosinophilic Esophagitis
- Health Systems, Economic Evaluations, Quality of Life
- Acute Lymphoblastic Leukemia research
- Clostridium difficile and Clostridium perfringens research
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2011-2023
Universidade de São Paulo
2019-2023
Hospital São Paulo
2023
Hospital Israelita Albert Einstein
2011-2023
Universidade Brasil
2021
Universidade Estadual de Campinas (UNICAMP)
2012
Lurie Children's Hospital
1995
To assess the possible factors that influence sleep quality in adolescents with and without chronic immunosuppressive conditions quarantined during coronavirus disease 2019 (COVID-19) pandemic.
Approximately 25% of patients with inflammatory bowel disease (IBD) develop the during childhood or adolescence and treatment aims to control active symptoms prevent long-term complications. The management Crohn's (CD) ulcerative colitis (UC) can be especially challenging in children adolescents, related particularities that may affect growth, development, puberty.This consensus provide guidance on most effective medical surgical pediatric CD UC.Experts Pediatric IBD representing Brazilian...
Introduction: Among healthy adolescents, school closures and home confinement were shown to increase unhealthier eating habits sedentary behavior. It remains unknown which extent the pandemic has impacted lifestyle of adolescents with chronic conditions. Thus, aim this study is report on impact COVID-19 outbreak behavior among multiple conditions (n = 347) from a tertiary, referral hospital vs. peers. Methods: This observational was conducted in São Paulo (Brazil) between July October 2020,...
Therapeutic drug monitoring (TDM) during induction therapy with anti-tumor necrosis factor drugs has emerged as a strategy to optimize response these biologics and avoid undesired outcomes related inadequate exposure. This study aimed describe clinical, biological, endoscopic remission rates at six months in Brazilian inflammatory bowel disease (IBD) patients following proactive TDM algorithm guided by IFX trough levels (ITL) antibodies (ATI) induction, week six. A total of 111 IBD were...
Anti-tumor necrosis factor (anti-TNF) drugs have been the mainstay therapy for moderate to severe inflammatory bowel disease (IBD) over past 25 years. Nevertheless, these are associated with serious opportunistic infections like tuberculosis (TB). Brazil is ranked among 30 countries highest incidence of TB in world. This study aimed at identifying risk factors development active and describing clinical characteristics outcomes IBD patients followed a tertiary referral center Brazil.We...
We report the clinical case of an infant with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection gastrointestinal signs and symptoms, predominantly vomiting. The patient also had colic, poor feeding, mild diarrhea rhinorrhea without fever. child evidence altered coagulation, increased interleukin 10, moderate dehydration she was admitted to pediatric intensive care unit. Simultaneously, diagnosed as Clostridioides difficile infection, which possibly may have facilitated...
This clinical case illustrates a rare and life‐threatening presentation of celiac disease (CD), crisis with neurological symptoms. The diagnosis should be included in the differential some types diarrhea serious metabolic disorders to prevent future complications. A large number patients remain undiagnosed for years, especially when form is atypical. They are exposed risks acute complications, as reported here, or chronic such infertility, osteoporosis lymphoma.
Objective: To estimate the cost-effectiveness of three alternative dietetic strategies for cow’s milk allergy in Brazil: 1) using an extensively hydrolyzed casein formula (eHCF; Nutramigen) as a first-line formula, but switching to amino acid (AAF) if infants remain symptomatic; 2) AAF and then eHCF after 4 weeks once are symptom-free, back become 3) keeping all on that formula. The analysis was conducted from perspective Brazilian public health care system, Sistema Único de Saude. Methods:...
The COVID-19 pandemic impacts on eating habits among adolescents may be more relevant in pediatric patients with immunocompromised chronic diseases. This case-control study conducted between June and October 2020 aimed to: (i) describe dietary patterns of conditions compared to healthy controls (ii) determine associations food consumption, health-related quality life (HRQL) sleep during the pandemic. Participants (184 58 adolescents, aged 14.3 [SD 2.5]) responded HRQL validated instruments...
Inflammatory bowel diseases (IBD), comprising Crohn's disease and ulcerative colitis, are chronic inflammatory of the gastrointestinal tract that often have their onset among adolescents young adults (AYA). IBD characterized by episodes active interspersed with periods remission, its activity is inversely correlated health-related quality life (HRQL).This study aimed to determine whether AYA in remission or low would exhibit HRQL similar age-matched healthy individuals, demographic factors...
BACKGROUND: The main ophthalmologic extraintestinal manifestations (EIM) in inflammatory bowel disease (IBD) patients are episcleritis, uveitis and scleritis. Uncommon ophtalmic involvement can occur may be related to adverse events of anti-TNF therapy. As the signs symptoms similar, differentiating these changes becomes a challenge for physician. aim this report is describe 3 cases complications (2 opportunistic infections 1 effect) during treatment. METHODS: Data from IBD Unit...
<b><i>Introduction:</i></b> The coronavirus disease 2019 (COVID-19) pandemic has increased concern regarding SARS-CoV-2 infection in inflammatory bowel (IBD) patients, especially those on immunosuppressive therapies or with active disease. There are limited reports describing the clinical features of COVID-19 an IBD population, and impact immunosuppression severity remains unclear. <b><i>Case Report:</i></b> A 33-year-old female patient a long...
Background Crohn's disease (CD) is a chronic inflammatory and relapsing that can affect any segment of the gastrointestinal tract. A significant percentage these patients suffer an aggressive course, refractory to conventional clinical therapy . Surgery may be required, however tends recur after resection. Aim Describe potential benefit autologous hematopoietic stem cell with T-lymphocyte-depletion as treatment for CD patients. Evaluate its efficacy, safety, toxicity adverse events primary...
ABSTRACT Purpose To report on the impact of COVID-19 outbreak eating habits and sedentary behavior among adolescents with multiple chronic conditions (n=347) from a tertiary, referral hospital vs . healthy peers. Methods This observational study was conducted in Sao Paulo (Brazil) between July October 2020, period which set social distancing measures to contain pandemic. Results The main findings this were that showed important changes (e.g., less often consumption convenience foods more...