A5007255155- Clinical Nutrition and Gastroenterology
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Nutrition and Health in Aging
- COVID-19 Clinical Research Studies
- Kawasaki Disease and Coronary Complications
- Child Nutrition and Water Access
- Intensive Care Unit Cognitive Disorders
- Neonatal Respiratory Health Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Child Nutrition and Feeding Issues
- Body Composition Measurement Techniques
- Electrolyte and hormonal disorders
- Mechanical Circulatory Support Devices
- Childhood Cancer Survivors' Quality of Life
- COVID-19 Impact on Reproduction
- Emergency and Acute Care Studies
- Abdominal Surgery and Complications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Antimicrobial Resistance in Staphylococcus
- Organ Transplantation Techniques and Outcomes
- Healthcare cost, quality, practices
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2024
Universidade de São Paulo
2014-2024
Associação de Medicina Intensiva Brasileira
2020
SUPERA Park of Innovation and Technology of Ribeirão Preto
2017
Centro Universitário das Faculdades Metropolitanas Unidas
2009-2016
National Influenza Center
2014
Instituto Superior Miguel Torga
2014
Universidade Federal de São Paulo
2014
Instituto de Patologia da Coluna
2013
Hospital Universitário da Universidade de São Paulo
2000
We report the case of an 11-year-old child with multisystem inflammatory syndrome in children (MIS-C) related to COVID-19 who developed cardiac failure and died after 1 day admission hospital for treatment. An otherwise healthy female African descent, patient was admitted paediatric intensive care unit (ICU) cardiovascular shock persistent fever. Her initial symptoms were fever 7 days, odynophagia, myalgia, abdominal pain. On ICU, presented respiratory distress, comprising tachypnoea...
COVID-19 in children is usually mild or asymptomatic, but severe and fatal paediatric cases have been described. The pathology of not known; the proposed pathogenesis for includes immune-mediated mechanisms direct effect SARS-CoV-2 on tissues. We describe autopsy findings five provide mechanistic insight into involved disease.Children adolescents who died with between March 18 August 15, 2020 were autopsied a minimally invasive method. Tissue samples from all vital organs analysed by...
To assess whether the combination of daily evaluation and use a spontaneous breathing test could shorten duration mechanical ventilation as compared with weaning based on our standard care. Secondary outcome measures included extubation failure rate need for noninvasive ventilation.A prospective, randomized controlled trial.Two pediatric intensive care units at university hospitals in Brazil.The trial involved children between 28 days 15 yrs age who were receiving least 24 hrs.Patients...
To assess the outcomes of pediatric patients with laboratory-confirmed coronavirus disease (COVID-19) or without multisystem inflammatory syndrome in children (MIS-C). This cross-sectional study included 471 samples collected from 371 (age<18 years) suspected having severe acute respiratory 2 (SARS-CoV-2) infection. The group comprised 66/371 (18%) COVID-19 patients: 61 (92.5%) tested positive on real-time reverse transcription-polymerase chain reaction tests for SARS-CoV-2, and 5 (7.5%)...
Critical illness has a major impact on the nutritional status of both children and adults. A retrospective study was conducted to evaluate incidence hospital malnutrition at pediatric tertiary intensive care unit (PICU). Serum concentrations IL-6 in subgroups well-nourished malnourished patients were also evaluated an attempt identify those with potential risk. total 1077 enrolled. Nutritional by Z-score (weight for age). We compared mortality, sepsis incidence, length stay nourished...
To establish disease severity at admission can be performed by way of the mortality prognostic. Nowadays prognostic scores make part quality control and research. The Pediatric Risk Mortality is one used in pediatric intensive care units.The purpose this study utilization risk to determine factors a tertiary units.Retrospective cohort study, period year, general unit. corresponding first 24 hours hospitalization were recorded; additional data collected characterize population.359 patients...
Nutrition therapy (NT) is essential for the care of critically ill children. Inadequate feeding leads to malnutrition and may increase patient's risk morbidity mortality. The aim this study was describe NT used in a tertiary pediatric intensive unit (PICU).The authors evaluated administered 90 consecutive patients who were hospitalized 7 days PICU Instituto da Criança, Hospital das Clínicas, Universidade de São Paulo, Brazil. established according protocol provided by institution's team....
Nosocomial candidaemia is associated with high mortality rates in critically ill paediatric patients; thus, the early detection and identification of infectious agent crucial for successful medical intervention. The PCR-based techniques have significantly increased Candida species bloodstream infections. In this study, a multiplex nested PCR approach was developed neonatal intensive care patients. DNA samples from blood 54 neonates children hospitalised units suspected were evaluated by...
Focused echocardiographic examinations performed by intensivists and emergency room physicians can be a valuable tool for diagnosing managing the hemodynamic status of critically ill children. The aim this study was to evaluate learning curve achieved using theoretical practical training program designed enable pediatric conduct targeted echocardiograms.Theoretical sessions were conducted with 16 intensivist/emergency physicians. included qualitative analyses left ventricular (LV) right (RV)...
Objectives: Children admitted to PICUs often present with or develop respiratory failure that requires mechanical ventilation. We prospectively identified children three general PICUs, the goal of identifying risk factors for mortality. Design: Prospective multicenter observational study. Setting: Three two in São Paulo and one Curitiba, Brazil. Patients: aged between 1 month 15 years, consecutively August 2008 July 2010, acute lung injury distress syndrome developed at least 12 hours after...
Introduction Undernutrition is a common concern among critically ill children and adolescents in the hospital setting. Inadequate delivery of nutrition therapy (NT) can significantly contribute to prevalence undernutrition pediatric intensive care units (PICUs). Objective To assess impact interruptions on volume NT delivered with basal chronic conditions, as well calories proteins provided, during acute phase PICU. Methods A cohort patients conditions was analyzed evaluate administration...
Nutrition markers may be useful for diagnosis and monitoring and, also, as additional indicators of estimating death risk. We tested the association body composition (mid-upper arm circumference phase angle) with pediatric intensive care unit (PICU) length stay mortality in critically ill patients.Data from children aged 2 months-18 years were collected, bioelectrical impedance was performed to obtain angle. Severity evaluated by scoring Pediatric Index Mortality. Descriptive statistics...
To analyze the nutritional status of pediatric patients after orthotopic liver transplantation and relationship with short-term clinical outcome.Anthropometric evaluations 60 children adolescents transplantation, during first 24 hours in a tertiary intensive care unit. Nutritional was determined from Z score for following indices: weight/age height/age or length/age, weight/height weight/length, body mass index/age, arm circumference/age triceps skinfold/age. The severity disease evaluated...
OBJECTIVES: Developing malnutrition during hospitalization is well recognized worldwide, and children are at a relatively higher risk for than adults.Malnutrition can lead to immune dysfunction, which associated with mortality rate due sepsis, the most frequent cause of death in pediatric intensive care units (PICUs).The aim this study was investigate whether malnourished patients more likely have relative or absolute lymphopenia and, consequently, worse prognoses.METHODS: We enrolled 14...
To evaluate mortality in adolescents and young adult patients with chronic diseases followed a Latin American tertiary hospital.A cross-sectional retrospective study was performed tertiary/academic hospital the state of São Paulo, Brazil. Death occurred 529/2850 (18.5%) diseases, 25/529 (4.7%) were excluded due to incomplete medical charts. Therefore, 504 deaths evaluated.Deaths 316/504 (63%) early adolescent 188/504 (37%) late adolescent/young patients. Further comparisons between (n=316)...