A5031144522- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Autopsy Techniques and Outcomes
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Respiratory Support and Mechanisms
- Mosquito-borne diseases and control
- Ultrasound in Clinical Applications
- Leptospirosis research and findings
- COVID-19 diagnosis using AI
- Insect Pest Control Strategies
- Magnetic Properties and Applications
- Thermal Regulation in Medicine
- Viral Infections and Outbreaks Research
- Insect Resistance and Genetics
- Growth and nutrition in plants
- Zoonotic diseases and public health
- Kawasaki Disease and Coronary Complications
- Microstructure and Mechanical Properties of Steels
- Dengue and Mosquito Control Research
- Dermatological and COVID-19 studies
- Infectious Encephalopathies and Encephalitis
- Data-Driven Disease Surveillance
- COVID-19 Impact on Reproduction
- Polymer-Based Agricultural Enhancements
Universidade de São Paulo
2020-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2019-2021
Universidade Estadual Paulista (Unesp)
1981-2021
Universidade de Sorocaba
2019-2021
Universidade Federal de Ouro Preto
2017
São Paulo State Technological College
2016
Brazil ranks high in the number of coronavirus disease 19 (COVID-19) cases and COVID-19 mortality rate. In this context, autopsies are important to confirm disease, determine associated conditions, study pathophysiology novel disease. The aim was assess systemic involvement COVID-19. order follow biosafety recommendations, we used ultrasound-guided minimally invasive autopsy (MIA-US), present results 10 initial autopsies.We MIA-US for tissue sampling lungs, liver, heart, kidneys, spleen,...
We report the case of an 11-year-old child with multisystem inflammatory syndrome in children (MIS-C) related to COVID-19 who developed cardiac failure and died after 1 day admission hospital for treatment. An otherwise healthy female African descent, patient was admitted paediatric intensive care unit (ICU) cardiovascular shock persistent fever. Her initial symptoms were fever 7 days, odynophagia, myalgia, abdominal pain. On ICU, presented respiratory distress, comprising tachypnoea...
Abstract The ability of the new coronavirus SARS‐CoV‐2 to spread and contaminate is one determinants COVID‐19 pandemic status. has been detected in saliva consistently, with similar sensitivity that observed nasopharyngeal swabs. We conducted ultrasound‐guided postmortem biopsies fatal cases. Samples salivary glands (SGs; parotid, submandibular, minor) were obtained. analyzed samples using RT‐qPCR, immunohistochemistry, electron microscopy, histopathological analysis identify elucidate...
COVID-19 in children is usually mild or asymptomatic, but severe and fatal paediatric cases have been described. The pathology of not known; the proposed pathogenesis for includes immune-mediated mechanisms direct effect SARS-CoV-2 on tissues. We describe autopsy findings five provide mechanistic insight into involved disease.Children adolescents who died with between March 18 August 15, 2020 were autopsied a minimally invasive method. Tissue samples from all vital organs analysed by...
Abstract Background Pulmonary involvement in COVID-19 is characterized pathologically by diffuse alveolar damage (DAD) and thrombosis, leading to the clinical picture of Acute Respiratory Distress Syndrome. The direct action SARS-CoV-2 lung cells dysregulated immuno-coagulative pathways activated ARDS influence pulmonary severe COVID, that might be modulated disease duration individual factors. In this study we assessed proportions different pathology patterns patients along evolution...
Abstract Background Multi‐organ damage is a common feature of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, going beyond the initially observed pneumonia. Evidence that testis also compromised growing. Objective To describe pathological findings in testes from fatal cases COVID‐19, including detection viral particles and antigens, inflammatory cell subsets. Materials methods Postmortem testicular samples were obtained by percutaneous puncture 11 deceased men...
Background New strategies for collecting post-mortem tissue are necessary, particularly in areas with emerging infections. Minimally invasive autopsy (MIA) has been proposed as an alternative to conventional (CA), promising results. Previous studies using MIA addressed the cause of death adults and children developing countries. However, none these was conducted undergoing infectious disease epidemic. We have recently experienced epidemic yellow fever (YF) Brazil. Aiming provide new...
Brain abnormalities are a concern in COVID-19, so we used minimally invasive autopsy (MIA) to investigate it, consisting of brain 7T MR and CT images tissue sampling via transethmoidal route with at least three fragments: the first one for reverse transcription polymerase chain reaction (RT-PCR) analysis remaining fixed stained hematoxylin eosin. Two mouse monoclonal anti-coronavirus (SARS-CoV-2) antibodies were employed immunohistochemical (IHC) reactions.
0 -0 , III Thais Mauad I Paulo Hila ´rio do Nascimento Saldiva
Introduction COVID-19 affects patients of all ages. There are few autopsy studies focusing on the younger population. We assessed an cohort aiming to understand how age influences pathological outcomes in fatal COVID-19. Methods This study included autopsied patients, aged 6 months 83 years, with confirmed 2020–2021. collected tissue samples from deceased using a minimally invasive protocol and data following systematic approach. Results Eighty-six were included, median 55 years (IQR...
The encapsulation of pesticides in systems responsive to enzymes allow for greater selectivity and specificity pest control, addition contributing reducing the impact on nontarget organisms environment. Therefore, objective this study was investigate synthesis zein nanoparticles loaded with a mixture botanical insecticides release triggered by proteolytic found midguts insects larvae. carried out using antisolvent precipitation method. Nanoformulations were characterized according size, zeta...
Minimally invasive autopsies, also known as minimally tissue sampling (MITS), have proven to be an alternative complete diagnostic autopsies (CDAs) in places or situations where this procedure cannot performed. During the coronavirus disease 2019 (COVID-19) pandemic, CDAs were suspended by March 2020 Brazil reduce biohazard. To contribute understanding of COVID-19 pathology, we conducted ultrasound (US)-guided MITS a strategy.This case series study includes 80 performed patients with...
Abstract Objective: To create a protocol for performing minimally invasive autopsies (MIA) in detecting deaths from arboviruses and report preliminary data its application Ceará state, Brazil. Methods: Training was provided to medical pathologists on MIA. Results: A established MIA, defining criteria sample collection, storage methods, diagnoses be carried out according the type of biological sample; 43 MIAs were performed three months. Of these, 21 (48.8%) arrived at Death Verification...
Amaro N. Duarte-Neto1Maria de Fátima Marinho2Lucia P. Barroso3Carmen D. Saldiva André3*Luiz Fernando F. da Silva1Marisa Dolhnikoff1Paulo Afonso André1Catia M. Minto4Catia S. Moura1Thábata Leite1Jair Theodoro Filho1Renata Aparecida Almeida Monteiro1Philip Setel5Martin W. Bratschi5Robert Mswia5Paulo Hilário Saldiva1Ana Luiza Bierrenbach2
The effect of carbon content on the magnetic ageing index and Vickers hardness evolution annealed samples 2%Si non-oriented grain electrical steel was studied. Samples with 40 60ppm were subjected at temperatures 200 225ºC, respectively. During treatment, cycle interrupted several time intervals in order to obtain core loss determine hardness. precipitates characterized using scanning electron microscope (SEM). Using software MatCalc, computer simulations ε-carbide precipitation performed...