A5018753970- Cancer Cells and Metastasis
- Dental Implant Techniques and Outcomes
- Oral and Maxillofacial Pathology
- Cancer Diagnosis and Treatment
- Oral microbiology and periodontitis research
- Periodontal Regeneration and Treatments
- Oral Health Pathology and Treatment
- Dental Radiography and Imaging
- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- PI3K/AKT/mTOR signaling in cancer
- Medical Imaging and Pathology Studies
- Ear and Head Tumors
- RNA modifications and cancer
- Cancer Research and Treatments
- Dermatological and COVID-19 studies
- SARS-CoV-2 detection and testing
- Cancer-related molecular mechanisms research
- Neuroblastoma Research and Treatments
- Hedgehog Signaling Pathway Studies
- Tumors and Oncological Cases
- Genital Health and Disease
- Brain Metastases and Treatment
- MicroRNA in disease regulation
University of Michigan
2020-2022
Universidade de São Paulo
2016-2018
Abstract The ability of the new coronavirus SARS‐CoV‐2 to spread and contaminate is one determinants COVID‐19 pandemic status. has been detected in saliva consistently, with similar sensitivity that observed nasopharyngeal swabs. We conducted ultrasound‐guided postmortem biopsies fatal cases. Samples salivary glands (SGs; parotid, submandibular, minor) were obtained. analyzed samples using RT‐qPCR, immunohistochemistry, electron microscopy, histopathological analysis identify elucidate...
Background Mucoepidermoid carcinoma ( MEC ) is the most common salivary gland malignancy and successfully treated by surgery radiation. However, some patients have recurrent tumours in these cases, few treatments options are available. Cancer stem cells CSC been observed isolated from different solid based on expression of cell markers. These associated with tumour initiation, progression as well treatment resistance. In this study, markers CD 44, Bmi1, Oct4 Nanog was evaluated...
Abstract Background Tongue squamous cell carcinoma (SCC) contains a subpopulation referred to as cancer stem cells (CSCs), which are responsible for tumor growth, metastasis, and resistance chemotherapy radiotherapy. The CSC markers have been used isolate these biomarkers predict overall survival. Methods CD44, NANOG, OCT4, BMI1 were investigated using reverse transcriptase‐quantitative polymerase chain reaction (RT‐qPCR) immunohistochemistry correlated with clinicopathological parameters....
Full-thickness mucoperiosteal flap (FTF) elevation could potentially affect the periodontium of involved teeth; it is not clear if periodontal phenotype teeth in a FTF may influence these changes. The aim this study was to evaluate impact on periodontium, as well assessing bone remodeling.In single arm prospective clinical trial, 26 subjects and total 52 adjacent were included. Patients receiving implant surgery posterior area, at time site preparation, an extended one tooth mesial distal...
Background Hepatocellular carcinoma ( HCC ) is the most frequent type of liver cancer and its occurrence in oral cavity as a metastatic neoplasm rare event. We describe fatal case with metastasis patient firstly diagnosed prostatic hepatic carcinomas. The histopathological examination revealed hepatocyte‐like tumour cells arranged organoid structures well positivity to cytokeratin 8 Hep Par 1. present findings highlight importance complete medical evaluation identify possible repercussions...
Abstract Advanced salivary gland mucoepidermoid carcinoma (MEC) is a relentless cancer that exhibits resistance to conventional chemotherapy. As such, treatment for patients with advanced MEC tipically radical surgery and radiotherapy. Facial disfigurement poor quality of life are frequent challenges, many succumb loco-regional recurrence and/or metastasis. We know stem-like cells (CSC) drive tumorigenesis. The current study tests the hypothesis CSC sensitive therapeutic inhibition mTOR....
Introduction A disharmonious smile results from excessive gingival exposure or margin misalignment is a frequent finding in patients. The most common cause altered passive eruption; however, the case presented here, esthetics of compromised also due to an inadequate implant placement and crown fabrication. Case presentation This combination eruption buccally as well deeply placed (#10) that led disproportionate dimensions upper lateral incisor. Dual digitally guided lengthening surgical...
What are the fundamental debates and questions related to newly developed two-vector system for classification of periodontal diseases that have emerged as how accurately assign, stage, grade periodontitis cases? The aim present manuscript is demonstrate essential thought processes needed in utilizing new diagnose two gray zone cases.Clinical case 1 includes an 83-year-old male diagnosed with classified Stage III Generalized Grade B periodontitis, while clinical 2, a 73-year-old was...