Suzana Cantanhede Orsini Machado de Sousa

ORCID: 0000-0002-9708-9608
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Research Areas
  • Oral and Maxillofacial Pathology
  • Salivary Gland Tumors Diagnosis and Treatment
  • Bone Tumor Diagnosis and Treatments
  • Tumors and Oncological Cases
  • Soft tissue tumor case studies
  • Ear and Head Tumors
  • Sarcoma Diagnosis and Treatment
  • Vascular Malformations and Hemangiomas
  • Oral Health Pathology and Treatment
  • Head and Neck Cancer Studies
  • Oral and gingival health research
  • Cancer Diagnosis and Treatment
  • Cancer and Skin Lesions
  • Vascular Tumors and Angiosarcomas
  • Head and Neck Surgical Oncology
  • Salivary Gland Disorders and Functions
  • Head and Neck Anomalies
  • dental development and anomalies
  • Periodontal Regeneration and Treatments
  • Bone and Dental Protein Studies
  • Parvovirus B19 Infection Studies
  • Laser Applications in Dentistry and Medicine
  • Neurofibromatosis and Schwannoma Cases
  • Histiocytic Disorders and Treatments
  • Oral and Craniofacial Lesions

Universidade de São Paulo
2014-2024

Hospital Universitário da Universidade de São Paulo
2013-2022

National Council for Scientific and Technological Development
2015

Universidade Estadual do Amapá
2014

Universidade Federal da Bahia
2014

Abstract Low‐level laser therapy (LLLT) is a non‐thermal phototherapy used in several medical applications, including wound healing, reduction of pain and amelioration oral mucositis. Nevertheless, the effects LLLT upon cancer or dysplastic cells have been so far poorly studied. Head neck patients receiving for mucositis, example, might remaining tumor that could be stimulated by LLLT. This study demonstrated (GaAlAs – 660 nm 780 nm, 40 mW, 2.05, 3.07 6.15 J/cm 2 ) can modify (DOK) (SCC9...

10.1002/jbio.201300015 article EN Journal of Biophotonics 2013-04-02

To perform an oral biopsy survey focused on the incidence of lesions in Brazilian elderly patients.A total 17 329 records were analysed and divided into two age groups: patients, > or =60 years old; non-elderly <60 old. Information about sex, race, histopathological diagnosis (categorised non-neoplastic neoplastic lesions) was collected. Differences tested by comparison between proportions (binomial test).The epithelial malignant neoplasms pre-malignant group higher than group, as well...

10.1111/j.1741-2358.2006.00090.x article EN Gerodontology 2006-01-23

J Oral Pathol Med (2012) 41 : 272–280 Screening for expression of amelogenesis‐related proteins represents a powerful molecular approach to characterize odontogenic tumors and investigate their pathogenesis. In this study, we have examined the presence distribution ameloblast‐associated protein (ODAM), amelotin (AMTN), ameloblastin (AMBN), amelogenin (AMEL) by immunohistochemistry in samples adenomatoid tumor (AOT), calcifying epithelial (CEOT), developing odontoma, ameloblastoma, cystic...

10.1111/j.1600-0714.2011.01079.x article EN Journal of Oral Pathology and Medicine 2011-09-21

The purposes of this study were to assess clinical, histopathological and immunohistochemical features 22 oral neurofibromas (NFs) discuss with previously described literature, addressing the main aspects regarding differential diagnosis.Immunohistochemical reactions included S-100, CD34, GLUT-1, EMA, Ki-67, p53 Collagen IV histochemical for Alcian blue.Clinically, preferential location was maxillary bones, tongue buccal mucosa. Microscopically, widely spread spindle-shaped cells scant...

10.3109/00016357.2011.640286 article EN Acta Odontologica Scandinavica 2012-01-03

Background Mucoepidermoid carcinoma ( MEC ) is the most common salivary gland malignancy and successfully treated by surgery radiation. However, some patients have recurrent tumours in these cases, few treatments options are available. Cancer stem cells CSC been observed isolated from different solid based on expression of cell markers. These associated with tumour initiation, progression as well treatment resistance. In this study, markers CD 44, Bmi1, Oct4 Nanog was evaluated...

10.1111/jop.12449 article EN Journal of Oral Pathology and Medicine 2016-05-01

A hamartoma is a benign proliferation of typical mature cells specific to particular anatomical site. In the oral cavity, they may occur as isolated cases or be associated with genetic syndromes. Oral-facial-digital syndrome type VI rare disorder an estimated incidence one in 50,000-250,000 newborns. Here, we report case 2-year-old boy diagnosed oral-facial-digital who was referred for evaluation bilateral and normochromic slightly pinkish nodule on lateral surface tongue. Clinically, child...

10.1111/scd.12958 article EN Special Care in Dentistry 2024-01-07

It is still controversial whether human papillomavirus (HPV) can be considered a risk factor in oral carcinogenesis. The aim of this study was to detect HPV DNA 50 cases diagnosed as leukoplakias, with different degrees epithelial dysplasia, and squamous cell carcinomas, using situ hybridization signal amplification (CSA-ISH).HPV assessed paraffin sections CSA-ISH wide-spectrum biotinylated probe. In HPV-positive cases, genotyping specific probes types 6/11, 16/18 31/33 performed.The overall...

10.1111/j.1399-302x.2007.00422.x article EN Oral Microbiology and Immunology 2008-06-11

The aim of this study was to evaluate the effects injection two phlogistic agents, carrageenan and formalin, in rat TMJ, inflammatory process induced by these substances. In study, a total 45 adult rats were distributed experimental groups control group. animals sacrificed after three hours, 24 days, seven 15 days single each substance. Histological data initially demonstrated an represented acute infiltration, which later became mixed, finally chronic both groups. Hyperplasia synovial...

10.1590/s1806-83242005000200005 article EN cc-by Brazilian Oral Research 2005-06-01

Objective To evaluate the efficacy of M elaleuca alternifolia and C opaifera officinalis in inhibiting adhesion andida albicans biofilm. Background Over 65% denture wearers suffer from stomatitis, which is one most prevalent forms oral candidiasis. This disease characterised by inflammation mucosa contact with contaminated denture. The contributes to switch . yeast its pathogenic hyphal form. adheres colonises polymethylmethacrylate resin surfaces thus development stomatitis. Materials...

10.1111/ger.12172 article EN Gerodontology 2014-12-01

Background Although not rare, vascular lesions occurring in the lips sometimes poses a difficult properly diagnosing and handling them. In this study, were retrieved from an Oral Pathology Service. Methods Among 5600 biopsies, 131 cases found. The following diagnoses attributed: caliber‐persistent artery, infantile hemangioma, malformation, venous lake, thrombus, papillary endothelial hyperplasia pyogenic granuloma. Clinical data obtained patients’ records. Results lesions’ frequency were:...

10.1111/cup.12911 article EN Journal of Cutaneous Pathology 2017-01-23

Oral melanoacanthoma (OMA) is a rare benign lesion characterized by colonization of acanthotic epithelium dendritic melanocytes. Although its pathogenenesis remains uncertain, clinical behavior and spontaneous remission suggest non-neoplastic nature. Clinically, it may present as solitary or multifocal lesion; however these two variants exhibit different features. The appearance OMA not pathognomonic biopsy mandatory. requires no treatment periodic observation. Here, we report case with...

10.2334/josnusd.51.463 article EN Journal of Oral Science 2009-01-01

Marques Y M F S, Giudice Freitas V M, Abreu e Lima d C C, Hunter K D, Speight P &amp; Machado de Sousa S O (2012) Histopathology 60, 609–616 Oestrogen receptor β in adenoid cystic carcinoma of salivary glands Aims: This study aimed to describe the expression oestrogen (ER)α, ERβ and aromatase gland (ACC). Methods results: ERα, was analysed by immunohistochemistry tissue microarray blocks from 38 cases ACC seven normal glands. The intracellular localization amount total protein were...

10.1111/j.1365-2559.2011.04095.x article EN Histopathology 2012-01-19

Canalicular adenoma (CA) is an uncommon benign salivary gland tumor that mostly occurs in the upper lip. Despite its nature, some patients may present multiple nodules and also microscopic growth can be multifocal with foci of within adjacent gland. Microscopically, CA mistaken for a polymorphous low-grade adenocarcinoma (PLGA) or basal cell (BCA), immunohistochemistry helpful differentiating them. Two cases canalicular showing are described. Both occurred lip white females aged 72 79 years....

10.1590/0103-6440201302264 article EN cc-by Brazilian Dental Journal 2013-10-01
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