A5023340002- Oral and gingival health research
- Oral and Maxillofacial Pathology
- Oral Health Pathology and Treatment
- HIV/AIDS oral health manifestations
- Tumors and Oncological Cases
- Cancer Diagnosis and Treatment
- Oral health in cancer treatment
- Viral-associated cancers and disorders
- T-cell and Retrovirus Studies
- Hedgehog Signaling Pathway Studies
- dental development and anomalies
- Ocular Disorders and Treatments
- Body Contouring and Surgery
- Bone health and treatments
- PI3K/AKT/mTOR signaling in cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Noise Effects and Management
- Oral and Craniofacial Lesions
- Colorectal Cancer Surgical Treatments
- Cleft Lip and Palate Research
- Hearing, Cochlea, Tinnitus, Genetics
- Autoimmune Bullous Skin Diseases
- Histiocytic Disorders and Treatments
- Bariatric Surgery and Outcomes
- Hearing Loss and Rehabilitation
Universidade de São Paulo
2013-2024
Universidade de Santo Amaro
2017-2024
Pontifícia Universidade Católica do Paraná
2021
Faculdades Oswaldo Cruz
2020
Johnson & Johnson (Brazil)
2015-2019
Ghent University Hospital
2017
Secretaria Municipal de Saúde
2015
Fundação Faculdade de Odontologia
2011-2014
Universidade Estadual Paulista (Unesp)
2014
Hospital of St. Francis Xavier
2013
Abstract The objective of this study was to estimate the prevalence comorbidities among people living with HIV/AIDS (PLWHIV) attending a dental outpatient clinic and discuss impact these on management. A cross-sectional observational evaluated 238 PLWHIV specialized in Brazil. We collected sociodemographic data, self-reported physician-diagnosed comorbidities, hemogram results, CD4+ T cell count, viral load, use combined antiretroviral therapy (cART), information harmful habits. most...
PI3K-AKT-mTOR signaling pathway is associated with several cellular functions and frequently changed in malignancies. The aim of this study was to characterize the immunohistochemical expression pattern components oral epithelial dysplasia (OED), comparing squamous cell carcinoma (OSCC) non-dysplastic tissues (NDOT).A total 186 cases NDOT, OED OSCC were retrieved. Nuclear staining cytoplasmic keratinocytes considered positive, percentage positive cells calculated.Increased immunoreactivity...
Oral manifestations are common findings in human immunodeficiency virus (HIV) infected patients and frequently influence the overall health. hairy leukoplakia (OHL) is strongly associated with HIV infection demonstrating its relationship individual's immune status progression of immunosuppression. This study aims to retrospectively evaluate OHL patients, analyzing incidence, demographic aspects possible changes clinical epidemiological profile disease over 17 years. The records 1600...
Neuropilins are receptors for disparate ligands, including proangiogenic factors such as vascular endothelial growth factor and inhibitory class 3 semaphorin (SEMA3) family members. Differentiated cells in skin epithelium cutaneous squamous cell carcinoma highly express the neuropilin-1 (NRP1) receptor. We examined expression of NRP1 human mouse oral mucosa. was significantly up-regulated epithelial dysplasia (OSCC). receptor localized to outer suprabasal layers normal tongue, an pattern...
Human T-cell lymphotropic virus type 1 (HTLV-1) was the first human retrovirus discovered and its pathogenesis is related to T cells infection. This study aimed verify presence of oral manifestations in a Brazilian population patients who seropositive for HTLV, identify risk factors manifestations.An assessment made 139 at Emilio Ribas Institute Infectious Diseases.A total 112 (80.5%) were HTLV-1, 26 (18.7%) HTLV-2+. About 35.2% had myelopathy/tropical spastic paraparesis (HAM/TSP), with 48...
Dental management of patients with epi-dermolysis bullosa (EB) is challenging because the severe soft tissue lesions associated this disease. A case history presented where two immediate endosseous implants were placed in mandible a patient recessive dystrophic EB using computer-aided technology to plan surgery and prosthetic rehabilitation. After 24-month follow-up, prosthesis was stable healthy asymptomatic around implants. The stereolithographic model provides precise noninvasive copy...
The literature indicates that neonatal hearing screening should be universal, so a description of programs adopt this recommendation is relevant.To describe the results newborn and profile mothers newborns attended to in low-risk maternity setting, correlate characteristics population with transient evoked otoacoustic emissions.A contemporary cross-sectional cohort study. sample consisted 670 infants procedures performed were audiological history, transient-evoked emissions (TEOAE),...
Plasmablastic lymphoma (PBL) is an HIV-associated non-Hodgkin's that primarily affects the oral cavity. We describe case of HIV patient with a lesion in maxilla lasted four months. He was diagnosed PBL and received highly active antiretroviral therapy as well chemotherapy local radiotherapy. The regressed after third cycle chemotherapy. interrupted treatment recurred. immune reconstitution secondary to use seems participate regression maintains remission tumour, but it might not be enough...
A previously unreported case of Barber-Say syndrome is described with special attention to dental manifestations. 7-year-old female multiple congenital anomalies such mammary gland hypoplasia, hypertrichosis, ectropion, and redundant skin was seen at the School Dentistry University São Paulo. Oral examination revealed macrostomia, broad alveolar ridges, gingival fibromatosis, taurodontism, delayed tooth eruption, malocclusion. Dental treatment included gingivoplasty orthodontic treatment.
Background: Drug-induced gingival overgrowth (DIGO) is attributed mainly to the prolonged use of calcium channel blocking agents, anticonvulsants, and anti-calcineurin inhibitors . The management DIGO depends on severity disease includes surgical intervention plaque control. Compared conventional treatment, recent literature data have shown that gingivectomy using a high-power laser (HPL) short easy procedure, which results in minimal postoperative discomfort greater patient accep- tance....
Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation painful black and red located on the right aspect oropharyngeal isthmus. After incisional biopsy, resulting sample was situ, diagnosis further confirmed by immunohistochemical analysis. Treatment consisted total excision...
Barber-Say syndrome (BSS) and ablepharon-macrostomia (AMS) are infrequently reported congenital malformation disorders caused by mutations in the TWIST2 gene. Both characterized abnormalities ectoderm-derived structures cause a very unusual morphology of mainly face individuals with otherwise normal cognition physical functioning. We studied impact that presence BSS AMS has on psychosocial functioning affected their families, using point view to start with. tabulated frequently asked...
Oral inverted ductal papilloma (OIDP) is a rare, nonrecurrent,benign lesion of salivary glands. The etiologyis still poorly understood; the correlation with humanpapilloma virus (HPV) controversial. Herein wepresent 74-year-old man tumor in lower lip.Incisional biopsy was performed and histologicaldiagnosis OIDP. Inno-LiPA assay, based onpolymerase chain reaction situ hybridizationwas used to assess for HPV no detection viralDNA. Surgical excision without anyrecurrences after two years follow-up.