A5028274750- Oral health in cancer treatment
- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Oral Health Pathology and Treatment
- Oral and gingival health research
- Hematopoietic Stem Cell Transplantation
- Effects of Radiation Exposure
- Neutropenia and Cancer Infections
- Oral microbiology and periodontitis research
- Colorectal Cancer Treatments and Studies
- Salivary Gland Disorders and Functions
- Cancer Treatment and Pharmacology
- Laser Applications in Dentistry and Medicine
- Cancer Immunotherapy and Biomarkers
- Bioinformatics and Genomic Networks
- Gene expression and cancer classification
- Immune Response and Inflammation
- Head and Neck Surgical Oncology
- Immunotherapy and Immune Responses
- Lung Cancer Research Studies
- Chemotherapy-related skin toxicity
- Dental Education, Practice, Research
- Polyomavirus and related diseases
- Cancer Research and Treatments
- Periodontal Regeneration and Treatments
Dana-Farber Brigham Cancer Center
2016-2025
Brigham and Women's Hospital
2016-2025
Dana-Farber Cancer Institute
2016-2025
Harvard University
2016-2025
Institute of Infection and Immunity
2004-2022
Clinical Solutions
2022
Harvard University Press
2003-2020
University of Massachusetts Lowell
2019
Dana-Farber/Harvard Cancer Center
2008-2017
University of Genoa
2016
BACKGROUND Mucositis is a highly significant, and sometimes dose‐limiting, toxicity of cancer therapy. The goal this systematic review was to update the Multinational Association Supportive Care in Cancer International Society Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for mucositis. METHODS A literature search conducted identify eligible published articles, based on predefined inclusion/exclusion criteria. Each article independently reviewed by 2 reviewers. Studies were rated...
BACKGROUND Oral and gastrointestinal (GI) mucositis can affect up to 100% of patients undergoing high-dose chemotherapy hematopoietic stem cell transplantation, 80% with malignancies the head neck receiving radiotherapy, a wide range chemotherapy. Alimentary track increases mortality morbidity contributes rising health care costs. Consequently, Multinational Association Supportive Care in Cancer International Society for Oncology assembled an expert panel evaluate literature create...
Considerable progress in research and clinical application has been made since the original guidelines for managing mucositis cancer patients were published 2004, first active drug prevention treatment of this condition approved by United States Food Drug Administration other regulatory agencies Europe Australia. These changes necessitate an updated review literature guidelines. Panel members reviewed biomedical on English between January 2002 May 2005 reached a consensus based criteria...
PURPOSE: To explore the relationship between oral mucositis and selected clinical economic outcomes in blood marrow transplant patients. PATIENTS AND METHODS: Subjects consisted of 92 patients from eight centers who participated a multinational pilot study new scoring system (Oral Mucositis Assessment Scale [OMAS]). In study, were evaluated for erythema ulceration/pseudomembrane formation beginning on first day conditioning continuing 28 days. We examined patients’ peak OMAS scores days with...
BACKGROUND An impediment to mucositis research has been the lack of an accepted, validated scoring system. The objective this study was design, test, and validate a new system for that can be used easily, is reproducible, provides accurate applications. METHODS A panel experts, convened design objective, simple, reproducible assessment tool evaluate with specific application multicenter clinical trials, developed scale measured subjective indicators mucositis. Nine centers participated in...
Abstract BACKGROUND The current study was conducted to characterize the risks and clinical consequences of oral mucositis (OM) in patients with head neck carcinoma (HNC) who are receiving radiation therapy. METHODS Data regarding 450 HNC had received therapy were collected via chart review from 154 U.S. medical oncologists. Information obtained included patient characteristics, treatments received, highest recorded grade OM during (none, mild, moderate, or severe), outcomes potentially...
Abstract BACKGROUND. The risk, severity, and patient‐reported outcomes of radiation‐induced mucositis among head neck cancer patients were prospectively estimated. METHODS. A validated, questionnaire (OMDQ), the FACT quality life (QOL), Functional Assessment Chronic Illness Therapy (FACIT) fatigue scales used to measure (reported as mouth throat soreness), daily functioning, use analgesics. Patients studied before radiotherapy (RT), during RT, for 4 weeks after RT. RESULTS. Contrary previous...
Background. Few longitudinal studies have investigated the onset, duration, and resolution of ulcerative mucositis in bone marrow transplant recipients. This study prospectively followed a group such patients on daily basis to obtain data incidence mucositis, location duration lesions, severity with different conditioning regimens, relationship absolute neutrophil count. Methods. Fifty-nine recipients prophylactic acyclovir were examined for 26 days after infusion, all oral lesions recorded....