- Oral Health Pathology and Treatment
- Oral and Maxillofacial Pathology
- Oral and gingival health research
- Cancer Diagnosis and Treatment
- Bone health and treatments
- Tumors and Oncological Cases
- Oral health in cancer treatment
- Head and Neck Cancer Studies
- Bone and Joint Diseases
- Cancer and Skin Lesions
- Salivary Gland Tumors Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Autoimmune Bullous Skin Diseases
- Bone Tumor Diagnosis and Treatments
- Salivary Gland Disorders and Functions
- Autoimmune and Inflammatory Disorders
- Immunodeficiency and Autoimmune Disorders
- Head and Neck Surgical Oncology
- Genetic and rare skin diseases.
- Soft tissue tumor case studies
- Cancer Immunotherapy and Biomarkers
- Ear and Head Tumors
- Dermatologic Treatments and Research
- Viral-associated cancers and disorders
- Cutaneous Melanoma Detection and Management
Harvard University
2016-2025
Brigham and Women's Hospital
2016-2025
Dana-Farber Cancer Institute
1990-2025
Dana-Farber Brigham Cancer Center
2006-2025
King's College London
2023
St John's Hospital
2023
Guy's and St Thomas' NHS Foundation Trust
2023
Guy's Hospital
2023
Massachusetts General Hospital
2013-2021
American Society for Bone and Mineral Research
2020
Background. Few longitudinal studies have investigated the onset, duration, and resolution of ulcerative mucositis in bone marrow transplant recipients. This study prospectively followed a group such patients on daily basis to obtain data incidence mucositis, location duration lesions, severity with different conditioning regimens, relationship absolute neutrophil count. Methods. Fifty-nine recipients prophylactic acyclovir were examined for 26 days after infusion, all oral lesions recorded....
Abstract Purpose. Potentially debilitating, osteonecrosis of the jaw (ONJ) is an emerging complication bisphosphonates. However, its effect on quality life (QoL) unknown. We determined ONJ-related QoL decline in a cancer patient cohort. Patients and Methods. Thirty-four patients with bisphosphonate-associated ONJ completed telephone survey (October 2007 through May 2008). The Oral Health Impact Profile 14 (OHIP) retrospectively assessed participant oral health–related before after ONJ....
Proliferative verrucous leukoplakia (PVL) is an aggressive oral precancerous disease characterized by a high risk of transformation to invasive squamous cell carcinoma (OSCC), and no therapies have been shown affect its natural history. A recent study the PVL immune landscape revealed cytotoxic T-cell-rich microenvironment, providing strong rationale investigate checkpoint therapy.
No consensus has yet been reached to associate oral bacteria conclusively with the etio-pathogenesis of bisphosphonate-induced osteonecrosis jaw (BONJ). Therefore, present study examined effects on development BONJ-like lesions in a mouse model. In pamidronate (Pam)-treated mice, but not control non-drug-treated tooth extraction followed by infection Fusobacterium nucleatum caused and delayed epithelial healing, both which were completely suppressed broad-spectrum antibiotic cocktail....
Oral potentially malignant disorders (OPMDs) include a variety of lesions and conditions characterized by an increased risk for transformation (MT) to oral squamous cell carcinoma (OSCC) [1]. Leukoplakia erythroplakia are the most common OPMDs, while special emphasis has been placed on premalignant nature lichen planus (OLP) [2]. It is generally accepted that histopathological features given lesion, especially presence degree epithelial dysplasia, currently useful indicators MT [3]....
Abstract Head and neck cancers are a complex malignancy comprising multiple anatomical sites, with cancer of the oral cavity ranking among deadliest most disfiguring globally. Oral (OC) constitutes subset head cases, presenting primarily as tobacco- alcohol-associated squamous cell carcinoma (OSCC), 5-year survival rate ~ 65%, partly due to lack early detection effective treatments. OSCC arises from premalignant lesions (PMLs) in through multi-step series clinical histopathological stages,...