A5072215036- Oral health in cancer treatment
- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Oral Health Pathology and Treatment
- Oral and gingival health research
- Oral microbiology and periodontitis research
- Neutropenia and Cancer Infections
- Salivary Gland Disorders and Functions
- Chemotherapy-related skin toxicity
- Bone health and treatments
- HIV/AIDS oral health manifestations
- Colorectal Cancer Treatments and Studies
- Oral and Maxillofacial Pathology
- Antifungal resistance and susceptibility
- Salivary Gland Tumors Diagnosis and Treatment
- Bone and Joint Diseases
- Hematological disorders and diagnostics
- Hematopoietic Stem Cell Transplantation
- Head and Neck Surgical Oncology
- Cancer Treatment and Pharmacology
- Clinical practice guidelines implementation
- Dental Education, Practice, Research
- Lung Cancer Research Studies
- Inflammatory mediators and NSAID effects
- Cancer survivorship and care
UConn Health
2014-2025
University of Connecticut
2002-2024
Samsung (United States)
2022
Pfizer (United States)
2022
NOSM University
2020
Sheba Medical Center
2020
Tel Aviv University
2020
Health Sciences North
2020
American Society of Clinical Oncology
2020
University of Pittsburgh
2017
BACKGROUND Mucositis is a highly significant, and sometimes dose‐limiting, toxicity of cancer therapy. The goal this systematic review was to update the Multinational Association Supportive Care in Cancer International Society Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for mucositis. METHODS A literature search conducted identify eligible published articles, based on predefined inclusion/exclusion criteria. Each article independently reviewed by 2 reviewers. Studies were rated...
BACKGROUND Oral and gastrointestinal (GI) mucositis can affect up to 100% of patients undergoing high-dose chemotherapy hematopoietic stem cell transplantation, 80% with malignancies the head neck receiving radiotherapy, a wide range chemotherapy. Alimentary track increases mortality morbidity contributes rising health care costs. Consequently, Multinational Association Supportive Care in Cancer International Society for Oncology assembled an expert panel evaluate literature create...
Considerable progress in research and clinical application has been made since the original guidelines for managing mucositis cancer patients were published 2004, first active drug prevention treatment of this condition approved by United States Food Drug Administration other regulatory agencies Europe Australia. These changes necessitate an updated review literature guidelines. Panel members reviewed biomedical on English between January 2002 May 2005 reached a consensus based criteria...
PURPOSE: To explore the relationship between oral mucositis and selected clinical economic outcomes in blood marrow transplant patients. PATIENTS AND METHODS: Subjects consisted of 92 patients from eight centers who participated a multinational pilot study new scoring system (Oral Mucositis Assessment Scale [OMAS]). In study, were evaluated for erythema ulceration/pseudomembrane formation beginning on first day conditioning continuing 28 days. We examined patients’ peak OMAS scores days with...
The current report presented 17 patients with cancer bone metastases and 1 patient osteopenia who received treatment bisphosphonates subsequently developed osteonecrosis of the mandible and/or maxilla.The authors reviewed information on 18 were referred to oral medicine or surgery specialists for evaluation mandibular maxillary necrosis from June 2002 September 2004. To be included in review, must have been treated either pamidronate zoledronic acid control prevent metastatic disease,...
BACKGROUND An impediment to mucositis research has been the lack of an accepted, validated scoring system. The objective this study was design, test, and validate a new system for that can be used easily, is reproducible, provides accurate applications. METHODS A panel experts, convened design objective, simple, reproducible assessment tool evaluate with specific application multicenter clinical trials, developed scale measured subjective indicators mucositis. Nine centers participated in...
Gastrointestinal mucosal injury (mucositis), commonly affecting the oral cavity, is a clinically significant yet incompletely understood complication of cancer chemotherapy. Although antineoplastic cytotoxicity constitutes primary trigger, interaction microbial commensals with tissues could modify response. It not clear, however, whether chemotherapy and its associated treatments affect communities disrupting homeostatic balance between resident microorganisms adjacent mucosa if such...
ASCO Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following guideline development process as outlined in Methodology Manual . follow Conflict Interest Policy Clinical Practice other guidance (“Guidance”) provided by is not a or definitive guide to treatment options. It intended voluntary use providers should be used conjunction independent professional judgment. Guidance may applicable all patients,...
Summary High throughput sequencing of 16S ribosomal RNA gene amplicons is a cost‐effective method for characterization oral bacterial communities. However, before undertaking large‐scale studies, it necessary to understand the technique‐associated limitations and intrinsic variability ecosystem. In this work we evaluated bias in species representation using an vitro ‐assembled mock community bacteria. We then characterized communities saliva buccal mucosa five healthy subjects investigate...
PURPOSE To provide evidence-based recommendations for prevention and management of salivary gland hypofunction xerostomia induced by nonsurgical cancer therapies. METHODS Multinational Association Supportive Care in Cancer/International Society Oral Oncology (MASCC/ISOO) ASCO convened a multidisciplinary Expert Panel to evaluate the evidence formulate recommendations. PubMed, EMBASE, Cochrane Library were searched randomized controlled trials published between January 2009 June 2020. The...
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