A5006038962- Glioma Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Effects of Radiation Exposure
- Head and Neck Cancer Studies
- Radiation Detection and Scintillator Technologies
- Head and Neck Surgical Oncology
- Sarcoma Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Oral health in cancer treatment
- Atrial Fibrillation Management and Outcomes
- MRI in cancer diagnosis
- CNS Lymphoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Endometrial and Cervical Cancer Treatments
- Cancer, Hypoxia, and Metabolism
- Advanced X-ray and CT Imaging
- Dental Implant Techniques and Outcomes
- Neurological and metabolic disorders
- Uterine Myomas and Treatments
- Brain Metastases and Treatment
- Digital Imaging in Medicine
- Neuroinflammation and Neurodegeneration Mechanisms
- Colorectal and Anal Carcinomas
Centre François Baclesse
2019-2025
Laboratoire de Physique Corpusculaire de Caen
2022-2025
École Nationale Supérieure d'Ingénieurs de Caen
2022-2025
Normandie Université
2025
Centre François Baclesse
2020-2024
Université de Caen Normandie
2024
Centre National de la Recherche Scientifique
2024
Université Côte d'Azur
2023
Centre de Biologie du Développement
2023
Centre Antoine Lacassagne
2019
ABSTRACT Purpose Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy (RT) to head and neck. With over 9 published definitions at least 16 diagnostic/staging systems, true incidence severity ORNJ are obscured lack standard for definition assessment, leading inaccurate estimation incidence, reporting ambiguity, likely under-diagnosis worldwide. This study aimed achieve consensus on an explicit phenotype related precursor...
Although lymphopenia is linked to immune suppression favoring tumor growth, the effect of different radiation types on specific T-lymphocyte subsets remains unclear. Among subpopulations, CD8+-lymphocytes serve as key effectors in cancer immunity. This study aimed examine changes subpopulations both tumor-free and glioblastoma-bearing mice following brain-irradiation. The was divided into two main phases. First, C57BL/6 mice, with or without glioblastoma (GL261 cells), received hemispheric...
Radiation-induced sarcoma (RIS) is a rare but serious event. Its occurrence has been discussed during the implementation of new radiation techniques and justified appropriate radioprotection requirements. New approaches targeting intrinsic radio-sensitivity have described, such as radiation-induced CD8 T-lymphocyte apoptosis (RILA) able to predict late radio-induced toxicities. We studied role RILA predisposing factor for RIS adverse event following therapy (RT).In this prospective...
Up to 50% of soft tissue sarcoma (STS) patients develop metastases in the course their disease. Cytotoxic therapy is a standard treatment this setting but yields average tumour response rates 25% at first line and ≤10% later lines. In oligometastatic stage, stereotactic body radiation (SBRT) allows reaching high control treated sites (≥80%) potentially equally effective surgery term overall survival. order shift balance towards antitumour immunity by multisite irradiation, could be combined...
Abstract In this work, we developed a three-dimensional (3D) scintillation system, whose fast response and high sensitivity allow the measurement of pencil beam (PB) characteristics (position, energy intensity in terms monitor units - MU) for scanning proton therapy. The system consists 10 × cm 3 scintillator cube that produces visible light when irradiated with PBs. A high-speed camera records distribution mirror positioned at 45° to allows visualization two orthogonal faces cube....