- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Medical Imaging Techniques and Applications
- Oral health in cancer treatment
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Effects of Radiation Exposure
- Dysphagia Assessment and Management
- Radiation Therapy and Dosimetry
- Cardiac pacing and defibrillation studies
- Radiation Dose and Imaging
- Oral and Maxillofacial Pathology
- Neurobiology and Insect Physiology Research
- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- Advanced MRI Techniques and Applications
- Lung Cancer Research Studies
- Brain Metastases and Treatment
- Nutrition and Health in Aging
- Sinusitis and nasal conditions
Odense University Hospital
2016-2025
Aarhus University Hospital
1994-2024
University of Southern Denmark
2012-2024
University of Copenhagen
1981-2023
Gentofte Hospital
2016-2023
University Hospital of Lausanne
2021
Copenhagen University Hospital
2006-2021
Herlev Hospital
2009-2021
Medical Cañada (Spain)
2020
Hopital Universitaire Habib Bourguiba
2019
PurposeHypoxia is a cause of resistance to radiotherapy, especially in patients with head and neck squamous cell carcinoma (HNSCC). The purpose this study was evaluate 18F-fluoroazomycin arabinoside (FAZA) positron emission tomography (PET)/computed (CT) hypoxia imaging as prognostic factor HNSCC receiving radiotherapy.Material methodsForty treated radiotherapy (66–76 Gy) were included. Static FAZA PET/CT 2 h post injection conducted prior irradiation. hypoxic volume (HV) delineated using...
Because of the unprecedented disruption health care services caused by COVID-19 pandemic, American Society Radiation Oncology (ASTRO) and European for Radiotherapy (ESTRO) identified an urgent need to issue practice recommendations radiation oncologists treating head neck cancer (HNC) in a time limited resources heightened risk patients staff.
Background: The project aimed at determining the incidence of mandibular osteoradionecrosis (ORN) after radiotherapy, possible risk factors, and dose-volume effects in a large cohort head neck cancer patients (HNC).Methods: consisted 1224 HNC treated with 66–68 Gy 2007–2015 predominantly IMRT. ORN cases were defined from clinical observations follow-up through hospital code diagnostics oral-maxillofacial surgery cross-checked national Danish Head Neck Cancer database. In nested case–control...
The distribution and morphology of glutamatergic synapses on Drosophila bodywall muscle fibers were examined at the single-synapse level using immunocytochemistry electrophysiology. We find that glutamate-immunoreactive motor endings innervate entire larval musculature, with each fiber receiving least one ending. innervation is initiated stereotyped locations from where moderately branched varicose nerve processes project over internally facing surface. Individual have distinct stereotypic...
Different factors predict nodal metastasis, recurrence and survival in oral cancer. The aim was to assess the prognostic value of histological features related primary tumour.A total 144 patients surgically treated at Odense University Hospital for cancer between 1999 2004 were included study. Postoperative radiation therapy given case close involved margins or high TNM stages (UICC 1997). Median follow-up time 38 months. All surgical resections reviewed 22 characteristics assessed.The...
Abstract Background. The benefit of a complementary fluorodeoxyglucose‐positron emission tomography (FDG‐PET) scan to standard workup for carcinoma unknown primary (CUP) and metastatic neck lesions was prospectively studied. Methods. Sixty‐seven patients underwent standardized diagnostic according national guidelines including panendoscopies, multiple mucosal biopsies, CT/MRI scans. Median follow‐up 40 months (range, 2–65 months). Results. In 60 eligible patients, FDG‐PET indicated tumor or...
HPV is found in head and neck cancer from all sites with a higher prevalence oropharynx (OPC) compared to non-OPC. HPV/p16-status has significant impact on radiotherapy (RT) outcome advanced OPC, but less known about the influence We analyzed HPV-associated p16-expression cohort of patients stage III-IV pharynx larynx treated primary, curatively intended (chemo-)RT, aiming test hypothesis that HPV/p16 also extends tumors non-oropharyngeal origin.1294 enrolled previously conducted...
Treatment planning is time‐consuming and the outcome depends on person performing optimization. A system that automates treatment could potentially reduce manual time required for optimization also provide a method to variation between persons radiation dose (dosimetrist) improve overall plan quality. This study evaluates performance of Auto‐Planning module has recently become clinically available in Pinnacle 3 therapy system. Twenty‐six delivered head neck plans were reoptimized with...