A5072625445- Reconstructive Surgery and Microvascular Techniques
- Body Contouring and Surgery
- Head and Neck Cancer Studies
- Breast Implant and Reconstruction
- Lymphatic System and Diseases
- Wound Healing and Treatments
- Pressure Ulcer Prevention and Management
- Salivary Gland Tumors Diagnosis and Treatment
- Diagnosis and Treatment of Venous Diseases
- Cancer Diagnosis and Treatment
- Mesenchymal stem cell research
- Surgical site infection prevention
- Advancements in Transdermal Drug Delivery
- Diabetic Foot Ulcer Assessment and Management
- Tissue Engineering and Regenerative Medicine
- Medical Imaging Techniques and Applications
- Head and Neck Surgical Oncology
- Bariatric Surgery and Outcomes
- Body Image and Dysmorphia Studies
- Reconstructive Facial Surgery Techniques
- Breast Cancer Treatment Studies
- Ear and Head Tumors
- Electrospun Nanofibers in Biomedical Applications
- Radiomics and Machine Learning in Medical Imaging
- Global Cancer Incidence and Screening
Odense University Hospital
2016-2025
University of Southern Denmark
2016-2025
Uppsala University
2011-2024
Center For Reconstructive Urethral Surgery
2024
Rigshospitalet
2022
Region of Southern Denmark
2020-2022
Odense Municipality
2022
Kongsberg Innovasjon (Norway)
2016-2020
Uppsala University Hospital
2004-2020
Mount Sinai Health System
2018
Cardiac amyloidosis is a differential diagnosis in heart failure and associated with high mortality. There currently no noninvasive imaging test available for specific diagnosis. <i>N-</i>[<i>methyl-</i><sup>11</sup>C]2-(4′-methylamino-phenyl)-6-hydroxybenzothiazole (<sup>11</sup>C-PIB) PET used the evaluation of brain amyloidosis. We evaluated potential use <sup>11</sup>C-PIB systemic affecting heart. <b>Methods:</b> Patients (<i>n</i> = 10) diagnosed amyloidosis—including involvement...
Abstract Wound microenvironment plays a major role in the process of wound healing. It contains various external and internal factors that participate pathophysiology. The pH is an important factor influences healing by changing throughout process. Several previous studies have investigated relation to pathogens but concentrating on effects itself are inconclusive. purpose this study was comprehensively controlled fashion investigate effect studying its human primary keratinocyte fibroblast...
Different factors predict nodal metastasis, recurrence and survival in oral cancer. The aim was to assess the prognostic value of histological features related primary tumour.A total 144 patients surgically treated at Odense University Hospital for cancer between 1999 2004 were included study. Postoperative radiation therapy given case close involved margins or high TNM stages (UICC 1997). Median follow-up time 38 months. All surgical resections reviewed 22 characteristics assessed.The...
Background MicroRNA (miRNA) expression is broadly altered in cancer, but few studies have investigated miRNA deregulation oral squamous cell carcinoma (OSCC). Epigenetic mechanisms are involved the regulation of >30 genes a range tissues, and we aimed to investigate this further OSCC. Methods TaqMan® qRT-PCR arrays individual assays were used profile panel 25 tumors with matched adjacent tissues from patients OSCC, 8 control paired stroma epithelium healthy volunteers. Associated DNA...
Abstract Background The aim was to estimate long-term mortality benefits and cost-effectiveness of screening for abdominal aortic aneurysm (AAA) in men aged 64–73 years. Methods All years living Viborg County were randomized be controls (n = 6306) or invited ultrasonography at a regional hospital 6333). Mortality AAA-related interventions recorded national databases. cost initial based on actual costs the programme. Incremental ratios (ICERs) calculated gains life Quality Adjusted Life Years...
A critical barrier to outcome assessment in gender-affirming healthcare is the lack of a specific patient-reported measure (PROM). This phase I protocol describes an international collaboration between investigators Canada, Denmark, Netherlands and USA who have coalesced develop new PROM (ie, GENDER-Q) evaluate outcomes psychological, hormonal surgical treatments.This study uses interpretive description approach. Participants aged 16 years older seeking any form treatments centres located...
To evaluate the reduction of surgical site infections by prophylactic incisional negative pressure wound therapy compared with standard postoperative dressings in obese women giving birth caesarean section.
Abstract The impact of breast cancer-related lymphedema (BCRL) on long-term quality life is unknown. aim this study was to investigate the BCRL health-related (HRQoL) up 10 years after cancer treatment. This regional population-based enrolled patients treated for with axillary lymph node dissection between January 1st 2007 and December 31th 2017. Follow assessments included were conducted 2019 May 2020. outcome HRQoL, evaluated Lymphedema Functioning, Disability Health Questionnaire,...
Involvement of the cervical lymph nodes is most important prognostic factor for patients with oral/oropharyngeal squamous cell carcinoma (OSCC), and decision whether to electively treat clinically negative necks remains a controversial topic. Sentinel node biopsy (SNB) provides minimally invasive method determining disease status basin, without need formal neck dissection. This technique potentially improves accuracy histologic nodal staging avoids overtreating three-quarters this patient...
Clinical PET of apoptosis may have substantial value in advancing patient care. We report here the first-in-humans study with <sup>18</sup>F-labeled 2-(5-fluoropentyl)-2-methyl malonic acid (<sup>18</sup>F-ML-10), a small-molecule tracer for apoptosis. Presented are dosimetry, biodistribution, stability, and safety profiles this healthy human volunteers. Also reported is binding to targeted apoptotic cells testicular tissue, where relative abundance normally observed....
Psoriasis and obesity are strongly linked, weight loss appears to improve psoriasis symptoms severity. Bariatric surgery may induce remission of psoriasis, but data limited small studies case series.To examine the incidence prognosis psoriatic arthritis in patients undergoing bariatric (gastric bypass gastric banding).This population-based cohort study used individual-level linkage administrative public health registers Denmark. All Danish citizens who received or banding between January 1,...
The purpose of this study was to determine the detection rate distant metastasis and synchronous cancer, comparing clinically used imaging strategies based on chest x-ray + head neck MRI (CXR/MRI) CT (CHCT/MRI) with <sup>18</sup>F-FDG PET/CT upfront in diagnostic workup patients oral, pharyngeal, or laryngeal cancer. <b>Methods:</b> This a prospective cohort paired data. Consecutive histologically verified primary squamous cell carcinoma at Odense University Hospital from September 2013...