- Oral and Maxillofacial Pathology
- Salivary Gland Tumors Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Oral and gingival health research
- Cancer Diagnosis and Treatment
- Bone health and treatments
- Ear and Head Tumors
- Tumors and Oncological Cases
- Bone and Joint Diseases
- Periodontal Regeneration and Treatments
- Dental Implant Techniques and Outcomes
- Facial Trauma and Fracture Management
- Dental Radiography and Imaging
- Bone Tissue Engineering Materials
- Health and Medical Education
- Head and Neck Cancer Studies
- Cancer and Skin Lesions
- Head and Neck Surgical Oncology
- Temporomandibular Joint Disorders
- Oral Health Pathology and Treatment
- Oral and Craniofacial Lesions
- Vascular Malformations and Hemangiomas
- Reconstructive Surgery and Microvascular Techniques
- Orthodontics and Dentofacial Orthopedics
- Soft tissue tumor case studies
Central University Hospital of Asturias
2015-2025
Universidad de Oviedo
2014-2025
Instituto de Investigación Sanitaria del Principado de Asturias
2016-2024
Hospital San Agustin
2002-2022
VA Greater Los Angeles Healthcare System
2021
Geriatric Research Education and Clinical Center
2021
Universidad Nacional Experimental Sur del Lago "Jesús María Semprum"
2017-2018
Biogipuzkoa Health Research Institute
2016
Universidad Autónoma de Chile
2016
University of Southern California
2016
The purpose of this article is to present the authors' experience with use porous polyethylene ultrathin sheets for orbital floor reconstruction. Thirty-two patients fractures were treated sheets. Sixteen cases corresponded orbitozygomatic fractures, 11 pure and five panfacial fractures. subciliary approach was used in 15 transconjunctival nine; another three operated on through a preexisting eyebrow wound, two subtarsal approach, an extension facial one patient wound. Intraoperatively, all...
Aberrations of the p53 gene and overexpression its protein are widely recognized markers malignancy including oral squamous cell carcinomas. This study was performed to evaluate relationship immunoexpression in series 91 carcinomas cavity with clinicopathologic parameters investigate whether might influence clinical outcome disease.From a group 287 consecutive patients, surgically treated ones were randomly selected. P53 expression investigated by means immunohistochemistry. Clinical...
Objetive.To analyze characteristics, clinical evolution and surgical techniques of oroantral communication (OAC).Study Design.We included all patients operated at the University Central Hospital (Oviedo, Spain) between 1996 2007.The variables assessed were age, sex, medical history, OAC size, sinus disease, technique, duration hospitalization post-surgical evolution.Results.We analyzed 12 (7 men 5 women) with an average age 47.5 years.The most frequent cause was extraction first upper...
The reconstruction of bone deficiencies remains a challenge due to the limitations autologous grafting. objective this study is evaluate regeneration efficacy additive manufacturing tricalcium phosphate (TCP) implants using lithography-based ceramic (LCM). LCM uses LithaBone TCP 300 slurry for 3D printing, producing cylindrical scaffolds. Four models internal scaffold geometry were developed and compared. in vitro studies included cell culture, differentiation, seeding, morphological...
The aim of the circular economy is to treat waste as a valuable raw material, reintegrating it into industrial and extending lifecycle subsequent products. Efforts reduce production hard-to-recycle are becoming increasingly important manufacturers, not only consumer goods but also specialized items that difficult manufacture, such medical supplies, which have now become priority for European Union. purpose study manufacture novel human-purified type I collagen membrane from bone remnants...
Repair of bone deficiencies in the craniofacial skeleton remains a difficult clinical problem. The aim this study was to evaluate novel albumin scaffold seeded with human alveolar osteoblasts and implanted into experimental mandibular defects. An solid protein prepared plasmatic crossed glutaraldehyde-type agent. Microstructure mechanical properties were examined using scanning electron microscopy stress-controlled rheometer. Bilateral critical defects created eight immunodeficient rats....
Nuclear imaging plays a crucial role in lymphatic mapping of oral cancer. This evaluation represents subanalysis the original multicenter SENT trial data set, involving 434 patients with T1-T2, N0, and M0 squamous cell carcinoma. The impact acquisition techniques, tracer injection timing relative to surgery, causes false-negative rate were assessed.Three 24 hours before all received dose Tc-nanocolloid (10-175 MBq), followed by lymphoscintigraphy. According institutional protocols, underwent...
Merkel cell carcinoma (MCC) is a very aggressive primary cutaneous neoplasm most often occurring on the head and neck of elderly. Spontaneous regression MCC was first described in 1986. A 79-year-old woman with right cheek underwent spontaneous malignancy, documented by photographic follow-up, computed tomography, histologic studies. review literature presented. Complete clinical observed present case. Although documents 11 similar cases, only 6 can be regarded as complete regressions...
Background: Among the molecular mechanisms involved in carcinogenesis, defects regulation of programmed cell death (apoptosis) make important contributions to pathogenesis and progression cancer. Apoptosis regulatory genes include antiapoptotic bcl‐2 gene proapoptotic bax gene. The aim this study was determine spectrum Bax Bcl‐2 expression, correlate these findings with clinicopathologic variables prognosis. Methods: In we have evaluated immunohistochemical expression proteins a series 35...
Restoration of oral mucosa defects by means in vitro-cultured equivalents has become a valid alternative the field and periodontics surgery. Although different techniques have been described, none able to provide an equivalent with autologous scaffold for epithelium. The purpose this study was obtain complete (CAOME) using patient's own fibroblasts plasma characterize these both morphologically immunohistochemically.We acquired cell types (keratinocytes fibroblasts) from same mucosal...