A5048235893- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Reconstructive Facial Surgery Techniques
- Tracheal and airway disorders
- Cleft Lip and Palate Research
- Tumors and Oncological Cases
- Oral Health Pathology and Treatment
- Oral and Maxillofacial Pathology
- Sarcoma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Colorectal and Anal Carcinomas
- Nonmelanoma Skin Cancer Studies
- Dental Implant Techniques and Outcomes
- Cancer and Skin Lesions
- Bone Tumor Diagnosis and Treatments
- History of Medicine Studies
- Voice and Speech Disorders
- Trauma Management and Diagnosis
- Cancer Immunotherapy and Biomarkers
- Airway Management and Intubation Techniques
- Cutaneous Melanoma Detection and Management
Ospedale Policlinico San Martino
2024
University of Genoa
2024
Ospedale di Bolzano
2018-2024
European Institute of Oncology
2010-2021
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2020
Ripamonti
1998-2017
GTx (United States)
2013
Mylan (Switzerland)
2012
Istituti di Ricovero e Cura a Carattere Scientifico
2006
Institute of Oncology Research
2006
Abstract Background Surgery of tongue tumors includes different procedures ranging from mucosal resection to complex combined resection. Numerous terms have been used describe such procedures, but there is no consensus between the terminology and extent Methods Results We searched medical literature found a lack published information. undertook new classification surgical for tumor based it upon anatomy spread cancer. posited that were five major types glossectomy embracing all methods...
Objective. Squamous cell carcinoma of the nasal vestibule (NV SCC) is a head and neck malignancy for which there no established consensus on most aspects clinical management. The purpose this document to give updated recommendations that incorporate recent evidence its characteristics high efficacy brachytherapy as primary treatment modality. Methods. A working group consisting members Scientific Committee Oncology Reconstructive Surgery Italian Society Otorhinolaryngology Head Neck...
Involvement of the cervical lymph nodes is most important prognostic factor for patients with oral/oropharyngeal squamous cell carcinoma (OSCC), and decision whether to electively treat clinically negative necks remains a controversial topic. Sentinel node biopsy (SNB) provides minimally invasive method determining disease status basin, without need formal neck dissection. This technique potentially improves accuracy histologic nodal staging avoids overtreating three-quarters this patient...
<h3>Objective</h3> To assess the impact of margin status on disease-free survival, overall and organ preservation in early glottic cancer treated by endoscopic laser surgery. <h3>Design</h3> Prospective nonrandomized study. <h3>Setting</h3> Tertiary referral center. <h3>Patients</h3> A total 274 patients with untreated (possibly biopsied) cTis, cT1a/b, cT2, cN0 cancer; adequate exposure region; no contraindications to general anesthesia; ability give informed consent. <h3>Interventions</h3>...
Involvement of the cervical lymph nodes is most important prognostic factor for patients with oral/oropharyngeal squamous cell carcinoma (OSCC), and decision whether to electively treat clinically negative necks remains a controversial topic. Sentinel node biopsy (SNB) provides minimally invasive method determining disease status basin, without need formal neck dissection. This technique potentially improves accuracy histological nodal staging avoids over-treating three-quarters this patient...
Transoral laser microsurgery (TLM) is a mature approach to supraglottic cancer, while transoral robotic surgery (TORS) emerging. The present study compared these approaches.The first 10 patients (2002-2005) given TLM were with the (2007-2011) TORS for cT1-3 cN0-cN2c cancer.A feeding tube was used in four and seven patients. Margins more often positive, but operating times shorter, TORS. All are without evidence of disease, only six remain disease-free after much longer follow-up....
Abstract Background We investigated the role of soft tissue tract between primary tumor and neck lymph nodes, “T‐N tract,” in patients with tongue squamous cell carcinoma at an advanced stage. Methods performed a compartmental surgery 233 patients. Cumulative incidence relapses overall survival curves were compared by T‐N involvement. Multivariate Cox proportional hazards models used to assess independent tract. Results At 4 years follow‐up, disease experienced significantly more distant...
<h3>Objective</h3> To evaluate the prevalence of sublevel IIB lymph node (LN) metastases for head and neck primary tumors in a large cohort patients. <h3>Design</h3> Prospective study. <h3>Setting</h3> One referral university hospital 2 national institutes oncology. <h3>Patients</h3> Between 2003 2005, 297 patients (male to female ratio, 3.5:1; mean age, 58.8 years [range, 18-89 years]) affected by cancer were treated surgery on tumor and/or neck. Primary site distribution included...
The aim of the study was to evaluate impact COVID-19 pandemic on new diagnoses head and neck cancer (HNC) in South Tyrol, northern Italy terms number worsening disease stage due diagnostic delay.Patients were divided into two groups: control group with a first diagnosis HNC 10 months before national lockdown (March 9th, 2020) after lockdown.A total 124 patients included study. Before spread COVID-19, 79 HNCs registered, while period lockdown, 45 cancers cases diagnosed difference...
Objective The local spread of oral tongue squamous cell carcinoma (OTSCC) follows pathways dissemination along areas lesser resistance. In more advanced scenarios, the tumor can extend beyond hemi-tongue origin, by passing through lingual septum and following fibers transverse muscle. This lead to invasion contralateral extrinsic muscles, first being genioglossus laterally hyoglossus. An anatomically guided surgical resection be planned ensure both oncological safety an acceptable functional...
The DOK1 gene is a putative tumour suppressor located on the human chromosome 2p13 which frequently rearranged in leukaemia and other tumours. We previously reported that can be mutated its expression down-regulated malignancies. However, mechanism underlying silencing remains largely unknown. show here unscheduled of through aberrant hypermethylation frequent event variety was found to silenced nine head neck cancer (HNC) cell lines studied CpG correlated with loss these cells. could...