A5007987234- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Radiation Therapy and Dosimetry
- Dysphagia Assessment and Management
- Medical Imaging Techniques and Applications
- Oral health in cancer treatment
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Radiation Dose and Imaging
- Sinusitis and nasal conditions
- Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Tracheal and airway disorders
- Brain Metastases and Treatment
- Nutrition and Health in Aging
- Frailty in Older Adults
- Ethics in Clinical Research
- Reconstructive Surgery and Microvascular Techniques
- Effects of Radiation Exposure
- Esophageal and GI Pathology
- Cancer, Hypoxia, and Metabolism
Aarhus University Hospital
2015-2024
Dansk Sygehus Institut
2024
Aarhus University
1957-2024
Novozymes (Denmark)
2022
Centre for Cosmology and Particle Physics Phenomenology
2019-2020
Nordic Lymphoma Group
1981
Aarhus Municipality
1979
Copenhagen Municipal Hospital
1964-1970
The objective of this study was to pilot test an updated version the European Organization for Research and Treatment Cancer Quality Life Questionnaire Head Neck Module (EORTC QLQ-H&N60).Patients with head neck cancer were asked complete a list 60 cancer-specific items comprising EORTC module core questionnaire QLQ-C30. Debriefing interviews conducted identify any irrelevant confusing or upsetting wording.Interviews performed 330 patients from 17 countries, representing different sites...
IntroductionProton treatment can potentially spare patients with H&N cancer for substantial treatment-related toxicities. The current study investigated the reproducibility of a decentralised model-based selection proton when plans were compared to clinical performed at centre.MethodsSixty-three selected in six Danish Head and Neck Cancer (DAHANCA) centres. based on normal tissue complication probability (NTCP) estimated from local photon plans, which showed ΔNTCP greater than 5%-point...
Aspiration and aspiration pneumonia has been reported with a high incidence in head neck cancer populations treated chemo-radiotherapy. The aim of this study was to investigate the mortality an unselected series patients curative radiotherapy or without concurrent weekly cisplatin.A total 324 consecutive intended for single Danish referral center Aarhus from 2006 2008 were included followed median 4.3 years. Data on patient, tumor treatment characteristics obtained DAHANCA database. hospital...
Introduction. The aim of the study was to assess value EORTC questionnaires C30 and H&N35, as an instrument for side effects. Patients methods. We invited all recurrence free patients, treated with radical radiotherapy pharyngeal cancer between 1998 2002 at our institution, participate in study. Data retrieved using questionnaires, functional endoscopic evaluation swallowing, dental examination orthopantomography saliva flow measurements. Thirty-five (55% invited) participated. Results. Side...
Background. Dysphagia is a common and debilitating side effect in head neck radiotherapy (RT). Prognostic factors are numerous their interrelationship not well understood. The aim of this study was to establish multivariate prognostic model for acute late dysphagia after RT, based on information from prospective trial. Material methods. DAHANCA 6&7 randomized included 1476 patients with cancer eligible primary RT alone. Patients were between 5 6 weekly fractions conventional received 62–70...
Adaptive (ART) and image guided radiation therapy (IGRT) can improve target coverage reduce unnecessary irradiation of organs at risk (OAR). The purpose this study is to report the results using mid-course imaging a novel workflow with cone-beam computed tomography (CBCT) surveillance dose OAR trigger adaptive replanning in head neck radiotherapy.Impact therapist (RTT) managed match protocol was assessed two cohorts consecutive patients receiving RT region, (CT) CBCT-based verification...
Objectives: The purposes were to investigate the health status of elderly cancer patients by comprehensive geriatric assessment (CGA) and compare complications with respect baseline CGA evaluate need for interventions in an patients' population.Material: Patients aged ≥70 years lung (LC), head neck (HNC), colorectal (CRC), or upper gastro-intestinal (UGIC) are referred Department Oncology treatment.Methods: was performed prior treatment addressed following domains: Activities daily living...
Introduction: Prediction models using logistic regression may perform poorly in external patient cohorts. However, there is a need to standardize and validate for clinical use. The purpose of this project was describe method validation NTCP used selection the randomized trial protons versus photons head neck cancer radiotherapy, DAHANCA 35.Material methods: Organs at risk 588 patients treated primarily with IMRT controlled DAHANCA19 were retrospectively contoured according recent...
The study comprises observations of Se.Cu changes in 29 patients with Hodgkin's disease during treatment cancertherapeutics and roentgen. It appears that these alterations follow the clinical condition closely, they can be used evaluation therapeutic effect. are often pronounced appear early, first indications Consequenetly, determination will prognostic value treatment. Favourable effect applied therapy, improvement condition, is always accompanied by a decrease Se.Cu. Absence fall seems...
Autocontouring improves workflow in computed tomography (CT)-based dose planning, but could also potentially play a role for optimal use of daily cone beam CT (CBCT) adaptive radiotherapy. This study aims to determine the accuracy deformable image registration (DIR) algorithm organs at risk (OAR) neck region, when applied CBCT.For 30 head and cancer (HNC) patients 14 OARs including parotid glands, swallowing structures spinal cord were delineated. Contours propagated by DIR from CBCTs first...