A5020362726- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Cancer survivorship and care
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Dysphagia Assessment and Management
- Nutrition and Health in Aging
- Sinusitis and nasal conditions
- Otolaryngology and Infectious Diseases
- Tumors and Oncological Cases
- Bone Tumor Diagnosis and Treatments
- Lung Cancer Treatments and Mutations
- Oral and Maxillofacial Pathology
- Oral health in cancer treatment
- Surgical site infection prevention
- Voice and Speech Disorders
- Ear and Head Tumors
- Multiple and Secondary Primary Cancers
- Hip and Femur Fractures
- Brain Metastases and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Liver Diseases and Immunity
- Microscopic Colitis
- Meningioma and schwannoma management
- Toxoplasma gondii Research Studies
IPO Porto
2014-2024
Instituto Português de Oncologia Francisco Gentil
2012-2024
Universidade de São Paulo
2001-2021
Escola Superior de Saúde do Alcoitão
2017
University of Aveiro
2017
Abstract Background We validated the new European Organisation for Research and Treatment of Cancer Quality Life Head Neck Module (EORTC QLQ‐HN43). Methods enrolled 812 patients with head neck cancer from 18 countries. Group 1 completed questionnaire before therapy, 3 6 months later. In group 2 (survivors), we determined test–retest reliability using intraclass correlation coefficients (ICC). Internal consistency was assessed Cronbach's Alpha, scale structure confirmatory factor analysis,...
Abstract Head and neck cancer (HNC) patients suffer from a range of health‐related quality life (HRQoL) issues, but little is known about their long‐term HRQoL. This study explored associations between treatment group HRQoL at least 5 years' post‐diagnosis in HNC survivors. In an international cross‐sectional study, survivors completed the European Organization for Research Treatment Cancer (EORTC) core questionnaire (EORTC‐QLQ‐C30) its module (EORTC‐QLQ‐H&N35). Meaningful differences...
The objective of this study was to pilot test an updated version the European Organization for Research and Treatment Cancer Quality Life Questionnaire Head Neck Module (EORTC QLQ-H&N60).Patients with head neck cancer were asked complete a list 60 cancer-specific items comprising EORTC module core questionnaire QLQ-C30. Debriefing interviews conducted identify any irrelevant confusing or upsetting wording.Interviews performed 330 patients from 17 countries, representing different sites...
The long-term problems of head and neck cancer survivors (HNCS) are not well known. In a cross-sectional international study aimed at exploring the quality life in this population, 1114 HNCS were asked to state their two most serious effects. A clinician recorded responses during face-to-face appointments. list 15 example was provided, but free text field also available. total 1033 responded question. frequent 'dry mouth' (DM) (n = 476; 46%), 'difficulty swallowing/eating' (DSE) 408; 40%),...
To evaluate the clinical and histopathological factors affecting prognosis of patients with squamous cell locoregional advanced laryngeal cancer.A retrospective chart review was conducted 121 cancer, primarily treated surgery from 2007 to 2011. Disease-free survival overall rates were analysed as oncological outcomes. Prognostic variables, namely gender, pharyngeal invasion, pathological assessment tumour nodal stage, adjuvant therapy, margin status, extracapsular extension, differentiation,...
Serum samples from 37 captive exotic felids in 12 zoos six Brazilian states were assayed for antibodies to Toxoplasma gondii by the modified agglutination test using formalin-fixed whole tachyzoites. Titers greater than or equal 1:20 considered positive. Antibodies T. found 24 of (64.9%) felids, including one European lynx (Lynx lynx), two jungle cats (Felis chaus), servals (Leptailurus serval), tigers (Panthera tigris), three leopards pardus), and 14 27 lions leo). This is first serologic...
The management of cervical lymph node metastases from an unknown primary tumor remains a controversial subject. Recently, Positron Emission Tomography (PET) has proved useful in the detection these tumors, even after unsuccessful conventional diagnostic workup. This study was performed to assess role PET occult head and neck carcinomas.A retrospective analysis four year period at tertiary referral oncology hospital conducted.Of 49 patients with carcinoma primary, detected 9 gave 5 false...
The aim of this study was to explore what methods should be used determine the minimal important difference (MID) and change (MIC) in scores for European Organisation Research Treatment Cancer Head Neck Module, EORTC QLQ-HN43.In an international multi-centre study, patients with head neck cancer completed QLQ-HN43 before onset treatment (t1), three months after baseline (t2), six (t3). explored determining MID were: (1) group comparisons based on performance status; (2) 0.5 0.3 standard...
Introduction and Objectives: Sinonasal tumours represent only 3% of all head neck cancers. Adenocarcinoma is the second most frequent histopathology type. Hardwood exposure has been considered a risk factor. adenocarcinoma grows silently which leads to late diagnosis low survival rates. The aim this study was present our experience in management patients with sinonasal adenocarcinoma. Method: Retrospective medical records review adenocarcinomas (1974 2009). Results: From 301 tumors, 67 had...
Introduction: Total laryngectomy/pharingo-laryngectomy is a potentially aggressive surgery for advanced laryngeal/hypopharyngeal carcinomas, which results in important physical and functional changes that compromise some of the most vital functions, including speech communication. For these patients, tracheoesophageal considered to be gold standard voice rehabilitation. Objectives: The purpose present study was determinate success rate prosthesis rehabilitation, lifetime complications, its...
Malnutrition in Head and neck cancer (HNC) patients can be present at the moment of diagnosis. The nutritional status is determinant for treatment success quality life patients. gradually declines during majority undergoing will need therapy. On other hand, HNC, like cancers, induce a paraneoplastic syndrome that leads to cachexia. This cachexia most times cause death or failure. So, early identification malnutrition high risk crucial start an adequate nutrition support intervention HNC...
To correlate voice prosthesis devices (VP) with intelligibility and quality of life in laryngectomized patients (QoLLP).Methods: C30 H&N35 questionnaires European Organization for Research Treatment Cancer (EORTC) Harrinson Robillard-Schultz Rating Scale tracheoesophageal were used to evaluate 61 submitted total laryngectomy or pharyngolaryngectomy rehabilitated primary secondary (VP).Results: A moderate but statistically significant correlation between the regular use VP was verified.No...
Abstract Purpose The aim of this study was to explore what methods should be used determine the minimal important difference (MID) and change (MIC) in scores for European Organisation Research Treatment Cancer Head Neck Module, EORTC QLQ-HN43. Methods In an international multi-centre study, patients with head neck cancer completed QLQ-HN43 before onset treatment (t1), three months after baseline (t2), six (t3). explored determining MID were: 1) group comparisons based on performance status;...