A5078183009- Head and Neck Cancer Studies
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Galectins and Cancer Biology
- Salivary Gland Disorders and Functions
- S100 Proteins and Annexins
- Protein Tyrosine Phosphatases
- Oral Health Pathology and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Oral microbiology and periodontitis research
- Protease and Inhibitor Mechanisms
- Peptidase Inhibition and Analysis
Instituto Português de Oncologia Francisco Gentil
2023-2024
IPO Porto
2023-2024
University of Aveiro
2023-2024
Introduction Saliva has gained increasing attention in the quest for disease biomarkers. Because it is a biological fluid that can be collected an easy, painless, and safe way, been increasingly studied identification of oral cancer This particularly important because often diagnosed at late stages with poor prognosis.
Head and Neck Squamous Cell Carcinoma (HNSCC) is a malignant cancer with poor prognosis. Galectins (Gal) have been the subject of intensive research, but comparative prognostic value each Gal type not yet understood. Therefore, literature search for evaluating galectins as biomarkers in HNSCC was conducted. The relationship between expression HPV TP53 mutational status assessed using UALCAN database. impact these on prognosis analyzed ToPP CPPA web tools. tumor microenvironment depending...
Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant cancers in world. In advanced stages, mortality rate high. Stratification HNSCC patients by molecular characteristics allows optimization clinical management these patients. Here, we explored GEO PRIDE Databases to identify putative prognostic biomarkers for HNSCC. Thus, an integrated transcriptome analysis was performed major differentially expressed genes tissues (using GSE12452, GSE13597, GSE31056, GSE6631...
Head and Neck Squamous Cell Carcinoma (HNSCC) is a malignant cancer with poor prognosis. Currently, the prognosis of HNSCC determined by clinical histopathological criteria. This work focused on identifying panel genes that have potential to be used for improve patient stratification treatment. To this end, bibliometric analysis (VosViewer) was applied identify candidate were further characterized applying several bioinformatics tools (UALCAN, ToPP). The prognostic interest evaluated using...