- Cancer survivorship and care
- Head and Neck Cancer Studies
- Nutritional Studies and Diet
- Childhood Cancer Survivors' Quality of Life
- Health Systems, Economic Evaluations, Quality of Life
- Diet and metabolism studies
- Economic and Financial Impacts of Cancer
- Oral health in cancer treatment
- Cancer Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Colorectal Cancer Surgical Treatments
- Dysphagia Assessment and Management
- Lung Cancer Treatments and Mutations
- Management of metastatic bone disease
- Bone health and osteoporosis research
- Bone health and treatments
- Thyroid Cancer Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Colorectal and Anal Carcinomas
- Nutrition and Health in Aging
- Vitamin D Research Studies
- Metabolism, Diabetes, and Cancer
- Cancer Risks and Factors
- Estrogen and related hormone effects
- Frailty in Older Adults
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2022
Centro di Riferimento Oncologico
2021
Hospital of St. Francis Xavier
2010-2020
Tumori Foundation
2020
Jagiellonian University
2016
Complejo Hospitalario de Navarra
2016
Sahlgrenska University Hospital
2016
University of Valparaíso
2015
The number of cancer survivors is growing steadily and increasingly, clinical trials are being designed to include long-term follow-up assess not only survival, but also late effects health-related quality life (HRQOL). Therefore it essential develop patient-reported outcome measures (PROMs) that capture the full range issues relevant disease-free survivors. objectives this project are: 1) a European Organisation for Research Treatment Cancer (EORTC) questionnaire captures physical, mental...
The European Organisation for Research and Treatment of Cancer (EORTC) Group has developed a new multidimensional instrument measuring cancer-related fatigue to be used in conjunction with the quality life core questionnaire (EORTC QLQ-C30). module EORTC QLQ-FA13 assesses physical, cognitive, emotional aspects fatigue.The methodology follows guidelines phase IV validation modules. This paper focuses on results psychometric factorial structure module. For cross-validation confirmatory factor...
Abstract Background We validated the new European Organisation for Research and Treatment of Cancer Quality Life Head Neck Module (EORTC QLQ‐HN43). Methods enrolled 812 patients with head neck cancer from 18 countries. Group 1 completed questionnaire before therapy, 3 6 months later. In group 2 (survivors), we determined test–retest reliability using intraclass correlation coefficients (ICC). Internal consistency was assessed Cronbach's Alpha, scale structure confirmatory factor analysis,...
Healthy lifestyles are associated with better health-related quality of life (HRQoL), favorable prognosis and lower mortality in breast cancer (BC) survivors. We investigated changes HRQoL after a 12-month lifestyle modification program 227 BC survivors participating DEDiCa trial (Mediterranean diet, exercise, vitamin D). was evaluated through validated questionnaires: EQ-5D-3L, EORTC-QLQ-C30 EORTC QLQ-BR23. Baseline were tested using analysis variance. Multiple regression analyses performed...
Abstract Head and neck cancer (HNC) patients suffer from a range of health‐related quality life (HRQoL) issues, but little is known about their long‐term HRQoL. This study explored associations between treatment group HRQoL at least 5 years' post‐diagnosis in HNC survivors. In an international cross‐sectional study, survivors completed the European Organization for Research Treatment Cancer (EORTC) core questionnaire (EORTC‐QLQ‐C30) its module (EORTC‐QLQ‐H&N35). Meaningful differences...
The objective of this study was to pilot test an updated version the European Organization for Research and Treatment Cancer Quality Life Questionnaire Head Neck Module (EORTC QLQ-H&N60).Patients with head neck cancer were asked complete a list 60 cancer-specific items comprising EORTC module core questionnaire QLQ-C30. Debriefing interviews conducted identify any irrelevant confusing or upsetting wording.Interviews performed 330 patients from 17 countries, representing different sites...
Evidence suggests a beneficial role of the Mediterranean Diet (MedDiet) on health-related quality life (HRQoL) in healthy subjects. HRQoL is relevant cancer therapy and disease outcomes, therefore we investigated association between adherence to MedDiet breast survivors participating multicentre trial DEDiCa. were assessed at baseline subgroup 309 women enrolled within 12 months diagnosis without metastasis (stages I-III, mean age 52±1 yrs, BMI 27±7 kg/m2). The 14-item PREDIMED questionnaire...
Abstract Purpose Surgical complications such as hypoparathyroidism (HPT) or vocal cord palsy are seldom assessed when the quality of life (QOL) in thyroid cancer patients is investigated. The aim this study was to measure QOL difference survivors with and without HPT. Methods Participants for analysis were enrolled 13 countries from a that pilot-tested cancer–specific instrument. They included if they had been diagnosed at least 9 months previously. measured using European Organisation...
The long-term problems of head and neck cancer survivors (HNCS) are not well known. In a cross-sectional international study aimed at exploring the quality life in this population, 1114 HNCS were asked to state their two most serious effects. A clinician recorded responses during face-to-face appointments. list 15 example was provided, but free text field also available. total 1033 responded question. frequent 'dry mouth' (DM) (n = 476; 46%), 'difficulty swallowing/eating' (DSE) 408; 40%),...
International Guidelines as well Cancer Associations recommend a multidisciplinary approach to lung cancer care. A team (MDT) can significantly improve treatment decision-making and patient coordination by putting different physicians other health professionals “in the same room”, who collectively decide upon best possible treatment. However, this is not panacea for The impact of care (MDC) on outcomes univocal, while effective functioning MDT depends many factors. This review presents...
Introdução: Terapias de mobilização e manipulação são amplamente utilizadas para beneficiar pacientes com dor lombar crônica. É possível observar uma correlação entre a dor, redução da amplitude movimento diminuição flexibilidade, que aumenta gravidade do quadro DL. Objetivo: Comparar os efeitos imediatos articular vertebral local ou distal sobre mobilidade, força resistência coluna em indivíduos adultos jovens. Métodos: A amostra foi composta por 40 idade 18 35 anos, ambos sexos, foram...
The purpose of the study was to pilot-test a questionnaire measuring health-related quality life (QoL) in thyroid cancer patients be used with European Organisation for Research and Treatment Cancer (EORTC) core EORTC QLQ-C30. A provisional 47 items administered treated within last 2 years. Patients were interviewed about time help needed complete questionnaire, whether they found understandable, confusing or annoying. Items kept if fulfilled pre-defined criteria: relevant patients, easy...
A multidisciplinary panel of experts and cancer patients developed a position paper to highlight recent evidence on "cancer cure" (ie, the possibility achieving same life expectancy as general population) discuss consequences this concept follow-up rehabilitation strategies. The aim is inform clinicians, patients, health-care policy makers about strategies survivorship care for cured impacting patient lives, spurring public health authorities research organizations implement resources...
Health related quality of life (HRQoL) is an important recognized health outcome for cancer treatments, but also disease course with slower recovery and increased morbidity. These issues are implication in melanoma, which maintains a risk progression many years after diagnosis. This study aimed to explore weigh factors the perception possible relationships demographic-clinical characteristics people melanoma via machine learning approach. In this observational study, patients without...
Mechanisms influencing breast cancer (BC) development and recurrence include hyperglycemia, hyperinsulinemia, high insulin-like growth factor-1, circulating estrogen, inflammation impaired cellular differentiation/apoptosis. A lifestyle program that targets all the above mechanisms may be warranted. Low glycemic index (GI) foods produce lower post-prandial glucose insulin responses have been associated with BC risk. Moderate physical activity post-diagnosis reduces mortality, partly...
Management of COVID-19 post-acute syndrome is an emerging health issue in rehabilitation. This article aims to present a proposal, based on the principles clinical governance, management and information technology (IT), respond need for structured organization model The authors regional-based network clinicians healthcare managers using dedicated IT platform achieve both effectiveness efficiency objectives, ensure coordination available resources most appropriate rehabilitative treatment...