A5091319902- Cancer Risks and Factors
- Metabolism, Diabetes, and Cancer
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Hepatitis C virus research
- Nutritional Studies and Diet
- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Viral-associated cancers and disorders
- Breast Cancer Treatment Studies
- Hepatitis B Virus Studies
- Lymphoma Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- BRCA gene mutations in cancer
- Glutathione Transferases and Polymorphisms
- Diet, Metabolism, and Disease
- Prostate Cancer Treatment and Research
- Diet and metabolism studies
- Bladder and Urothelial Cancer Treatments
- Genomics, phytochemicals, and oxidative stress
- Cutaneous Melanoma Detection and Management
- MicroRNA in disease regulation
- Coffee research and impacts
- Genetic factors in colorectal cancer
- Alcohol Consumption and Health Effects
Centro di Riferimento Oncologico
2012-2021
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2020
Tumori Foundation
2020
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2010-2019
Cancer Institute (WIA)
2006-2017
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2017
MRC Epidemiology Unit
2013
Regione Campania
2003-2008
National Cancer Institute
2005
National Cancer Registry
2004
The proportion of colorectal cancer attributed to dietary habits is high, but several inconsistencies remain, especially with respect the influence some food groups. To further elucidate role habits, 1,225 subjects colon, 728 rectum and 4,154 controls, hospitalized acute non-neoplastic diseases, were interviewed between 1992 1996 in 6 different Italian areas. validated food-frequency questionnaire included 79 questions on items recipes, categorised into 16 After allowance for non-dietary...
Abstract Mortality rates of hepatocellular carcinoma (HCC) are high in Italy compared with other Western countries. To elucidate further the role hepatitis B virus (HBV), C (HCV), alcohol drinking, and tobacco smoking etiology HCC, we carried out a hospital-based case-control study two areas Italy: province Pordenone Northeast town Naples South. A total 229 HCC cases (median age, 66 years) 431 controls 65 answered questionnaire provided blood samples between 1999 2002. Odds ratios (OR),...
Hepatocellular carcinoma (HCC) has been associated to diabetes and obesity, but a possible association with the metabolic syndrome (MetS) its potential interaction hepatitis is open discussion. We analysed data from an Italian case–control study, including 185 HCC cases 404 controls. Odds ratios (ORs) 95% confidence intervals (CIs) were computed unconditional logistic regression models. Among MetS components, obesity (i.e, body mass index (BMI)⩾30 kg m−2) positively risk, ORs of 4.33 (95%...
Postmenopausal women show the highest incidence of breast cancer in female population and are often affected by metabolic syndrome. Metabolic syndrome (MS) - characterized central adiposity, insulin resistance, low serum high-density lipoprotein cholesterol (HDL-C), high triglyceride blood pressure seems to be strictly correlated carcinogenesis. We enrolled 777 healthy with our nested case-control study evaluate association between MS cancer, analyzing anthropometric parameters (weight,...
Diabetes has been associated to the risk of a few cancer sites, though quantification this association in various populations remains open discussion. We analyzed relation between diabetes and cancers an integrated series case-control studies conducted Italy Switzerland 1991 2009. The included 1,468 oral pharyngeal, 505 esophageal, 230 gastric, 2,390 colorectal, 185 liver, 326 pancreatic, 852 laryngeal, 3,034 breast, 607 endometrial, 1,031 ovarian, 1,294 prostate, 767 renal cell cases 12,060...
Hepatitis C virus (HCV) has been consistently associated to non-Hodgkin lymphoma (NHL); conversely, few studies have evaluated a comprehensive serological panel of hepatitis B (HBV) in NHL etiology.
Evidence suggests a beneficial role of the Mediterranean Diet (MedDiet) on health-related quality life (HRQoL) in healthy subjects. HRQoL is relevant cancer therapy and disease outcomes, therefore we investigated association between adherence to MedDiet breast survivors participating multicentre trial DEDiCa. were assessed at baseline subgroup 309 women enrolled within 12 months diagnosis without metastasis (stages I-III, mean age 52±1 yrs, BMI 27±7 kg/m2). The 14-item PREDIMED questionnaire...
Abstract HCV has been associated with NHL, but the evidence from case series and case‐control studies is not totally consistent. Between 1999 2002, we conducted a hospital study on association between HCV, HBV NHL in 2 areas of Italy where infection relatively frequent. Cases ( n = 225, median age 59 years) were consecutive patients new diagnosis admitted to local specialized general hospitals. Controls 504, 63 wide spectrum acute conditions same hospitals as cases. prevalence was 19.6%...
The role of diet, except for alcohol drinking and aflatoxin contamination, in the etiology hepatocellular carcinoma (HCC) is unclear. A hospital-based case-control study was conducted Italy 1999-2002, including 185 incident, histologically-confirmed cases HCC. Controls were 412 subjects admitted to hospitals acute, nonneoplastic diseases unrelated diet. Dietary habits assessed using a validated food-frequency questionnaire. Odds ratios (ORs) corresponding 95% confidence intervals (CI)...
Abstract The role of coffee in the aetiology hepatocellular carcinoma has raised great interest. In Italy, consumption is high, thus allowing investigation topic over a broad range consumption. A hospital‐based case‐control study was conducted Italy 1999–2002, including 185 incidents, histologically confirmed cases aged 43–84 years. Controls were 412 subjects admitted to same hospitals' networks for acute, non‐neoplastic diseases unrelated diet. Coffee and tea assessed using validated...
Abstract Intake of flavonoids has been inversely related to the risk various common neoplasms, but limited data exist on renal cell carcinoma (RCC). We used from a case-control study conducted between 1994 and 2002 in four Italian areas relation major flavonoid classes RCC. The included 767 cases with incident, histologically confirmed RCC 1,534 hospital controls admitted for acute, nonneoplastic conditions matched by center, sex, quinquennia age. applied published food beverage content six...
Stage shift is widely considered a major determinant of the survival benefit conferred by breast cancer screening. However, factors and mechanisms underlying such prognostic advantage need further clarification. We sought to compare molecular characteristics screen detected vs. symptomatic cancers assess whether differences in tumour biology might translate into benefit. In clinical series 448 women with operable cancer, Kaplan-Meier method log-rank test were used estimate likelihood...
Abstract Inflammation and diet have been suggested to be important risk factors for hepatocellular cancer (HCC). This Italian multicentre hospital-based case–control study conducted between 1999 2002 including 185 cases with incident, histologically confirmed HCC, 404 controls hospitalised acute non-neoplastic diseases provided an opportunity investigate the association HCC dietary inflammatory index (DII). The DII was computed on basis of intake assessed 2 years before date interview by a...
The Metabolic syndrome (MetS) is an emerging condition worldwide, consistently associated with increased risk of several cancers. Some information exists on urothelial carcinoma the bladder (UCB) and MetS. This study aims at further evaluating association between MetS UCB. Between 2003 2014 in Italy, we conducted a hospital-based case-control study, enrolling 690 incident UCB patients 665 cancer-free matched patients. was defined as presence least three four selected indicators: abdominal...