A5043102004- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cancer Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Lung Cancer Research Studies
- Radiopharmaceutical Chemistry and Applications
- Oral health in cancer treatment
- Medical Imaging Techniques and Applications
- Colorectal and Anal Carcinomas
- Cancer survivorship and care
- Dysphagia Assessment and Management
- Cancer Immunotherapy and Biomarkers
- Sinusitis and nasal conditions
- Tumors and Oncological Cases
- Brain Metastases and Treatment
- Neuroendocrine Tumor Research Advances
- Esophageal Cancer Research and Treatment
- Management of metastatic bone disease
- Esophageal and GI Pathology
Rigshospitalet
2016-2025
Copenhagen University Hospital
2015-2025
University of Copenhagen
2010-2022
European Organisation for Research and Treatment of Cancer
2021
UW Health University Hospital
2017
Madison Group (United States)
2017
Gentofte Hospital
2013
Herlev Hospital
2001
University of Colorado Denver
2001
University of Colorado Cancer Center
2001
HPV is found in head and neck cancer from all sites with a higher prevalence oropharynx (OPC) compared to non-OPC. HPV/p16-status has significant impact on radiotherapy (RT) outcome advanced OPC, but less known about the influence We analyzed HPV-associated p16-expression cohort of patients stage III-IV pharynx larynx treated primary, curatively intended (chemo-)RT, aiming test hypothesis that HPV/p16 also extends tumors non-oropharyngeal origin.1294 enrolled previously conducted...
Intratumor heterogeneity may contribute to the ambiguous clinical results on PD-L1 status as a predictor for immunotherapy response in patients with HNSCC. This decreases utility of expression from single tumour biopsies predictive biomarker. In this prospective study, intratumor HNSCC was investigated both Tumour Proportion Score (TPS) and Combined Positive (CPS). Thirty-three whole surgical specimens 28 were included. six random core each specimen used assess concordance between multiple...
Head and neck squamous cell carcinoma (HNSCC) is primarily caused by smoking alcohol. Besides having a carcinogenic effect, also leads to other diseases thus contributes high prevalence of comorbidities among HNSCC patients. Furthermore, the world population becoming older resulting in more elderly patients with HNSCC. The aim this study was investigate impact comorbidity retrospective nationwide population-based all Danish diagnosed from 1992 2008.A total 12 623 period 2008 were identified...
Reliable and accessible biomarkers for patients with Head Neck Squamous Cell Carcinoma (HNSCC) are warranted biologically driven radiotherapy (RT). This study aimed to investigate the prognostic value of putative cancer stem cell (CSC) markers, hypoxia, tumor volume using loco-regional high-dose failure (HDF) as endpoint.
Objective. To evaluate the treatment outcome for sino-nasal carcinomas in Denmark from 1995–2004 and compare results to previous Danish survey covering 1982–1991. Design. Retrospective follow-up. Materials methods. In five head neck oncology centres, charts of all consecutive patients with were reviewed data extracted a common database. Altogether 242 period identified. Of these 162 (67%) male 80 (33%) female. Histologies included squamous cell carcinoma (55%), adenocarcinoma (28.5%),...
Background and purpose: The randomised clinical trial KEYNOTE-048 has demonstrated a significant increase in survival for patients with head neck cancer treated pembrolizumab or without chemotherapy. purpose of the present retrospective study was to investigate whether group consecutive at our department comparable results from KEYNOTE-048. Patients/material methods: Seventy-six initiated treatment ± platinum/5-FU between July 2020 May 2022. Baseline characteristics were collected, response...
Background. The post-treatment follow-up is well-integrated in the oncologic care tradition, based on risk of developing recurrent disease or new primary tumors treated patients. Furthermore, serves as an opportunity to monitor treatment effects and provide clinical side effects. In this study we measured activity effectiveness routine head neck cancer assessed value from perspectives both physicians Patients methods. During a period six weeks prospective national cross section cohort 619...
Introduction: Prediction models using logistic regression may perform poorly in external patient cohorts. However, there is a need to standardize and validate for clinical use. The purpose of this project was describe method validation NTCP used selection the randomized trial protons versus photons head neck cancer radiotherapy, DAHANCA 35.Material methods: Organs at risk 588 patients treated primarily with IMRT controlled DAHANCA19 were retrospectively contoured according recent...
The study was undertaken in order to compare dose plans for intensity-modulated radiotherapy (IMRT) with 3D conformal (3D-CRT) patients nasopharyngeal carcinoma (NPC). Clinical data from 20 consecutive treated IMRT are presented. For 11 3D-CRT were made and compared the respect doses planning target volumes (PTVs) organs at risk (OARs). comparison of conformation defined conformity index (CI) used. Target volume coverage critical organ protection significantly improved 3D-CRT. One-year...