Michael T. Brennan

ORCID: 0000-0003-0638-4335
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About
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Research Areas
  • Oral health in cancer treatment
  • Salivary Gland Disorders and Functions
  • Head and Neck Cancer Studies
  • Oral Health Pathology and Treatment
  • Cancer Diagnosis and Treatment
  • Salivary Gland Tumors Diagnosis and Treatment
  • Oral microbiology and periodontitis research
  • Infective Endocarditis Diagnosis and Management
  • Systemic Lupus Erythematosus Research
  • Oral and gingival health research
  • Streptococcal Infections and Treatments
  • Oral and Maxillofacial Pathology
  • Ocular Surface and Contact Lens
  • Otolaryngology and Infectious Diseases
  • Atrial Fibrillation Management and Outcomes
  • Systemic Sclerosis and Related Diseases
  • Hematopoietic Stem Cell Transplantation
  • Galectins and Cancer Biology
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Nosocomial Infections in ICU
  • Dental Anxiety and Anesthesia Techniques
  • Gut microbiota and health
  • Immunodeficiency and Autoimmune Disorders
  • Dental Implant Techniques and Outcomes
  • Cleft Lip and Palate Research

Carolinas Medical Center
2016-2025

Wake Forest University
2021-2024

Robert Gordon University
2024

Jacobs (United States)
2024

Atrium Medical Cente
2024

Carolinas Healthcare System
2016-2018

University of Toronto
2017

VA Boston Healthcare System
2015

North York General Hospital
2009

Novant Health Forsyth Medical Center
2008

Antibiotic prophylaxis recommendations for the prevention of infective endocarditis are based in part on studies bacteremia from dental procedures, but toothbrushing may pose a greater threat. The purpose this study was to compare incidence, duration, nature, and magnitude endocarditis-related single-tooth extraction determine impact amoxicillin extraction.In double-blind, placebo-controlled study, 290 subjects were randomized (1) toothbrushing, (2) with prophylaxis, or (3) identical...

10.1161/circulationaha.107.758524 article EN Circulation 2008-06-10

Abstract Objective To assess the safety and potential efficacy of etanercept in treatment Sjögren's syndrome (SS). Methods This pilot study was a 12‐week randomized, double‐blind, placebo‐controlled trial etanercept, with 14 subjects each group. Patients received 25 mg or placebo (vehicle) by twice‐weekly subcutaneous injection. met American‐European Consensus Group criteria for SS. The primary outcome required at least 20% improvement from baseline values 2 following 3 domains: subjective...

10.1002/art.20299 article EN Arthritis & Rheumatism 2004-07-01

Trauma intensive care unit (TICU) patients requiring mechanical respiratory support frequently develop ventilator-associated pneumonia (VAP). Oral and oropharyngeal bacteria are believed to be responsible for many cases of VAP, but definitive evidence this relationship is lacking. Earlier studies used conventional culture-based methods identification bacterial pathogens, these insufficient, as some may uncultivable or difficult grow. The purpose study was use a culture-independent molecular...

10.1128/jcm.01963-06 article EN Journal of Clinical Microbiology 2007-02-15

Objective More than 80% of autoimmune disease predominantly affects females, but the mechanism for this female bias is poorly understood. We suspected that an X chromosome dose effect accounts this, and we undertook study to test our hypothesis trisomy (47,XXX; occurring in ∼1 1,000 live births) would be increased patients with female‐predominant diseases (systemic lupus erythematosus [SLE], primary Sjögren's syndrome [SS], biliary cirrhosis, rheumatoid arthritis [RA]) compared without...

10.1002/art.39560 article EN Arthritis & Rheumatology 2015-12-29
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