Guilherme Eduardo Gonçalves Felga

ORCID: 0000-0002-0676-4867
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Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Viral-associated cancers and disorders
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Pancreatitis Pathology and Treatment
  • Hepatitis C virus research
  • Renal Transplantation Outcomes and Treatments
  • Liver Diseases and Immunity
  • Organ Donation and Transplantation
  • Gallbladder and Bile Duct Disorders
  • Abdominal Trauma and Injuries
  • Gastroesophageal reflux and treatments
  • Clinical Nutrition and Gastroenterology
  • Helicobacter pylori-related gastroenterology studies
  • Hepatitis B Virus Studies
  • Pancreatic and Hepatic Oncology Research
  • Acute Lymphoblastic Leukemia research
  • Hepatitis Viruses Studies and Epidemiology
  • Cystic Fibrosis Research Advances
  • Organ and Tissue Transplantation Research
  • Abdominal vascular conditions and treatments
  • Maternal and Neonatal Healthcare
  • Intestinal Malrotation and Obstruction Disorders

Hospital Israelita Albert Einstein
2013-2024

Universidade de São Paulo
2008-2011

Universidade Federal de Juiz de Fora
2004-2010

Goals To compare the safety and length of hospitalization (LOH) between a full solid diet as initial meal for refeeding after mild acute pancreatitis (AP) compared with 2 other diets. Background In AP, need fat restriction during has not been studied. It was hypothesized that reintroduction oral feeding AP safe might result in shorter LOH. Study Subjects were randomized to receive 1 3 diets (clear liquid, soft, or solid) refeeding. Diet progression hospital discharge decided by physicians...

10.1097/mcg.0b013e3181c986b3 article EN Journal of Clinical Gastroenterology 2010-03-26

Prospective study of 200 patients with hepatocellular carcinoma (HCC) that underwent liver transplant (LT) after drug-eluting beads transarterial chemoembolization (DEB-TACE) for downstaging versus bridging. Overall survival and tumor recurrence rates were calculated, eligibility LT, time on the waiting list radiological response compared. After TACE, only within Milan Criteria (MC) transplanted. More LT in bridging group. Five-year post-transplant overall survival, recurrence-free has no...

10.3748/wjg.v25.i37.5687 article EN cc-by-nc World Journal of Gastroenterology 2019-09-28

Liver transplantation (LT) is the treatment of choice for patients with unresectable early hepatocellular carcinoma (HCC). Post-LT HCC recurrence rates range from 8 to 20% and still impact on overall survival (OS). The aim our study was evaluate post-LT analyze prognostic factors among those recurrence.

10.1097/meg.0000000000001448 article EN European Journal of Gastroenterology & Hepatology 2019-06-07

We reviewed the current status of liver transplantation in Latin America. used data from American and Caribbean Transplant Society national organizations societies, as well information obtained local transplant leaders. America has a population 589 million (8.5% world population) more than 2,500 transplantations are performed yearly (17% activity), resulting 4.4 transplants per people (pmp) year. The number grows at 6% year region, particularly Brazil. top rates were found Argentina (10.4...

10.1097/tp.0000000000000198 article EN Transplantation 2014-07-11

Hepatocellular carcinoma (HCC) is one of the leading causes cancer-related mortality worldwide. The Brazilian Society Hepatology (SBH) published in 2015 its first recommendations about management HCC. Since then, new data have emerged literature, prompting governing board SBH to sponsor a single-topic meeting August 2018 São Paulo. All invited experts were asked make systematic review literature reviewing HCC subjects with cirrhosis. After meeting, all panelists gathered together for...

10.1590/s0004-2803.202000000-20 article EN cc-by-nc Arquivos de Gastroenterologia 2020-01-01

In acute pancreatitis (AP), oral refeeding may stimulate pancreatic secretion, increasing the inflammation of glandular tissue causing relapse abdominal pain or even exacerbation disease. This study aimed to assess prevalence and risk factors over in patients convalescing with AP as well impact recurrence on hospital stay.Inclusion criteria were confirmed by biochemical and/or radiological data absence severe disease extensive necrosis. The same diet was offered all during refeeding....

10.1111/j.1440-1746.2005.03986.x article EN Journal of Gastroenterology and Hepatology 2005-08-10

A substantial number of patients with Crohn's disease (CD) become dependent on steroids after induction therapy. Treatment azathioprine (AZA) may be beneficial in such patients. The present open-label study evaluated the long-term safety and efficacy AZA steroid-dependent CD patients.Adult were enrolled for therapy over a 7-year period. average dose was 2.0-3.0 mg/kg per day, adjusted according to clinical response occurrence adverse effects. Steroid tapered off predefined schedule....

10.1111/j.1440-1746.2006.04393.x article EN Journal of Gastroenterology and Hepatology 2006-06-13

The time that patients with hepatocellular carcinoma (HCC) can safely remain on the waiting list for liver transplantation (LT) is unknown. We investigated whether impacts transplant survival of HCC candidates and recipients. This a single-center retrospective study 283 adults HCC. Patients were divided in groups according to waiting-list time. main endpoint was survival. median LT 4.9 months. dropout rates at 3-, 6-, 12-months 6.4%, 12.4%, 17.7%, respectively. Mortality 4.8%, but varied...

10.1111/ajt.13011 article EN cc-by-nc-nd American Journal of Transplantation 2015-02-03

OBJETIVO: Propor um sistema de graduação para a disfunção precoce do enxerto hepático. MÉTODOS: Estudo retrospectivo único centro transplantador. Foram incluídos receptores transplante hepático por doador falecido transplantados pelo MELD. A foi definida segundo os critérios Olthoff. Diversos pontos corte testes laboratório pós-transplante foram utilizados criar da enxerto. O principal desfecho perda aos 6 meses. RESULTADOS: pico aminotransferases durante primeira semana pós-operatória se...

10.1590/s1679-45082013000100006 article PT cc-by Einstein (São Paulo) 2013-03-01

To establish the efficacy and safety of a 7-d therapeutic regimen using omeprazole, bismuth subcitrate, furazolidone amoxicillin in patients with peptic ulcer disease who had been previously treated other regimens without success.Open cohort study which included unsuccessfully one or more eradication regimens. The consisted 20 mg 240 colloidal 1000 amoxicillin, 200 furazolidone, taken twice day for 7 d. Patients were considered as eradicated when samples from gastric antrum corpus 12 wk...

10.3748/wjg.14.6224 article EN cc-by-nc World Journal of Gastroenterology 2008-01-01

Introduction: The scheme proton pump inhibitor/amoxicillin/clarithromycin (PPI/AC) is still the first-line treatment for Helicobacter pylori (H. pylori) infections despite evidence suggesting its failure in up to 20% 30% of patients. Methodology: This study involved 493 patients who were prescribed omeprazole (20 mg twice a day) or another inhibitor equivalent dosage, amoxicillin (1 g day), and clarithromycin (500 seven days. Efficacy was determined by negative urease test absence H. on...

10.3855/jidc.911 article EN cc-by The Journal of Infection in Developing Countries 2010-07-21

ABSTRACT Background and Aim Primary sclerosing cholangitis (PSC) has been shown to recur after liver transplantation (LT). Some studies have identified certain clinical laboratory variables associated with an increased risk for recurrent PSC (rPSC) in Caucasians. Furthermore, de novo cholangiocarcinoma (CCA) reported anecdotally patients rPSC. This study aims assess the prevalence of rPSC, identify its factors, investigate occurrence CCA a highly admixed population from Brazil. Methods All...

10.1111/ctr.70002 article EN Clinical Transplantation 2024-10-01

Hepatocellular carcinoma (HCC) is one of the main indications for orthotopic liver transplantation (OLT). In Brazil, selection criteria HCC an expanded version Milan Criteria (MC), so-called "Brazilian Criteria" (BMC). Our aims were to evaluate post-OLT outcomes in patients with and analyze BMC performance.We conducted a multicenter, retrospective cohort study, analyzing medical records 1,059 transplant recipients HCC. Tumor was staged according MC correlated overall survival (OS)...

10.1016/j.aohep.2020.100294 article EN cc-by-nc-nd Annals of Hepatology 2020-12-02
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