Peter Bossuyt
A5021791508- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Immunodeficiency and Autoimmune Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Autoimmune and Inflammatory Disorders
- Biosimilars and Bioanalytical Methods
- Colorectal Cancer Screening and Detection
- Autoimmune and Inflammatory Disorders Research
- Helicobacter pylori-related gastroenterology studies
- Celiac Disease Research and Management
- Meta-analysis and systematic reviews
- Gastrointestinal disorders and treatments
- Chronic Lymphocytic Leukemia Research
- Diverticular Disease and Complications
- Gastric Cancer Management and Outcomes
- Pharmaceutical studies and practices
- Diagnosis and treatment of tuberculosis
- Clostridium difficile and Clostridium perfringens research
- Clinical practice guidelines implementation
- Pregnancy and Medication Impact
- Systemic Lupus Erythematosus Research
- Gastrointestinal Tumor Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Ovarian function and disorders
Imelda Hospital
2016-2025
Inserm
2024
University of Calgary
2024
McGill University Health Centre
2024
University of Amsterdam
2007-2024
Public Health Service of Amsterdam
2006-2024
Amsterdam UMC Location Vrije Universiteit Amsterdam
2024
Amsterdam University Medical Centers
2022-2024
Universitair Ziekenhuis Leuven
2009-2023
KU Leuven
2007-2023
The literature contains a large number of potential biases in the evaluation diagnostic tests. Strict application appropriate methodological criteria would invalidate clinical most study results.To empirically determine quantitative effect design shortcomings on estimates accuracy.Observational features 184 original studies evaluating 218 Meta-analyses tests were identified through systematic search using MEDLINE, EMBASE, and DARE databases Cochrane Library (1996-1997). Associations between...
This article is the second in a series of two publications relating to European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on management disease. The first covers medical management; present addresses surgical management, including preoperative aspects drug before surgery. It also provides technical advice for variety common clinical situations. Both articles together represent recommendations ECCO disease an update previous guidelines.
Endoscopy plays an essential role in the diagnosis, management, prognosis, and surveillance of inflammatory bowel disease (IBD), but surprisingly there are few available guidelines.1,2 This prompted ECCO Guidelines Committee (GuiCom) members to promote a Consensus on appropriate indication application different endoscopic modalities IBD. Since development guidelines is expensive time-consuming process, this may help avoid duplication effort future. It also identify issues where evidence...
Background and Purpose The Rankin Scale is a frequently used handicap index in stroke outcome research. However, relatively little known about its validity. purpose of this study was to investigate the clinical meaning grades by identifying functional health aspects that contribute scores. Methods We studied 438 patients 6 months after stroke. Data were collected on following indicators: alertness, communication, independence, disability activities daily living, mobility, instrumental...
Background & AimsMost patients with Crohn's disease (CD) eventually require an intestinal resection. However, CD frequently recurs after We performed a randomized trial to compare the ability of infliximab vs placebo prevent recurrence.MethodsWe evaluated efficacy in preventing postoperative recurrence 297 at 104 sites worldwide from November 2010 through May 2012. All study had undergone ileocolonic resection within 45 days before randomization. Patients were randomly assigned (1:1) groups...
The efficacy and safety of risankizumab as compared with ustekinumab in patients Crohn's disease are unknown.
Importance The clinical effects of risankizumab (a monoclonal antibody that selectively targets the p19 subunit IL-23) for treatment ulcerative colitis are unknown. Objective To evaluate efficacy and safety when administered as an induction a maintenance therapy patients with colitis. Design, Setting, Participants Two phase 3 randomized trials were conducted. trial was conducted at 261 centers (in 41 countries) enrolled 977 from November 5, 2020, to August 4, 2022 (final follow-up on May 16,...
Abstract Background The primary objective of the VIVID-1 trial (NCT03926130) was to demonstrate efficacy and safety mirikizumab (miri), a p19-directed anti-IL-23 antibody, compared placebo (PBO) in patients (pts) with moderate-to-severe Crohn’s disease. Miri demonstrated statistically significant improvements co-primary all key secondary endpoints versus (vs) PBO1. Here we present results on comparisons miri ustekinumab (uste), p40 directed anti-IL-12/IL-23 inhibitor from Phase 3,...
We studied the merits of physical examination after inversion injury ankle in 160 consecutive patients. They had an explanatory operation if they a positive arthrogram and/or signs on delayed examination.
Objective. Our aim was to improve the accuracy and completeness of reporting studies diagnostic in order allow readers assess potential for bias a study evaluate generalizability its results.