A5089608392- Inflammatory Bowel Disease
- Microscopic Colitis
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Clostridium difficile and Clostridium perfringens research
- Celiac Disease Research and Management
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Mycobacterium research and diagnosis
- Systemic Lupus Erythematosus Research
- Eosinophilic Esophagitis
- Tuberculosis Research and Epidemiology
- Liver Diseases and Immunity
- Diverticular Disease and Complications
- Drug-Induced Hepatotoxicity and Protection
- Galectins and Cancer Biology
- Gastrointestinal motility and disorders
- Digestive system and related health
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Diagnosis and treatment of tuberculosis
- Pregnancy and Medication Impact
- Pharmacological Effects of Natural Compounds
Dayanand Medical College & Hospital
2016-2025
California State University, Fresno
2023
All India Institute of Medical Sciences
2022
Public Works Department Buildings and Roads
2014
University Gastroenterology
2013
Medical University of Vienna
2013
University Hospital of Hartlepool
1991
INTRODUCTION: Intravenous corticosteroids are the mainstay of treatment patients hospitalized with acute severe ulcerative colitis (ASUC). However, 30%–40% refractory to corticosteroids. We investigated whether addition tofacitinib improved responsiveness in ASUC. METHODS: This single-center, double-blind, placebo-controlled trial randomized adult ASUC (defined by Truelove Witts severity criteria) receive either (10 mg thrice daily) or a matching placebo for 7 days while continuing...
Celiac disease, as of today, is said to exist in almost all parts the world, although it rare among people purely African-Caribbean, Japanese and Chinese background. The disease has also been considered uncommon India until recently. Hospital records have revealed an increasing trend predominantly wheat-eating areas North India. aim present study was determine prevalence celiac school children Punjab, India.The carried out Ludhiana district Northern A total 4347 aged 3-17 years attending...
Abstract Objectives To study the role of faecal microbiota transplantation [FMT] in maintenance remission ulcerative colitis [UC]. Methods In this pilot study, patients with UC clinical achieved after multi-session FMT were randomly allocated to either or placebo colonoscopic infusion every 8 weeks, for 48 weeks. The standard care [SOC] therapy was continued all patients. primary endpoint steroid-free [Mayo score ≤2, subscores ≤1] at Week 48. Secondary endpoints achievement endoscopic...
Abstract Background The prevalence of ulcerative colitis (UC) is increasing in elderly populations, yet real-world data on the efficacy and safety tofacitinib this demographic remains limited. This study aimed to evaluate effectiveness patients (≥60 years) with moderate-to-severe UC treated at a tertiary care center North India. Methods cohort was conducted Dayanand Medical College Hospital, Ludhiana, from July 2022 June 2024. Elderly (aged ≥60 refractory conventional therapies were...
The therapeutic goal for treating ulcerative colitis (UC) patients has shifted to achieving mucosal healing over the past few years. However, at present, limited data is available on correlation between endoscopic findings and histological remission in with healing.This was a prospective observational study conducted period of 18 months (January 2014 June 2015) Dayanand Medical College Hospital, Ludhiana, Punjab, India. Patients diagnosed UC who had been clinical (n=76) least 6 were...
OBJECTIVES: Acute insults from viruses, infections, or alcohol are established causes of decompensation leading to acute-on-chronic liver failure (ACLF). Information regarding drugs as triggers ACLF is lacking. We examined data producing and analyzed clinical features, laboratory characteristics, outcome, predictors mortality in patients with drug-induced ACLF. METHODS: identified precipitants among prospective cohort the Asian Pacific Association Study Liver (APASL) Research Consortium...
Abstract Background Oral corticosteroids are first-line agents to induce remission in moderately active ulcerative colitis [UC], but associated with adverse effects. We compared the efficacy and safety of tofacitinib prednisolone for induction UC. Methods This was a single-centre, prospective, open-label, randomized, active-controlled pilot study. Eligible patients [aged ≥18 years] had Participants were randomly assigned receive either [40 mg daily, tapered by 5 every week] or [10 twice...
Hepatitis C virus (HCV) genotypes help to tailor the treatment response, but their influence on disease severity and association with hepatic steatosis is not well understood. The prevalence of HCV correlation histopathological liver in Indian patients were studied. HCV-RNA genotyping was carried out 398 chronic hepatitis C. Liver biopsy available 292 (73.4%) patients. graded basis histological activity index stage fibrosis. categorized as having mild (histological ≤5 and/or fibrosis ≤2) or...
<h3>Objective</h3> Over 100 ulcerative colitis (UC) loci have been identified by genome-wide association studies (GWASs) primarily in Caucasians (CEUs). Many of them weak effects on disease susceptibility, and the bulk heritability cannot be ascribed to these loci. Very little is known about genetic background UC non-CEU groups. Here we report first GWAS a genetically distinct north Indian (NI) population. <h3>Design</h3> A scan was performed 700 cases 761 controls. 18 single-nucleotide...
Genotype imputation of the human leukocyte antigen (HLA) region is a cost-effective means to infer classical HLA alleles from inexpensive and dense SNP array data. In research setting, helps avoid costs for wet lab-based typing thus renders association analyses in large cohorts feasible. Yet, most reference panels target Caucasian ethnicities multi-ethnic are scarce. We compiled high-quality panel based on genotypes measured with Illumina's Immunochip genotyping types established using...
See Editorial "Multi-session fecal microbiota transplantation using colonoscopy has favorable outcomes for the treatment of steroid-dependent ulcerative colitis" in Volume 17 on page 6.
Abstract Introduction These Asian Working Group guidelines on diet in inflammatory bowel disease (IBD) present a multidisciplinary focus clinical nutrition IBD countries. Methodology The are based evidence from existing published literature; however, if objective data were lacking or inconclusive, expert opinion was considered. conclusions and 38 recommendations have been subject to full peer review Delphi process which uniformly positive responses (agree strongly agree) required. Results...